CHROMOMYCIN A3 manufacturers and suppliers

CHROMOMYCIN A3 suppliers

Properties

Melting point:: 185℃

alpha: D23 -57° (ethanol)

Boiling point:: 780.13°C (rough estimate)

Density: 1.1451 (rough estimate)

refractive index: 1.6500 (estimate)

storage temp.: 2-8°C

solubility: Soluble in ethanol, DMSO, and ethyl acetate (10 mg/ml).

form: Yellow solid

pka: 4.54±0.60(Predicted)

color: Yellow

Merck: 13,2258

Stability:: Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

Safety Information

Symbol(GHS): GHS06

Signal word: Danger

Hazard statements: H300

Precautionary statements: P264-P270-P301+P310-P405-P501

Hazard Codes: T+,T

Risk Statements: 61-28

Safety Statements: 53-28-36/37/39-45

RIDADR: UN 3462 6.1/PG 1

WGK Germany: 3

RTECS: GB7875000

F: 3-8-10

HazardClass: 6.1(a)

PackingGroup: I

HS Code: 29419090

Toxicity: Excitation max: ~445 nm. Emission max: ~575 nm. Sol in ethanol, ethyl acetate, DMSO, methanol. LD50 in mice (mg/kg): 1.85 i.v. (Slavik, Carter).

Use

Chromomycin A3 is the major component of the chromomycin complex of the aureolic acid class, isolated from several Streptomyces species, and first reported in 1960. Chromomycin A3 exhibits a broad biological profile as an antibacterial, antifungal and antitumor agent. It binds reversibly to GC-specific DNA ligand in the minor groove which inhibits transcription, DNA gyrase and topoisomerase II activity. The intense UV spectrum and strong fluorescence makes chromomycin a useful stain for DNA.

You can find CHROMOMYCIN A3 suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.