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Saquinavir

CAS:
127779-20-8
MF:
C38H50N6O5
MW:
670.84

Properties

alpha 
D20 -55.9° (c = 0.5 in methanol)
Boiling point:
1015.0±65.0 °C(Predicted)
Density 
1.211±0.06 g/cm3(Predicted)
pka
11.05±0.46(Predicted)
Water Solubility 
35.8mg/L(25 ºC)

Safety Information

Use

Saquinavir mesylate, the first HIV protease inhibitor to reach the market, was launched in the U.S.A.. It is indicated for use in combination with approved nucleoside analogs for the treatment of advanced HIV infection. Saquinavir, a transition state analog of Phe-Pro, is a very potent and competitive inhibitor of HIV-1 and HIV-2 proteases with high specificity. Saquinavir inhibits the last stage in the replication process of HIV and prevents virion maturation in both acute and chronically infected cells. Combination of saquinavir with the nucleoside analogs such as zidovudine (AZT) or/and zalcitabine which inhibit the enzyme reverse transcriptase and target at an earlier stage in the HIV replication process, shows a greater than additive effect in increase in CD4 cell counts and reduction in viral load, with the combination delaying the onset of resistance to either drug alone. Saquinavir is well tolerated alone and in combination with A n .

107 supplier list of "Saquinavir"

  • Product Name:Saquinavir
  • Products Intro:Purity: >=98% | Package: 1g;USD
  • Type of Enterprise: Trader
  • Country/Region: UNITED STATES
  • TEL: 1-631-485-4226
  • Product Name:Saquinavir
  • Products Intro:Purity: 0.99 | Package: 25KG;5KG;1KG;500G
  • Type of Enterprise: Trader
  • Country/Region: CHINA
  • TEL: 0371-55170695
  • Product Name:saquinavir
  • Products Intro:Purity: 0.99 | Package: 1kg
  • Type of Enterprise: Trader
  • Country/Region: CHINA
  • TEL: 86-18523575427
  • Product Name:Saquinavir
  • Products Intro:Purity: 99% | Package: 1KG;USD
  • Type of Enterprise: Trader
  • Country/Region: CHINA
  • TEL: 0086-371-86658258

    US $0.01-1.00 / 1KG

  • Product Name:Saquinavir
  • Products Intro:Purity: 99% | Package: 1KG;0.01USD|25KG;0.1USD|200KG;1USD
  • Type of Enterprise: Trader
  • Country/Region: CHINA
  • Product Name:Saquinavir;Ro 31-8959
  • Products Intro:Purity: 100.00% | Package: 5 mg;10 mg;1 mL * 10 mM (in DMSO);2 mg | CustNote: REAGENT;FOR LABORATORY USE ONLY
  • Type of Enterprise: Trader
  • Country/Region: UNITED STATES
  • TEL: 781-999-5354
  • Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits
  • Product Name:saquinavir
  • Type of Enterprise: Reagent
  • Country/Region: CHINA
  • TEL: 0551-65418671
  • Main Products: Gamma-butyrolactone
  • Product Name:Saquinavir
  • Products Intro:Purity: 77799% | Package: 10kg 25kg 200 kilograms per barrel | CustNote: good
  • Type of Enterprise: Trader
  • Country/Region: CHINA
  • TEL: 86-571-88216897、88216896
  • Product Name:Saquinavir
  • Products Intro:Purity: 99% | Package: 100g
  • Type of Enterprise: Trader
  • Country/Region: CHINA
  • TEL: 18071025641
  • Main Products: Chlorogenic acid,Tea polyphenol,Acacetin,Gentiopicroside,Jatrorrhizine
  • Product Name:Saquinavir USP/EP/BP
  • Products Intro:Purity: 99.9% | Package: 25kgs/Drum;200kgs/Drum | CustNote: FDA GMP CEP Approved Manufacturer
  • Type of Enterprise: Trader
  • Country/Region: CHINA
  • TEL: 029-88380327, 17691182729

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