PALMITOYLETHANOLAMIDE manufacturers and suppliers

Palmitoylethanolamide suppliers

Properties

Melting point:: 97-98℃

Boiling point:: 461.5±28.0 °C(Predicted)

Density: 0.910±0.06 g/cm3(Predicted)

vapor pressure: 0.45Pa at 20℃

RTECS: ML8950000

storage temp.: -20°C

solubility: Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).

pka: 14.49±0.10(Predicted)

form: White solid

color: White

Water Solubility: 4.01mg/L at 20℃

Stability:: Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.

InChIKey: HXYVTAGFYLMHSO-UHFFFAOYSA-N

LogP: 3.989 at 20℃

Safety Information

Symbol(GHS): GHS05,GHS09

Signal word: Danger

Hazard statements: H315-H318-H411

Precautionary statements: P264-P273-P280-P302+P352-P305+P351+P338-P332+P313

WGK Germany: 2

TSCA: Yes

HS Code: 2934.99.4400

Use

Palmitoylethanolamide (PEA) is an endogenous fatty acid mediator that is synthetized from membrane phospholipids by N-acyl phosphatidylethanolamine phospholipase D. Its biological actions are primarily mediated by PPAR-α (peroxisome proliferator-activated receptors α) and the orphan receptor GPR55. Palmitoylethanolamide exerts potent anti-inflammatory actions but its physiological role and promise as a therapeutic agent in chronic arterial inflammation, such as atherosclerosis remain unexplored. It was initially described as an agonist to the type 2 cannabinoid receptor (CB2), though it is now recognized that PEA does not bind to cannabinoid receptors. PEA is known to have anti-inflammatory, analgesic, and neuroprotective properties. PEA supplements have been used by people with chronic pain as well as those with neuropathic pain.

You can find Palmitoylethanolamide suppliers, manufacturers, and distributors from countries such as China, United States and the India here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.