Chlorzoxazone suppliers
Chlorzoxazone
- CAS:
- 95-25-0
- MF:
- C7H4ClNO2
- MW:
- 169.57
Suppliers by country/region
Company Type
Properties
- Melting point:
- 191-192 °C (lit.)
- Density
- 1.3771 (rough estimate)
- refractive index
- 1.5557 (estimate)
- storage temp.
- room temp
- solubility
- DMSO: soluble50mg/mL, clear
- pka
- pKa 8.3 (Uncertain)
- form
- Powder
- color
- white to off-white
- Water Solubility
- 0.1 g/100 mL
- Merck
- 14,2194
- LogP
- 1.816 (est)
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P264-P270-P301+P312-P302+P352-P305+P351+P338
- Hazard Codes
- Xn,T,Xi
- Risk Statements
- 22-36/37/38-20/21/22
- Safety Statements
- 26-36-24/25-37/39
- WGK Germany
- 3
- RTECS
- DM5250000
- Hazard Note
- Toxic/Irritant
- TSCA
- Yes
- HazardClass
- IRRITANT
- HS Code
- 29349990
- Toxicity
- LD50 in mice (mg/kg): 3650 orally, 380 i.p. (suspensions); 440 orally, 183 i.p. (solns of Na salt) (Hofrichter)
Use
Chlorzoxazone is a benzoxazolone derivative that causes skeletal muscle relaxation and blocks spasticity in clinical studies. Chlorzoxazone enhances small and intermediate conductance calcium-activated potassium channels (EC50s = 87 and 98 μM for KCa2.2 and KCa3.1, respectively). The cytochrome P450 isoform CYP2E1 converts chlorzoxazone to 6-hydroxy chlorzoxazone . The urinary excretion of this 6-hydroxy metabolite is often used as a probe of CYP2E1 activity in studies of hepatotoxicity.
281 supplier list of "Chlorzoxazone"
- Product Name:Chlorzoxazone API
- Products Intro:Purity: 99% | Package: 25KG;5KG;1KG
- Company Type: Trader
- Country/Region: CHINA
$1.00-2.00 / 1kg
- Product Name:Chlorzoxazone
- Products Intro:Purity: 99% | Package: 1kg;1USD|2kg;2USD
- Company Type: Reagent
- Country/Region: CHINA
- Main Products: Nicotinamide riboside chloride,Curcumin,L(+)-Ascorbic acid,L-Glutamine,Stevioside Basic information
- Product Name:Chlorzoxazone
- Products Intro:Purity: 0.99 | Package: 5KG;1KG
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Daily Chemicals
- Product Name:Chlorzoxazone
- Company Type: Service provider
- Country/Region: CHINA
- Main Products: UDDA
- Product Name:Chlorzoxazone
- Products Intro:Purity: 0.98 | Package: 1kg，2kg，5kg，10kg，25kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 2,7-ADA,2,4,6-Trichloroaniline,TRIMETHYLOXONIUM TETRAFLUOROBORATE,Zinc sulfide,5-HEXEN-1-OL
- Product Name:chlorzoxazone
- Products Intro:Purity: 99% | Package: 1kg
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Chlorzoxazone
- Company Type: Reagent
- Country/Region: CHINA
- Main Products: Gamma-butyrolactone
- Product Name:CHLORZOXAZONE
- Products Intro:Purity: 99% | Package: USP EP CP
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Pharmceutical,Optical Brightening,dyes
- Product Name:Chlorzoxazone
- Products Intro:Purity: 98.0% | Package: 1KG;0USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Linoleic Acid,Vitamin B12,Riboflavin,β-Nicotinamide Mononucleotide,Amoxicillin trihydrate
- Product Name:Chlorzoxazone
- Products Intro:Purity: 0.99 | Package: 25kg;1kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: API(Active Pharmaceutical Ingredient),Lab Fine Chemical,Phytochemistry,Cosmetic Raw Materials