Nalidixic acid suppliers
Nalidixic acid
- CAS:
- 389-08-2
- MF:
- C12H12N2O3
- MW:
- 232.24
Suppliers by country/region
Company Type
Properties
- Melting point:
- 227-229 °C (lit.)
- Boiling point:
- 374.4°C (rough estimate)
- Density
- 1.2243 (rough estimate)
- refractive index
- 1.6660 (estimate)
- storage temp.
- 2-8°C
- solubility
- chloroform: 20 mg/mL, clear
- pka
- pKa 6.11± 0.02(Approximate)
- form
- Powder
- color
- White to light yellow
- Water Solubility
- 0.1 G/L (23 ºC)
- Merck
- 14,6359
- BRN
- 750515
- Stability:
- Stable. Incompatible with strong oxidizing agents.
Safety Information
- Symbol(GHS)
GHS07,GHS08
- Signal word
- Warning
- Hazard statements
- H302-H351
- Precautionary statements
- P202-P264-P270-P280-P301+P312-P308+P313
- Hazard Codes
- Xn
- Risk Statements
- 63-42/43-40-20/21/22-22
- Safety Statements
- 22-36/37-45-24-36
- WGK Germany
- 2
- RTECS
- QN2885000
- F
- 8-10-23
- HS Code
- 29339190
- Toxicity
- LD50 in mice (mg/kg): 3300 orally; 500 s.c.; 176 i.v. (Lesher, 1962)
Use
1-Ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid (NegGram) occurs as a pale buff crystalline powder that is sparingly soluble in water and ether but solublein most polar organic solvents.Nalidixic acid is useful in the treatment of urinary tractinfections in which Gram-negative bacteria predominate.The activity against indole-positive Proteus spp. is particularlynoteworthy, and nalidixic acid and its congeners representimportant alternatives for the treatment of urinary tractinfections caused by strains of these bacteria resistant toother agents. Nalidixic acid is rapidly absorbed, extensivelymetabolized, and rapidly excreted after oral administration.The 7-hydroxymethyl metabolite is significantly more activethan the parent compound. Further metabolism of theactive metabolite to inactive glucuronide and 7-carboxylicacid metabolites also occurs. Nalidixic acid possesses at1/2elim of 6 to 7 hours. It is eliminated, in part, unchanged inthe urine and 80% as metabolites.
332 supplier list of "Nalidixic acid"
$0.00/ 1kg
- Product Name:Nalidixic acid
- Products Intro:Purity: 0.99|Package: 1kg;0.00;USD
- Company Type: Manufacturer
- Country/Region: CHINA
- Main Products: lead acetate,Lead oxide,PMK ethyl glycidate,BMK Glycidic Acid,Diethyl(phenylacetyl)malonate
$2.00/ 1kg
- Product Name:Nalidixic acid
- Products Intro:Purity: 99% | Package: 1kg;2USD
- Company Type: Reagent
- Country/Region: CHINA
- Main Products: Nicotinamide riboside chloride,Curcumin,L(+)-Ascorbic acid,L-Glutamine,Stevioside Basic information
$0.01-1.00 / 1KG
- Product Name:Nalidixic Acid
- Products Intro:Purity: 99% | Package: 1KG;0.01USD|25KG;0.1USD|100KG;1USD
- Company Type: Trader
- Country/Region: CHINA