L-Tryptophan manufacturers and suppliers

L-Tryptophan suppliers

Properties

Melting point:: 289-290 °C (dec.)(lit.)

Boiling point:: 342.72°C (rough estimate)

alpha: -31.1 º (c=1, H20)

Density: 1.34

refractive index: -32 ° (C=1, H2O)

storage temp.: 2-8°C

solubility: 20% NH₃: 0.1 g/mL at 20 °C, clear, colorless

form: powder

pka: 2.46(at 25℃)

color: White to yellow-white

PH: 5.5-7.0 (10g/l, H2O, 20℃)

Odor: wh. cryst. or cryst. odorless powd., sl. bitter taste

optical activity: [α]20/D 31.5±1°, c = 1% in H2O

Water Solubility: 11.4 g/L (25 ºC)

Merck: 14,9797

BRN: 86197

Stability:: Stable. Incompatible with strong acids, strong oxidizing agents.

InChIKey: QIVBCDIJIAJPQS-VIFPVBQESA-N

LogP: 0.704 (est)

Safety Information

Symbol(GHS): GHS05,GHS02

Signal word: Danger

Hazard statements: H314-H225-H290

Precautionary statements: P501-P240-P210-P233-P234-P243-P241-P242-P264-P280-P370+P378-P390-P303+P361+P353-P301+P330+P331-P363-P304+P340+P310-P305+P351+P338+P310-P403+P235-P406-P405

Hazard Codes: Xi

Risk Statements: 33-40-62-41-37/38-36/37/38-22

Safety Statements: 24/25-36/37/39-36-26

WGK Germany: 2

RTECS: YN6130000

F: 8

TSCA: Yes

HS Code: 29339990

Toxicity: LD508mmol / kg (rat, intraperitoneal injection). It is safe when used in food (FDA, §172.320, 2000).

Use

L-tryptophan, an essential aminoacid and precursor of serotonin, was introduced into medicine in 1963 for the treatment of depression and sleep disorders. Its effectiveness in these conditions has, however, never been convincingly demonstrated. It is also widely used in dietary supplements, parenteral nutrition preparations and dietary products for children with phenylketonuria. In 1989, reports from the USA showed an association between the consumption of L-tryptophan containing preparations and the development of eosiniphilia-myalgia syndrome (EMS), a condition characterized by intense eosinophilia, severe muscle and joint pain, swelling of the arms and legs, skin rashes and possible fever. Some of the reported cases have been fatal. Since it is not yet clear whether L-tryptophan itself or an unidentified contaminant is the cause of the EMS, many drug regulatory authorities have suspended the marketing authorization of products containing tryptophan pending further investigation, whereas others have withdrawn these products or restricted their use.

You can find L-Tryptophan suppliers, manufacturers, and distributors from countries such as CHINA, United States and the India here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.