Pepstatin manufacturers and suppliers

Pepstatin suppliers

Properties

Melting point:: 233 °C (dec.)(lit.)

alpha: D27 -90.3° (c = 0.288 in methanol)

Boiling point:: 695.91°C (rough estimate)

Density: 1.1340 (rough estimate)

refractive index: 1.7500 (estimate)

storage temp.: 2-8°C

solubility: 10% acetic acid in methanol: 1 mg/mL

pka: 4.17±0.10(Predicted)

form: White solid

color: Colorless needles

optical activity: Optical rotation: -90.0 ± 5° (c = 0.5, MeOH, 20°C).

Water Solubility: It is soluble in 10% (v/v) acetic acid in methanol (9:1 methanol:acetic acid) (1 mg/ml), ethanol (1-2 mg/ml with heat up to 60°C), DMSO (5 mg/ml), methanol (1 mg/ml), and acetic acid. Insoluble in benzene, chloroform, water, 1 M NaOH, and ether.

BRN: 2201362

Stability:: Stable. Incompatible with strong bases, strong acids.

InChIKey: JKGWASGTXVCDML-LXTPJMTPSA-N

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H315-H319-H335

Precautionary statements: P261-P305+P351+P338

Safety Statements: 22-24/25

WGK Germany: 2

RTECS: SC6155000

F: 10

HS Code: 29241990

Toxicity: LD50 in mice, rats, rabbits, dogs (mg/kg): 1090, 875, 820, 450 i.p.; all >2000 orally (Umezawa, 1970)

Use

As an aspartic proteases irreversible inhibitor, Pepstain A can be used in conjunction with E64-d and Leupeptin A to inhibit the degradation of autophagic cargo inside autophagosomes.

You can find Pepstatin suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.