GS-441524 suppliers
GS-441524
- CAS:
- 1191237-69-0
- MF:
- C12H13N5O4
- MW:
- 291.26
Suppliers by country/region
Company Type
Properties
- Melting point:
- > 233° C (dec.)
- Density
- 1.84±0.1 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- Soluble in DMSO (>25 mg/ml)
- pka
- 12.13±0.70(Predicted)
- form
- solid
- color
- Off-white
- Stability:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
- InChI
- InChI=1/C12H13N5O4/c13-4-12(10(20)9(19)7(3-18)21-12)8-2-1-6-11(14)15-5-16-17(6)8/h1-2,5,7,9-10,18-20H,3H2,(H2,14,15,16)/t7-,9-,10-,12+/s3
- InChIKey
- BRDWIEOJOWJCLU-QHRJDZJMNA-N
- SMILES
- C([C@]1(C2=CC=C3C(=NC=NN23)N)[C@@H]([C@H](O)[C@@H](CO)O1)O)#N |&1:1,12,13,15,r|
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P280-P301+P312-P302+P352-P305+P351+P338
Use
GS-441524 is a nucleoside analogue antiviral drug which was developed by Gilead Sciences. It is the main plasma metabolite of the antiviral prodrug remdesivir, and has a half-life of around 24 hours in human patients. Remdesivir and GS-441524 were both found to be effective in vitro against feline coronavirus strains responsible for feline infectious peritonitis (FIP), a lethal systemic disease affecting domestic cats. Remdesivir was never tested in cats (though some vets now offer it[1]), but GS-441524 has been found to be effective treatment for FIP and is widely used despite no official FDA approval due to Gileads refusal to license this drug for veterinary use.
251 supplier list of "GS-441524"
![(2R,3R,4S,5R)-2-(4-AMINOPYRROLO[2,1-F][1,2,4]TRIAZIN-7-YL)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)TETRAHYDROFURAN-2-CARBONITRILE](https://img.chemicalbook.com/CompanyLogo/23f8fe59-01f4-4286-8c7d-45acdcbe314520200917165054.jpg)
- Product Name:(2R,3R,4S,5R)-2-(4-AMINOPYRROLO[2,1-F][1,2,4]TRIAZIN-7-YL)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)TETRAHYDROFURAN-2-CARBONITRILE
- Products Intro:Purity: 0.99 | Package: 5KG;1KG
- Company Type: Trader
- Country/Region: CHINA
- Product Name:1191237-69-0
- Products Intro:Purity: 99% | Package: 25KG;5KG;1KG
- Company Type: Trader
- Country/Region: CHINA
- Product Name:GS-441524
- Products Intro:Purity: 0.99 | Package: 1KG；2KG; 5KG；10KG;100KG | CustNote: Molecular Formula:C12H13N5O4 Molar Mass:291.26
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Trilostane,Pimobendan,Chloroambucil,Firocoxib,Demecarium bromide
$20.00-10.00 / 1kg
- Product Name:GS-441524
- Products Intro:Purity: 99%|Package: 1kg;20.00;USD|25kg;15.00;USD|500kg;10.00;USD
- Company Type: Manufacturer
- Country/Region: CHINA
- Main Products: lead acetate,Lead oxide,PMK ethyl glycidate,BMK Glycidic Acid,Diethyl(phenylacetyl)malonate
![(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)oxolane-2-carbonitrile](https://img.chemicalbook.com/CompanyLogo/b956baa4-896a-4761-a9a7-0ab42e68141b20200327092329.jpg)
- Product Name:(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)oxolane-2-carbonitrile
- Products Intro:Purity: 98%+|Package: 100g;0USD|500g|1KG|25KG
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Phytic acid,Ortho Nitrobenzaldehyde,Phthalide,4-Cyanophenol,P-tert-Butyl Benzoic Acid(PTBBA)