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ChemicalBook >> CAS DataBase List >>Etomidate

Etomidate suppliers

Etomidate

CAS:
33125-97-2
MF:
C14H16N2O2
MW:
244.29

Company Type

Properties

Melting point:
72-74°C
alpha 
D20 +66° (c = 1 in ethanol)
Boiling point:
160-162 °C(Press: 1 Torr)
Density 
1.11±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: >10 mg/mL
form 
powder
pka
pKa 4.24(H2O t=25.0) (Uncertain)
color 
white
Merck 
14,3881

Safety Information

Symbol(GHS) 
GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS09
Signal word 
Warning
Hazard statements 
H302-H400
Precautionary statements 
P301+P312+P330
Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
36
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3
RTECS 
NI4021500
HazardClass 
9
PackingGroup 
III
HS Code 
29332900
Toxicity
LD50 in mice, rats (mg/kg): 29.5, 14.8-24.3 i.v. (Janssen)

Use

Etomidate is an ultra-short effect non-barbiturate intravenous anesthetic agent allowed to be used in China , it belongs to imidazole derivatives. Hypnotic effect of Etomidate is strong , and its efficacy is about 12 times higher than thiopental, it has no analgesic effect. It has a rapid onset of anesthesia, after 20 seconds of intravenous injection, it produces anesthesia, anesthesia is maintained for about 5 minutes, it is quick to wake up , increasing the dose will increase the duration of action accordingly.

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