Phenylbutazone manufacturers and suppliers

Phenylbutazone suppliers

Properties

Melting point:: 106-108 °C (lit.)

Boiling point:: 448.76°C (rough estimate)

Density: 1.1591 (rough estimate)

refractive index: 1.6140 (estimate)

storage temp.: 2-8°C

solubility: Practically insoluble in water, sparingly soluble in alcohol. It dissolves in alkaline solutions.

form: Powder

pka: 4.5(at 25℃)

color: White to almost white

Water Solubility: <0.1 g/100 mL at 23.5 ºC

Merck: 14,7277

BRN: 290080

Stability:: Stable. Incompatible with strong oxidizing agents, strong acids, strong bases.

InChIKey: VYMDGNCVAMGZFE-UHFFFAOYSA-N

LogP: 3.160

Safety Information

Symbol(GHS): GHS06

Signal word: Danger

Hazard statements: H301-H312+H332-H315-H319-H335

Precautionary statements: P261-P280-P301+P310-P302+P352+P312-P304+P340+P312-P305+P351+P338

Hazard Codes: Xn,T,F

Risk Statements: 36/37/38-20/21/22-42/43-45-36-11

Safety Statements: 36/37/39-26-45-22-53-36/37-16

RIDADR: 3249

WGK Germany: 3

RTECS: UQ8225000

TSCA: Yes

HazardClass: 6.1(b)

PackingGroup: III

HS Code: 29331990

Toxicity: LD50 oral in rabbit: 781mg/kg

Use

Phenylbutazone, a pyrazolone derivative with anti-inflammatory, analgesic and antipyretic activity, was introduced in 1949 for the treatment of rheumatic disorders. Its use was subsequently associated with serious and sometimes fatal adverse reactions, notably cases of aplastic anaemia and agranulocytosis. Many national drug regulatory authorities consider that more recently introduced drugs offer a safer alternative for most, if not all, patients requiring anti-inflammatory agents. Phenylbutazone has thus been either withdrawn at the national level or retained with rigorously restricted indications for patients unresponsive to other therapy. These restrictions also apply, in general, to combination products containing phenylbutazone.

You can find Phenylbutazone suppliers, manufacturers, and distributors from countries such as China, United States and the India here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.