1,4-Dioxane

Melting point :12 °C
Boiling point :101 °C
Density :1.034 g/mL at 25 °C(lit.)
vapor density :3 (vs air)
vapor pressure :27 mm Hg ( 20 °C)
refractive index :n20/D 1.422(lit.)
Flash point :54 °F
storage temp. :room temp
solubility :Soluble in acetone, alcohol, benzene, and ether (Weast, 1986). Miscible with most organic solvents (Huntress and Mulliken, 1941) including 2-methylpropanol, toluene, cychexanone, and cyclopentanone.
form :Solution
color :APHA: ≤20
Odor :Mild ether-like odor detectable at 0.8 to 172 ppm (mean = 12 ppm)
PH :6-8 (500g/l, H2O, 20℃)
explosive limit :1.7-25.2%(V)
Water Solubility :SOLUBLE
Sensitive :Hygroscopic
λmax :λ: 220 nm Amax: ≤0.70
λ: 235 nm Amax: ≤0.50
λ: 250 nm Amax: ≤0.20
λ: 270 nm Amax: ≤0.10
λ: 295-400 nm Amax: ≤0.01 Merck :14,3300
BRN :102551
Henry's Law Constant :4.89(x 10^-6 atm?m³/mol) (static headspace-GC, Welke et al., 1998)
Exposure limits :TLV-TWA 25 ppm (≈90 mg/m³) (ACGIH), 100 ppm (MSHA and OSHA); carcinogenicity: Animal Sufficient Evidence (IARC).
Dielectric constant :2.2（25℃）
Stability :Stable. Incompatible with oxidizing agents, oxygen, halogens, reducing agents, moisture. Highly flammable - note wide explosive range. May form explosive peroxides in storage (rate of formation increased by heating, evaporation or exposure to light).
InChIKey :RYHBNJHYFVUHQT-UHFFFAOYSA-N
LogP :-0.42 at 20℃
CAS DataBase Reference :123-91-1(CAS DataBase Reference)
IARC :2B (Vol. 11, Sup 7, 71) 1999
NIST Chemistry Reference :1,4-Dioxane(123-91-1)
EPA Substance Registry System :1,4-Dioxane (123-91-1)

Symbol(GHS):
Signal word:	Danger
Hazard statements:	Code Hazard statements Hazard class Category Signal word Pictogram P-Codes H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501 H304 May be fatal if swallowed and enters airways Aspiration hazard Category 1 Danger H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362 H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning H340 May cause genetic defects Germ cell mutagenicity Category 1A, 1B Danger H350 May cause cancer Carcinogenicity Category 1A, 1B Danger H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger P260, P264, P270, P314, P501 H412 Harmful to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 3 P273, P501
Precautionary statements:	P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P273 Avoid release to the environment. P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P331 Do NOT induce vomiting.