Budesonide manufacturers and suppliers

Budesonide suppliers

Properties

Melting point:: 221-232°C (dec.)

alpha: D25 +98.9° (c = 0.28 in methylene chloride)

Boiling point:: 464.79°C (rough estimate)

Density: 1.1046 (rough estimate)

refractive index: 1.4593 (estimate)

storage temp.: Store at RT

solubility: Practically insoluble in water, freely soluble in methylene chloride, sparingly soluble in ethanol (96 per cent).

form: powder

pka: 12.87±0.10(Predicted)

color: White to Off-White

Water Solubility: 21.53mg/L(temperature not stated)

Merck: 14,1468

BCS Class: 2

InChIKey: VOVIALXJUBGFJZ-KWVAZRHASA-N

Safety Information

Symbol(GHS): GHS08,GHS07

Signal word: Danger

Hazard statements: H361-H332-H317-H334-H312

Precautionary statements: P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P201-P202-P281-P308+P313-P405-P501-P261-P271-P304+P340-P312-P280-P302+P352-P312-P322-P363-P501-P261-P285-P304+P341-P342+P311-P501

Hazard Codes: Xn

Risk Statements: 40-36/37/38-20/21/22

Safety Statements: 22-36-26

WGK Germany: 3

RTECS: TU3723000

HS Code: 29372900

Toxicity: LD50 oral in rat: > 3200mg/kg

Use

Budesonide, 16α,17-[butylidenebis-(oxy)]-11β,21-dihydroxypregna-1,4-diene-3, 20-dione (Entocort), in oral capsules is used to treat Crohn disease. Theaffinity for the GC is approximately 200-fold greater than thatof hydrocortisone and 15-fold greater than that of prednisolone.Budesonide is a mixture of epimers, with the 22Rform having twice the affinity for the GR of the S epimer.This GC is metabolized by CYP3A4, and its levels can be increasedin the presence of potent CYP3A4 inhibitors.Budesonide is also used in an inhaled formulation for thetreatment of asthma.

You can find Budesonide suppliers, manufacturers, and distributors from countries such as CHINA, India and the United States here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.