Isoquinoline manufacturers and suppliers

Isoquinoline suppliers

Properties

Melting point:: 26-28 °C (lit.)

Boiling point:: 242-243 °C (lit.)

Density: 1.099 g/mL at 25 °C (lit.)

vapor pressure: 5Pa at 20℃

FEMA: 2978 | ISOQUINOLINE

refractive index: n20/D 1.623(lit.)

Flash point:: 225 °F

storage temp.: 2-8°C

solubility: 5g/l

form: Low Melting Solid

pka: 5.42(at 20℃)

color: Light brown

PH: 7.5 (5g/l, H2O, 20℃)

Odor: at 0.10 % in triacetin. sweet balsam herbal benzaldehyde anise

Odor Type: balsamic

Water Solubility: practically insoluble

Merck: 14,5222

JECFA Number: 1303

BRN: 107549

Dielectric constant: 10.7（20℃）

InChIKey: AWJUIBRHMBBTKR-UHFFFAOYSA-N

LogP: 2.08

Dissociation constant: 5.19 at 25℃

Safety Information

Symbol(GHS): GHS06

Signal word: Danger

Hazard statements: H302-H311-H315-H319-H412

Precautionary statements: P264-P273-P280-P301+P312-P302+P352+P312-P305+P351+P338

Hazard Codes: T

Risk Statements: 22-24-38-52/53-36/38-21/22-45

Safety Statements: 36/37-45-36/37/39-61-53

RIDADR: UN 2811 6.1/PG 3

WGK Germany: 2

RTECS: NW6825000

TSCA: Yes

HazardClass: 6.1

PackingGroup: II

HS Code: 29334900

Toxicity: LD50 orally in rats: 360 mg/kg (Smyth)

Use

Crude quinoline containing 83% quinoline, 15% isoquinoline and 2% methyl quinoline can be used as the raw material for the production of isoquinoline. However, the Distillation section from 237.5-239.5℃ and 243-246℃ is generally collected and used as the raw material for the extraction of isoquinoline. 13-28% of 2-methyl quinoline and 3.9% quinoline can be separated from this distillation section in the form of hydrochloride salt. The isoquinoline fraction reacted with 98% sulfuric acid at 35℃ in alcohol solution to produce isoquinoline sulfonate. Isoquinoline sulfonate crystallizes faster than its homologues in the cooling process. After filtration, recrystallization was carried out with 85% ethanol, and then decomposed with 20% ammonia water. The generated oil layer was firstly washed with water, and then rectified to collect the fraction at242-243℃to obtain Isoquinoline with purity greater than 95% It is separated by repeated freezing the coal tar with the boiling rangeat 238～250℃.

You can find Isoquinoline suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.