Closantel manufacturers and suppliers

Closantel suppliers

Properties

Melting point:: 217.8°

Boiling point:: 590.5±50.0 °C(Predicted)

Density: 1.8759 (estimate)

storage temp.: Keep in dark place,Sealed in dry,2-8°C

solubility: DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2)(1:5): 0.16 mg/ml

pka: 5.99±0.48(Predicted)

Safety Information

Symbol(GHS): GHS06

Signal word: Danger

Hazard statements: H301-H413

Precautionary statements: P273-P301+P310+P330

Hazard Codes: Xn

Risk Statements: 22

RIDADR: 2811

WGK Germany: 3

RTECS: CV2444250

HazardClass: 6.1(b)

PackingGroup: III

Toxicity: A veterinary drug for the treatment of fluke and nematode infestations. In 1993, some was included in a batch of donated drugs sent to Lithuania. Attempts to match the product with the names of other medicines on accompanying literature resulted in its misidentification as a treatment for endometriosis. Eleven women lost their eyesight; though this has since returned, they were left with eye pain and are unable to work.

Use

Closantel is a kind of synthetic anti parasitic agent which is actively against liver fluke, bloodsucking nematodes and larval stages of some arthropods in sheep and cattle. Its mechanism of action is through decoupling the mitochondrial oxidative phosphorylation, thus inhibiting the production of ATP. Therefore, it inhibit their energy generation of the parasite, causing their death. It is mainly used for the treatment and prevention of several infections caused by many kinds of parasites such as Fasciola hepatica, Fasciola gigantica, Haemonchus concortus, Haemonchus placei, Bunostomum phlebotomum, Oesophagostomum radiatum and Strongyloides papillosus in cattle and sheep.

You can find Closantel suppliers, manufacturers, and distributors from countries such as China, United States and the India here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.