Verapamil suppliers
Verapamil
- CAS:
- 52-53-9
- MF:
- C27H38N2O4
- MW:
- 454.61
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Properties
- Melting point:
- 25°C
- Boiling point:
- 243-246 °C (1.3 Pa)
- Density
- 1.1267 (rough estimate)
- refractive index
- 1.5448
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- DMSO: 100 mg/mL (219.97 mM)
- form
- Thick Oil
- pka
- 8.6(at 25℃)
- color
- Colourless
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P280-P301+P312-P302+P352-P305+P351+P338
- Toxicity
- LD50 oral in rat: 163mg/kg
Use
Verapamil, 5-[. Hemodynamically, verapamil causesa change in the preload, afterload, contractility, heart rate,and coronary blood flow. The drug reduces systemic vascularresistance and mean blood pressure, with minor effectson cardiac output.Verapamil is a synthetic compound possessing slightstructural similarity to papaverine. It can be separated intoits optically active isomers, of which the levorotatory enantiomeris the most potent. It is absorbed rapidly after oraladministration. The drug is metabolized quickly and, as aresult, has low bioavailability. The liver is the main siteof first-pass metabolism, forming several products. Thepreferential metabolic step involves N-dealkylation, followedby O-demethylation, and subsequent conjugation ofthe product before elimination. The metabolites have no significantbiological activity. Verapamil has an eliminationhalf-life of approximately 5 hours.
107 supplier list of "Verapamil"
$3.00/ 1KG
- Product Name:Verapamil
- Products Intro:Purity: 98% | Package: 1KG;3USD
- Company Type: Trader
- Country/Region: CHINA
- Product Name:verapamil
- Company Type: Reagent
- Country/Region: CHINA
- Main Products: Gamma-butyrolactone
- Product Name:Verapamil
- Products Intro:Purity: 99% | Package: 1KG;25kg;200kg;1000kg Sun | CustNote: g-kg-tons,free sample is available.Bottle/drum/IBC.Advantage products,new batches,regular stock, ready for shipment.
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Chemical raw materials,Organic raw materials,Petrochemicals,Chemical reagents,Intermediates