Ethambutol manufacturers and suppliers

Ethambutol suppliers

Properties

Melting point:: 199-204℃

Boiling point:: 345℃

alpha: D25 +13.7° (c = 2 in water)

Density: 1.0048 (rough estimate)

refractive index: 1.4610 (estimate)

RTECS: EL3640000

Flash point:: >110°(230°F)

storage temp.: Keep in dark place,Sealed in dry,2-8°C

solubility: Soluble in DMSO

form: Powder

pka: pKa 6.6 (H2O) (Uncertain);9.5(H3O) (Uncertain)

color: White to off-white

Water Solubility: Soluble in water. Also soluble in chloroform and methylene chloride

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H302

Precautionary statements: P264-P270-P301+P312a-P330-P501a

Toxicity: LD50 oral in rat: 998mg/kg

Use

Ethambutol is active against several species of mycobacteria and nocardiae. MICs on solid media are: M. tuberculosis 0.5–2 mg/L; M. kansasii 1–4 mg/L; other slowly growing mycobacteria 2–8 mg/L; rapidly growing pathogens 2–16 mg/L; Nocardia spp. 8–32 mg/L. Resistance is uncommon and is a multistep process due to mutations in the embA, embB and embC gene cluster. A mutation in codon 306 of the embB gene predisposes to the development of resistance to a range of antituberculosis agents, possibly by affecting cell-wall permeability.

You can find Ethambutol suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.