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Salmeterol

CAS:
89365-50-4
MF:
C25H37NO4
MW:
415.57

Properties

Melting point:
75.5-76.5°
Boiling point:
603.0±55.0 °C(Predicted)
Density 
1.112±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
9.99±0.31(Predicted)

Safety Information

RTECS 
CZ6457000

Use

Antiasthmatic drugs are the drugs that can act on the different links of the asthma attack in order to relieve or prevent the attack of asthma. Salmeterol is a new long-acting beta 2 agonist antiasthmatic drug, derived from salbutamol, and closely linked to beta 2 receptor, resulting in more durable activation. Its chemical name is hydroxy naphthalate, which is white or white like powder with bitter taste. It was first developed by the British GlaxoSmithKline Co and was first listed in the UK in 1990. Its commodity name is Serevent, Salmeterol Xinafoate Aerosol,Sertindole and Salmeterol. It can inhibit the release of hypersensitivity mediators from the mast cells in the lung. It can inhibit the early and late phase reaction induced by inhalation antigen and reduce the hyperresponsiveness of the trachea. Clinical trials show that is salmeterol stronger than salbutamol. It has a longer duration effect to protect asthma caused by histamine induced bronchoconstriction and movement. It features long duration, small extrapulmonary effect and good tolerance. It is an ideal drug for the treatment of nocturnal attack and asthma. The pharmacokinetic study has indicated that this dose of this product twice a day, 50g each time. 5~15 min after 1 inhalation of 50 and 400g, the highest plasma concentration will be 0.1 to 0.2g /L and 1 ~ g/L respectively. This product is strongly metabolizing by hydrolysis, and most of the dosage is eliminated in 72h. The doses of 23% and 57% in 168h can be found in urine and feces respectively. In addition, salmeterol has a controlled effect on histamine, leukotrienes and prostaglandins. It is worth notice that this product can not be used with non selective beta blockers for the treatment of asthma, and it should be prudent for patients with asthma with heart disease. Salmeterol s common adverse reactions include hypokalemia, abnormal bronchospasm, tremor, headache, and palpitations. Its common beta agonists include: ephedrine, isoproterenol, salbutamol, terbutaline, clenbuterol, clorprenaline, tulobuterol, clenbuterol, procaterol, salmeterol, bambuterol, methoxyphenamine, rimiterol, bitolterol, sonarin, butero, fenoterol etc..

138 supplier list of "Salmeterol"

  • Product Name:Salmeterol
  • Products Intro:Purity: 0.99 | Package: 500g;1kg
  • Type of Enterprise: Trader
  • Country/Region: CHINA
  • TEL: 18518759099
  • Product Name:Salmeterol
  • Products Intro:Purity: 99.00% | Package: 100g,500g,1KG,10KG,100KG
  • Type of Enterprise: Reagent
  • Country/Region: CHINA
  • TEL: +86-371-66670886
  • Main Products: Speciality Chemicals
  • Product Name:Salmeterol
  • Products Intro:Purity: 99% | Package: 500G;1KG;5KG;25KG
  • Type of Enterprise: Trader
  • Country/Region: CHINA
  • TEL: 0371-55170693
  • Product Name:Salmeterol
  • Products Intro:Purity: As coa | Package: As request | CustNote: 89365-50-4
  • Type of Enterprise: Trader
  • Country/Region: CHINA
  • TEL: 008615858145714
  • Product Name:Salmeterol
  • Products Intro:Purity: 98.00% | Package: 1kg,10kg,50kg,100kg
  • Type of Enterprise: Trader
  • Country/Region: CHINA
  • TEL: 15950718863

    US $2.00/ 1kg

  • Product Name:Salmeterol
  • Products Intro:Purity: 99% | Package: 1kg;2USD
  • Type of Enterprise: Reagent
  • Country/Region: CHINA
  • TEL: +86-371-86658258
  • Main Products: Nicotinamide riboside chloride,Curcumin,L(+)-Ascorbic acid,L-Glutamine,Stevioside Basic information
  • Product Name:Salmeterol
  • Products Intro:Purity: 0.99 | Package: 1kg 25kg 200 kilograms per barrel
  • Type of Enterprise: Trader
  • Country/Region: CHINA
  • TEL: 18627774460
  • Product Name:Salmeterol
  • Products Intro:Purity: 0.98 | Package: 1kg,2kg,5kg,10kg,25kg
  • Type of Enterprise: Trader
  • Country/Region: CHINA
  • TEL: +86-13650506873

    US $0.01-1.00 / 1KG

  • Product Name:Salmeterol
  • Products Intro:Purity: 99% | Package: 1KG;0.01USD|25KG;0.1USD|200KG;1USD
  • Type of Enterprise: Trader
  • Country/Region: CHINA

    US $15.00-10.00 / 1KG

  • Product Name:Salmeterol
  • Products Intro:Purity: 99%+ HPLC|Package: 1KG;15USD|100KG;12USD|1000KG;10USD
  • Type of Enterprise: Trader
  • Country/Region: CHINA
  • TEL: +8613111626072 (WhatsApp)
  • Main Products: APIS,Pharmaceutical raw materials,Cosmetic raw materials,Industrial additives,Experimental reagent

Salmeterol Related Search:

4-Hydroxy-α1-[[[6-(3-phenylpropoxy)hexyl]aMino]Methyl]-1,3-benzenediMethanolSalmeterol Related Compound B (10 mg) (4-{1-Hydroxy-2-[6-(4-phenylbutan-2-yloxy)hexylamino]ethyl}-2-(hydroxymethyl)phenol)Salmeterol EP Impurity A1-Hydroxy-2-naphthoic acid4-Hydroxy-α1-[[[6-(2-phenylethoxy)hexyl]aMino]Methyl]-1,3-benzenediMethanolSalmeterol EP Impurity GSalMeterol EP IMpurity DSalMeterol Xinafoate Adduct IMpuritySalbutamol AcetonideSalMeterol EP IMpurity F3-AminophenolEthyl acrylateEthylparaben4-Aminophenol2-Aminophenol1,3-BenzenedimethanolTris(Hydroxymethyl)NitromethaneCHLOROPHOSPHONAZO III
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