Sulbactam manufacturers and suppliers

Sulbactam suppliers

Properties

Melting point:: 154-157℃

alpha: D20 +251° (c = 0.01 in pH 5.0 buffer)

Boiling point:: 567.7±50.0 °C(Predicted)

Density: 1.62±0.1 g/cm3(Predicted)

storage temp.: 2-8°C

solubility: H2O: ≥18mg/mL

pka: 2.62±0.40(Predicted)

form: lyophilized powder

color: white to tan

optical activity: [α]/D ≥+225°, c = 1 in H2O

Water Solubility: Soluble in water at 18mg/ml

Merck: 14,8889

Stability:: Hygroscopic

InChI: 1S/C8H11NO5S/c1-8(2)6(7(11)12)9-4(10)3-5(9)15(8,13)14/h5-6H,3H2,1-2H3,(H,11,12)/t5-,6+/m1/s1

InChIKey: FKENQMMABCRJMK-RITPCOANSA-N

SMILES: CC1(C)[C@@H](N2[C@@H](CC2=O)S1(=O)=O)C(O)=O

CAS DataBase Reference: 68373-14-8

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H302

Precautionary statements: P301+P312+P330

Hazard Codes: Xn

Risk Statements: 22

Safety Statements: 24/25

WGK Germany: 3

HS Code: 29349990

Storage Class: 11 - Combustible Solids

Hazard Classifications: Resp. Sens. 1
Skin Sens. 1

REACH Registrations: Active

Use

Sulbactam is penicillanic acid sulfone or 1,1-dioxopenicillanicacid. This synthetic penicillin derivative is a potent inhibitorof S. aureus β-lactamase as well as many β-lactamaseselaborated by Gram-negative bacilli. Sulbactam has weak intrinsicantibacterial activity but potentiates the activity ofampicillin and carbenicillin against β-lactamase–producingS. aureus and members of the Enterobacteriaceae family. Itdoes not, however, synergize with either carbenicillin or ticarcillinagainst P. aeruginosa strains resistant to these agents.Failure of sulbactam to penetrate the cell envelope is a possibleexplanation for the lack of synergy.Fixed-dose combinations of ampicillin sodium and sulbactamsodium, marketed under the trade name Unasyn assterile powders for injection, have been approved for use inthe United States. These combinations are recommended forthe treatment of skin, tissue, intra-abdominal, and gynecologicalinfections caused by β-lactamase–producing strainsof S. aureus, E. coli, Klebsiella spp., P. mirabilis, B. fragilis,and Enterobacter and Acinetobacter spp.

You can find Sulbactam suppliers, manufacturers, and distributors from countries such as CHINA, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.