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ChemicalBook >> CAS DataBase List >> Methyl 4-Fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate

Methyl 4-Fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate

Methyl 4-Fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate price.
  • $15 - $1973
  • Product name: Methyl 4-Fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate
  • CAS: 1235865-75-4
  • MF: C15H11FN2O3
  • MW: 286.26
  • EINECS:-0
  • MDL Number:MFCD28129691
  • Synonyms:abt199 int 2;ABT199 intermediate 3;ABT199 intermediates;Methyl 2-((1H-pyrrolo[2,3-b]pyrin- 5-yl)oxy)-4-fluorobenzoate;ABT-199 Intermediate;methyl 4-fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate;Venetoclax Intermediate 3;Benzoic acid, 4-fluoro-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-, methyl ester
Price35 Properties Safety Information Description
35 prices
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Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • Alichem
  • Ambeed
  • Biosynth
  • Chemenu
  • Crysdot
  • Synthonix
  • TRC
Package
  • 250mg
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  • Manufactureraablocks
  • Product numberAA000KQD
  • Product descriptionMethyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate 98%
  • Packaging5g
  • Price$35
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000KQD
  • Product descriptionMethyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate 98%
  • Packaging10g
  • Price$56
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000KQD
  • Product descriptionMethyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate ≥97%
  • Packaging1g
  • Price$15
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000KQD
  • Product descriptionMethyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate 95%
  • Packaging50g
  • Price$187
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000KQD
  • Product descriptionMethyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate 95%
  • Packaging100g
  • Price$307
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000KQD
  • Product descriptionMethyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate 98%
  • Packaging25g
  • Price$102
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberL14981
  • Product descriptionmethyl 4-fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate 97%
  • Packaging1G
  • Price$15
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberL14981
  • Product descriptionmethyl 4-fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate 97%
  • Packaging5G
  • Price$60
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberL14981
  • Product descriptionmethyl 4-fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate 97%
  • Packaging25G
  • Price$150
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ55660
  • Product descriptionMethyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate
  • Packaging50g
  • Price$794
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ55660
  • Product descriptionMethyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate
  • Packaging100g
  • Price$1430
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ55660
  • Product descriptionMethyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate
  • Packaging10g
  • Price$238
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number1235865754
  • Product descriptionMethyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate
  • Packaging25g
  • Price$1188
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number1235865754
  • Product descriptionMethyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate
  • Packaging10g
  • Price$612
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA214829
  • Product descriptionMethyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate 98+%
  • Packaging25g
  • Price$404
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA214829
  • Product descriptionMethyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate 98+%
  • Packaging5g
  • Price$145
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA000KQD Methyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate 98% 5g $35 2026-05-25 Buy
aablocks AA000KQD Methyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate 98% 10g $56 2026-05-25 Buy
aablocks AA000KQD Methyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate ≥97% 1g $15 2026-05-25 Buy
aablocks AA000KQD Methyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate 95% 50g $187 2026-05-25 Buy
aablocks AA000KQD Methyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate 95% 100g $307 2026-05-25 Buy
aablocks AA000KQD Methyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate 98% 25g $102 2026-05-25 Buy
ACHEMBLOCK L14981 methyl 4-fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate 97% 1G $15 2026-05-27 Buy
ACHEMBLOCK L14981 methyl 4-fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate 97% 5G $60 2026-05-27 Buy
ACHEMBLOCK L14981 methyl 4-fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate 97% 25G $150 2026-05-27 Buy
AK Scientific J55660 Methyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate 50g $794 2021-12-16 Buy
AK Scientific J55660 Methyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate 100g $1430 2021-12-16 Buy
AK Scientific J55660 Methyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate 10g $238 2021-12-16 Buy
Alichem 1235865754 Methyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate 25g $1188 2021-12-16 Buy
Alichem 1235865754 Methyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate 10g $612 2021-12-16 Buy
Ambeed A214829 Methyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate 98+% 25g $404 2021-12-16 Buy
Ambeed A214829 Methyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate 98+% 5g $145 2021-12-16 Buy
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Properties

Density :1.377±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
pka :13.21±0.40(Predicted)
Appearance :Light yellow to yellow Solid
InChI :InChI=1S/C15H11FN2O3/c1-20-15(19)12-3-2-10(16)7-13(12)21-11-6-9-4-5-17-14(9)18-8-11/h2-8H,1H3,(H,17,18)
InChIKey :WOXIJNIAUMZYEL-UHFFFAOYSA-N
SMILES :C(OC)(=O)C1=CC=C(F)C=C1OC1=CN=C2NC=CC2=C1
CAS DataBase Reference :1235865-75-4

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)Corrosion (GHS05)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger P280, P305+P351+P338, P310
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310 Immediately call a POISON CENTER or doctor/physician.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P501 Dispose of contents/container to..…

Description

Methyl 4-Fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate is the intermediate for ABT 199 (A112430), which is a potent and selective BCL-2 inhibitor that achieves potent antitumor activity while sparing platelets. It’s practical application is to treat chronic lymphocytic leukaemic cells and estrogen receptor-positive breast cancer.

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3-nitro-4-((tetrahydro-2H-pyran-4-yl)MethylaMino)benzenesulfonaMide ABT-199 1H-Pyrrolo[2,3-b]pyridin-5-ol, 1-[tris(1-methylethyl)silyl]- 1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine 749927-69-3 1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride tert-butyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate ARN-509 Ethyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate

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Suppliers and manufacturers

Changzhou Nuobailang Biomedical Technology Co., Ltd. NANJING ZENJI PHARMACEUTICALS EVERSHINE CHEMICAL CO., LIMITED NANJING ZENJI PHARMACEUTICALS Nanjing Lebang Pharmaceutical Technology Co., Ltd Jinan Daen Pharma Tech Co., Ltd. PharmaBlock Sciences (Nanjing), Inc. Nantong Nuotai Biomedical Technology Co., Ltd. Shanghai Boyle Chemical Co., Ltd. Adamas Reagent, Ltd.