Amtolmetin guacil manufacturers and suppliers

Amtolmetin guacil suppliers

Properties

Melting point:: 117-120°

Boiling point:: 663.3±55.0 °C(Predicted)

Density: 1.19±0.1 g/cm3(Predicted)

storage temp.: Sealed in dry,Room Temperature

solubility: DMSO (Slightly), Methanol (Slightly)

form: Solid

pka: 13.90±0.46(Predicted)

color: Pale Brown to Light Brown

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H302

Precautionary statements: P264-P270-P301+P312-P330-P501

Toxicity: LD50 in male mice, rats (mg/kg): 1370, 1100 i.p.; >1500, 1450 orally (Baglioni)

Use

Amtolmetin guacil is an orally active non-steroidal antiinflammatory drug (NSAID) introduced for the treatment of osteoarthritis, rheumatoid arthritis and post-operative pain. Amtolmetin guacil is reported to elicit a more rapid and improved analgesic action than other agents such as paracetamol. In models of adjuvant arthritis and rheumatic diseases, amtolmetin guacil is more efficacious than existing drugs such as naproxen, indomethacin and piroxicam. As a non-acidic prodrug of tolmetin, it has similar in vivo activity to the parent but with minor ulcerogenic action, lower acute toxicity, and excellent biological and gastric tolerability.

You can find Amtolmetin guacil suppliers, manufacturers, and distributors from countries such as CHINA, United States and the India here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.