1,1'-(9-(2-(isopropylamino)ethyl)-9H-carbazole-3,6-diyl)bis(ethan-1-one)
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- $47 - $1800
- Product name: 1,1'-(9-(2-(isopropylamino)ethyl)-9H-carbazole-3,6-diyl)bis(ethan-1-one)
- CAS: 1197996-80-7
- MF: C21H24N2O2
- MW: 336.43
- EINECS:
- MDL Number:MFCD18071578
- Synonyms:1,1'-(9-(2-(isopropylamino)ethyl)-9H-carbazole-3,6-diyl)bis(ethan-1-one);CBL0137; CBL-0137; CBL 0137; CURAXIN;CBLC 137;Curaxin 137;Ethanone, 1,1'-[9-[2-[(1-methylethyl)amino]ethyl]-9H-carbazole-3,6-diyl]bis-;CBL0137;Curaxin;1-[6-acetyl-9-[2-(propan-2-ylamino)ethyl]carbazol-3-yl]ethanone
7 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Cayman Chemical
- DC Chemicals
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number3372DF
- Product descriptionCBL-0137freebase
- Packaging25mg
- Price$455
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3171
- Product descriptionCBL0137
- Packaging1mg
- Price$123
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number19110
- Product descriptionCBL0137 ≥95%
- Packaging1mg
- Price$47
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19110
- Product descriptionCBL0137 ≥95%
- Packaging5mg
- Price$160
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19110
- Product descriptionCBL0137 ≥95%
- Packaging10mg
- Price$295
- Updated2024-03-01
- Buy
- ManufacturerDC Chemicals
- Product numberDC10617
- Product descriptionCBL0137 >98%
- Packaging250mg
- Price$900
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC10617
- Product descriptionCBL0137 >98%
- Packaging1g
- Price$1800
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 3372DF | CBL-0137freebase | 25mg | $455 | 2021-12-16 | Buy |
| ApexBio Technology | C3171 | CBL0137 | 1mg | $123 | 2021-12-16 | Buy |
| Cayman Chemical | 19110 | CBL0137 ≥95% | 1mg | $47 | 2024-03-01 | Buy |
| Cayman Chemical | 19110 | CBL0137 ≥95% | 5mg | $160 | 2024-03-01 | Buy |
| Cayman Chemical | 19110 | CBL0137 ≥95% | 10mg | $295 | 2024-03-01 | Buy |
| DC Chemicals | DC10617 | CBL0137 >98% | 250mg | $900 | 2021-12-16 | Buy |
| DC Chemicals | DC10617 | CBL0137 >98% | 1g | $1800 | 2021-12-16 | Buy |
Properties
storage temp. :Store at -20°C
solubility :≤ 2 mg/mL in ethanol; 5 mg/mL in DMSO; 5mg/mL in dimethyl formamide
form :crystalline solid
color :Off-white to light yellow
solubility :≤ 2 mg/mL in ethanol; 5 mg/mL in DMSO; 5mg/mL in dimethyl formamide
form :crystalline solid
color :Off-white to light yellow
Safety Information
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| Signal word: | Warning | |||||||
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Description
Curaxins are small molecules that simultaneously activate p53 and inhibit NF-κB without causing detectable genotoxicity. CBL0137 is a water soluble and metabolically stable curaxin that activates p53 with an EC50 value of 0.37 μM and inhibits NF-κB with an EC50 of 0.47 μM. It functionally inactivates the facilitates chromatin transcription complex, driving the effects on p53 and NF-κB and promoting cancer cell death. CBL0137 has broad anticancer activity in mice when administered orally, eradicates drug-resistant cancer stem cells, and potentiates efficacy of gemcitabine in preclinical models of pancreatic cancer.Suppliers and manufacturers
Henan Aochuang Chemical Co.,Ltd.
ATK CHEMICAL COMPANY LIMITED
BOC Sciences
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
HANGZHOU CLAP TECHNOLOGY CO.,LTD
InvivoChem
LEAP CHEM CO., LTD.
TargetMol Chemicals Inc.
Aladdin Scientific
$0.00 /1kg
1,1'-(9-(2-(isopropylamino)ethyl)-9H-carbazole-3,6-diyl)bis(ethan-1-one) CAS:1197996-80-7
1,1'-(9-(2-(isopropylamino)ethyl)-9H-carbazole-3,6-diyl)bis(ethan-1-one) CAS:1197996-80-7