6-(2-Chloro-4-thiazol-5-yl-phenyl)-8-ethyl-2-[4-(4-Methyl-piperazin-1-yl)-phenylaMino]-8H-pyrido[2,3-d]pyriMidin-7-one
- $37 - $2500
- Product name: 6-(2-Chloro-4-thiazol-5-yl-phenyl)-8-ethyl-2-[4-(4-Methyl-piperazin-1-yl)-phenylaMino]-8H-pyrido[2,3-d]pyriMidin-7-one
- CAS: 1286739-19-2
- MF: C29H28ClN7OS
- MW: 558.1
- EINECS:-0
- MDL Number:MFCD25976723
- Synonyms:6-(2-Chloro-4-thiazol-5-yl-phenyl)-8-ethyl-2-[4-(4-Methyl-piperazin-1-yl)-phenylaMino]-8H-pyrido[2,3-d]pyriMidin-7-one;FRAX597;Pyrido[2,3-d]pyriMidin-7(8H)-one, 6-[2-chloro-4-(5-thiazolyl)phenyl]-8-ethyl-2-[[4-(4-Methyl-1-piperazinyl)phenyl]aMino]-;6-(2-chloro-4-(thiazol-5-yl)phenyl)-8-ethyl-2-(4-(4-methylpiperazin-1-yl)phenylamino)pyrido[2,3-d]pyrimidin-7(8H)-one;6-[2-Chloro-4-(5-thiazolyl)phenyl]-8-ethyl-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one;FRAX597, >=98%;6-(2-Chloro-4-thiazol-5-yl-phenyl)-8-ethyl-2-[4-(4-Methyl-piperazin-1-yl)-phenylaMino]-8H-pyrido[2,3-d]pyriMidin-7-one USP/EP/BP;6-[2-chloro-4-(1,3-thiazol-5-yl)phenyl]-8-ethyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrido[2,3-d]pyrimidin-7-one
31 prices
Selected condition:
Brand
- AK Scientific
- Ambeed
- ApexBio Technology
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10mM(in 1mL DMSO)
- 10
- 1mg
- 2mg
- 5mg
- 50
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number2182DU
- Product descriptionCID70934541
- Packaging1mg
- Price$140
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2182DU
- Product descriptionCID70934541
- Packaging5mg
- Price$282
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA123005
- Product descriptionFRAX597 98+%
- Packaging2mg
- Price$37
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA123005
- Product descriptionFRAX597 98+%
- Packaging5mg
- Price$72
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA123005
- Product descriptionFRAX597 98+%
- Packaging10mg
- Price$108
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA123005
- Product descriptionFRAX597 98+%
- Packaging25mg
- Price$140
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA123005
- Product descriptionFRAX597 98+%
- Packaging50mg
- Price$182
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA123005
- Product descriptionFRAX597 98+%
- Packaging100mg
- Price$323
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA123005
- Product descriptionFRAX597 98+%
- Packaging250mg
- Price$645
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1162
- Product descriptionFRAX597
- Packaging5mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1162
- Product descriptionFRAX597
- Packaging10mM(in 1mL DMSO)
- Price$147
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1162
- Product descriptionFRAX597
- Packaging25mg
- Price$390
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number22205
- Product descriptionFRAX597 ≥98%
- Packaging1mg
- Price$38
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22205
- Product descriptionFRAX597 ≥98%
- Packaging5mg
- Price$166
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22205
- Product descriptionFRAX597 ≥98%
- Packaging10mg
- Price$238
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22205
- Product descriptionFRAX597 ≥98%
- Packaging25mg
- Price$547
- Updated2024-03-01
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 2182DU | CID70934541 | 1mg | $140 | 2021-12-16 | Buy |
AK Scientific | 2182DU | CID70934541 | 5mg | $282 | 2021-12-16 | Buy |
Ambeed | A123005 | FRAX597 98+% | 2mg | $37 | 2021-12-16 | Buy |
Ambeed | A123005 | FRAX597 98+% | 5mg | $72 | 2021-12-16 | Buy |
Ambeed | A123005 | FRAX597 98+% | 10mg | $108 | 2021-12-16 | Buy |
Ambeed | A123005 | FRAX597 98+% | 25mg | $140 | 2021-12-16 | Buy |
Ambeed | A123005 | FRAX597 98+% | 50mg | $182 | 2021-12-16 | Buy |
Ambeed | A123005 | FRAX597 98+% | 100mg | $323 | 2021-12-16 | Buy |
Ambeed | A123005 | FRAX597 98+% | 250mg | $645 | 2021-12-16 | Buy |
ApexBio Technology | B1162 | FRAX597 | 5mg | $120 | 2021-12-16 | Buy |
ApexBio Technology | B1162 | FRAX597 | 10mM(in 1mL DMSO) | $147 | 2021-12-16 | Buy |
ApexBio Technology | B1162 | FRAX597 | 25mg | $390 | 2021-12-16 | Buy |
Cayman Chemical | 22205 | FRAX597 ≥98% | 1mg | $38 | 2024-03-01 | Buy |
Cayman Chemical | 22205 | FRAX597 ≥98% | 5mg | $166 | 2024-03-01 | Buy |
Cayman Chemical | 22205 | FRAX597 ≥98% | 10mg | $238 | 2024-03-01 | Buy |
Cayman Chemical | 22205 | FRAX597 ≥98% | 25mg | $547 | 2024-03-01 | Buy |
Properties
Melting point :>220°C (dec.)
storage temp. :Refrigerator
solubility :DMSO (Slightly)
form :Solid
color :Yellow
storage temp. :Refrigerator
solubility :DMSO (Slightly)
form :Solid
color :Yellow
Safety Information
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Signal word: | Warning | |||||||||||||||||||||||||||||||||||
Hazard statements: |
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Precautionary statements: |
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Description
p21-activated kinases (Paks) are serine/threonine protein kinases involved in cellular signaling pathways. PAK1 is an effector of Rho GTPase. PAKs are oncogenic kinases, which have been implicated as potential therapeutic targets. FRAX 597 is a PAK1 inhibitor that can reduce pancreatic cancer growth when used with Gemcitabine (G305000), an antineoplastic agent.Related product price
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$28-4173.5
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