MS023 manufacturers and suppliers

MS023 suppliers

MS023

CAS:: 1831110-54-3

MF:: C17H25N3O

MW:: 287.4

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Properties

Boiling point:: 437.8±45.0 °C(Predicted)

Density: 1.075±0.06 g/cm3(Predicted)

storage temp.: -20°C

solubility: ≥28.7 mg/mL in DMSO; ≥13.7 mg/mL in EtOH; ≥23.3 mg/mL in H2O

form: powder

pka: 17.44±0.50(Predicted)

color: white to light brown

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H302-H315-H319-H335

Precautionary statements: P261-P305+P351+P338

Use

MS023 is a potent, selective, and cell-active inhibitor of human type PRMTs (protein arginine methyltransferase), which is involved in many biological processes. Overexpression of PRMTs is related to some cancers. Therefore, MS023 is a useful chemical tools for testing biological and therapeutic hypotheses. MS023 displayed high potency for type I PRMTs including PRMT1, -3, -4, -6, and -8 but was completely inactive against type II and type III PRMTs, protein lysine methyltransferases and DNA methyltransferases. MS023 potently decreased cellular levels of histone arginine asymmetric dimethylation. It also reduced global levels of arginine asymmetric dimethylation and concurrently increased levels of arginine monomethylation and symmetric dimethylation in cells.

You can find MS023 suppliers, manufacturers, and distributors from countries such as CHINA, United States here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.