Quinine manufacturers and suppliers

Quinine suppliers

Properties

Melting point:: 173-175 °C(lit.)

alpha: -172 º (c=1, EtOH)

Boiling point:: 462.75°C (rough estimate)

Density: 1.1294 (rough estimate)

vapor pressure: 0Pa at 25℃

refractive index: 1.6250 (estimate)

Flash point:: >110°C (>230°F)

storage temp.: Keep in dark place,Inert atmosphere,Room temperature

solubility: H2O: soluble

form: Crystalline Powder

pka: 8.52(at 25℃)

color: White

PH Range: Blue I uorescence (3.0) to weak violet I uorescence (5.0);Weak violet I uorescence (9.5) to nonI uorescence (10.0)

PH: 9.0 (0.5g/l, H2O, 20℃)

optical activity: [α]25/D 165°, c = 2 in ethanol

Odor Type: odorless

Water Solubility: slightly soluble

Hydrolytic Sensitivity: 2: reacts with aqueous acid

Sensitive: Light Sensitive

Merck: 14,8061

BRN: 91867

Major Application: Bird repellents, sunscreen, antimalarial agent, antiviral agent, antitumor agent, drug-coated coronaryagent, antiparasitic agent, treatment of epilepsy, skeletal muscle spasm, drug-coated coronary stent system

LogP: 3.17 at 25℃

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H302-H317

Precautionary statements: P261-P264-P280-P301+P312+P330-P302+P352-P333+P313

Hazard Codes: Xn,Xi

Risk Statements: 36/37/38-42/43-22-20/22-20/21/22-36/38

Safety Statements: 22-26-36/37-45-37/39-36-7

RIDADR: 1544

WGK Germany: 3

RTECS: VA6020000

F: 8

HazardClass: 6.1(b)

PackingGroup: III

HS Code: 29392110

Toxicity: Antimalarial still used primarily for treatment of plasmodium resistant to synthetic antimalarials. Also used as antipyretic for colds, influenza, and cramp; quinine may have toxic effects on the eye, apparently due to an immune reaction, and may also affect male reproductive capacity.

Use

Quinines use as an antimalarial agent spans several hundred years, but it has been replaced in recent years by other substances such as chloroquine. Because some Plasmodium strains have developed resistance to several malaria medications, quinine use is being revived. About 60% of quinine production is used for medicinal purposes, and the drug is available by prescription. In addition to its use as an antimalarial agent, quinine medications are used to treat leg cramps, muscle cramps associated with kidney failure, hemorrhoids, heart palpitations, and as an analgesic. At higher concentrations it is toxic and causes a condition known as cinchonism. Conditions associated with cinchonism include dizziness, hearing loss, visual impairment, nausea, and vomiting.Nonmedicinal use of quinine, accounting for about 40% of its use, is primarily as a fl avoringagent in condiments and liqueurs. The most common food use of quinine is tonic water. Tonicwater originated in India where English colonists drank carbonated water mixed with quinineto prevent malaria. The bitter taste of quinine was often masked by mixing it with alcoholicbeverages; one result of this practice was the drink gin and tonic. Current Food and DrugAdministration regulations in the United States limit the amount of quinine in tonic water to83 parts per million (83 mg per liter). This level is signifi cantly less than that required for therapeuticpurposes, so the use of commercial tonic waters to combat malaria is not practical.

You can find Quinine suppliers, manufacturers, and distributors from countries such as CHINA, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.