Ibuprofen manufacturers and suppliers

Ibuprofen suppliers

Properties

Melting point:: 77-78 °C

alpha: [α]D20 -1～+1°(c=1,C2H5OH)

Boiling point:: 157 °C (4 mmHg)

Density: 1.0364 (rough estimate)

refractive index: 1.5500 (estimate)

Flash point:: 9℃

storage temp.: 2-8°C

solubility: Practically insoluble in water, freely soluble in acetone, in methanol and in methylene chloride. It dissolves in dilute solutions of alkali hydroxides and carbonates.

pka: pKa 4.45± 0.04(H2O,t = 25±0.5,I=0.15(KCl))(Approximate)

form: Crystalline Powder

color: white to off-white

Water Solubility: insoluble

Merck: 14,4881

BCS Class: 2

Stability:: Stable. Combustible. Incompatible with strong oxidizing agents.

InChIKey: HEFNNWSXXWATRW-UHFFFAOYSA-N

LogP: 3.970

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H302-H319-H335

Precautionary statements: P261-P264-P270-P271-P301+P312-P305+P351+P338

Hazard Codes: Xn

Risk Statements: 22-63-51/53-39/23/24/25-23/24/25-11

Safety Statements: 36-61-36/37-45-16-7

HS Code: 29163920

Toxicity: LD50 in male mice, rats (mg/kg): 495, 626 i.p.; 1255, 1050 orally (Orzalesi)

Use

Ibuprofen (Advil, Motrin) is used as an analgesic and antipyretic as well as a treatment for rheumatoid arthritis and degenerative joint disease. The most frequently observed side effects are nausea, heartburn, epigastric pain, rash, and dizziness. Incidence of GI side effects is lower than with indomethacin.Visual changes and cross-sensitivity to aspirin have been reported. Ibuprofen inhibits COX-1 and COX-2 about equally. It decreases platelet aggregation, but the duration is shorter and the effect quantitatively lower than with aspirin. Ibuprofen prolongs bleeding times toward high normal value and should be used with caution in patients who have coagulation deficits or are receiving anticoagulant therapy.

You can find Ibuprofen suppliers, manufacturers, and distributors from countries such as CHINA, India and the United States here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.