H-TYR-LEU-TYR-GLN-TRP-LEU-GLY-ALA-PRO-VAL-PRO-TYR-PRO-ASP-PRO-LEU-GLA-PRO-ARG-ARG-GLA-VAL-CYS-GLA-LEU-ASN-PRO-ASP-CYS-ASP-GLU-LEU-ALA-ASP-HIS-ILE-GLY-PHE-GLN-GLU-ALA-TYR-ARG-ARG-PHE-TYR-GLY-PRO-VAL-OH
|
- $459 - $5263.2
- Product name: H-TYR-LEU-TYR-GLN-TRP-LEU-GLY-ALA-PRO-VAL-PRO-TYR-PRO-ASP-PRO-LEU-GLA-PRO-ARG-ARG-GLA-VAL-CYS-GLA-LEU-ASN-PRO-ASP-CYS-ASP-GLU-LEU-ALA-ASP-HIS-ILE-GLY-PHE-GLN-GLU-ALA-TYR-ARG-ARG-PHE-TYR-GLY-PRO-VAL-OH
- CAS: 136461-80-8
- MF: C269H381N67O82S2
- MW: 5929.43
- EINECS:
- MDL Number:MFCD00147801
- Synonyms:TYR-LEU-TYR-GLN-TRP-LEU-GLY-ALA-PRO-VAL-PRO-TYR-PRO-ASP-PRO-LEU-GLA-PRO-ARG-ARG-GLA-VAL-CYS-GLA-LEU-ASN-PRO-ASP-CYS-ASP-GLU-LEU-ALA-ASP-HIS-ILE-GLY-PHE-GLN-GLU-ALA-TYR-ARG-ARG-PHE-TYR-GLY-PRO-VAL (DISULFIDE BRIDGE: CYS23-CYS29);TYR-LEU-TYR-GLN-TRP-LEU-GLY-ALA-PRO-VAL-PRO-TYR-PRO-ASP-PRO-LEU-GLA-PRO-ARG-ARG-GLA-VAL-CYS-GLA-LEU-ASN-PRO-ASP-CYS-ASP-GLU-LEU-ALA-ASP-HIS-ILE-GLY-PHE-GLN-GLU-ALA-TYR-ARG-ARG-PHE-TYR-GLY-PRO-VAL: YLYQWLGAPVPYPDPL-GLA-PRR-GLA-VC-GLA-LNPDCDELADHIGFQEAYRRFY;YLYQWLGAPVPYPDPL-Gla-PRR-Gla-VC-Gla-LNPDCDELADHIGFQEAYRRFYGPV(Gla=γ-CarboxyglutamicAcid:Disulfidebridge:23-29);Tyr-Leu-Tyr-Gln-Trp-Leu-Gly-Ala-Pro-Val-Pro-Tyr-Pro-Asp-Pro-Leu-Gla-Pro-Arg-Arg-Gla-Val-Cys-Gla-Leu-Asn-Pro-Asp-Cys-Asp-Glu-Leu-Ala-Asp-His-Ile-Gly-Phe-Gln-Glu-Ala-Tyr-Arg-Arg-Phe-Tyr-Gly-Pro-Val(Disu;OSTEOCALCIN (HUMAN, GLA17,21,24);OSTEOCALCIN (1-49) (HUMAN);TYR-LEU-TYR-GLN-TRP-LEU-GLY-ALA-PRO-VAL-PRO-TYR-PRO-ASP-PRO-LEU-GLA-PRO-ARG-ARG-GLA-VAL-CYS-GLA-LEU-ASN-PRO-ASP-CYS-ASP-GLU-LEU-ALA-ASP-HIS-ILE-GLY-PHE-GLN-GLU-ALA-TYR-ARG-ARG-PHE-TYR-GLY-PRO-VAL;YLYQWLGAPVPYPDPL-GLA-PRR-GLA-VC-GLA-LNPDCDELADHIGFQEAYRRFYGPV
7 prices
Selected condition：
Brand
- Biorbyt Ltd
- Cayman Chemical
- Sigma-Aldrich
Package
- 100μg
- 500μg
- 1mg
- 5mg
- 10mg
- ManufacturerBiorbyt Ltd
- Product numberorb372957
- Product descriptionOsteocalcin (1-49) > 95%
- Packaging1mg
- Price$1412.7
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb372957
- Product descriptionOsteocalcin (1-49) > 95%
- Packaging5mg
- Price$3512.2
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb372957
- Product descriptionOsteocalcin (1-49) > 95%
- Packaging10mg
- Price$5263.2
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number24723
- Product descriptionOsteocalcin (1-49) (human) (trifluoroacetate salt) ≥95%
- Packaging100μg
- Price$459
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number24723
- Product descriptionOsteocalcin (1-49) (human) (trifluoroacetate salt) ≥95%
- Packaging500μg
- Price$1148
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberO5761
- Product descriptionOsteocalcin fragment 1-49 Human ≥94%(HPLC),solid
- Packaging500μg
- Price$878
- Updated2025-07-31
- Buy
- ManufacturerSigma-Aldrich
- Product numberO5761
- Product descriptionOsteocalcin fragment 1-49 Human ≥94% (HPLC), solid
- Packaging1mg
- Price$1690
- Updated2025-07-31
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Biorbyt Ltd | orb372957 | Osteocalcin (1-49) > 95% | 1mg | $1412.7 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb372957 | Osteocalcin (1-49) > 95% | 5mg | $3512.2 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb372957 | Osteocalcin (1-49) > 95% | 10mg | $5263.2 | 2021-12-16 | Buy |
| Cayman Chemical | 24723 | Osteocalcin (1-49) (human) (trifluoroacetate salt) ≥95% | 100μg | $459 | 2024-03-01 | Buy |
| Cayman Chemical | 24723 | Osteocalcin (1-49) (human) (trifluoroacetate salt) ≥95% | 500μg | $1148 | 2024-03-01 | Buy |
| Sigma-Aldrich | O5761 | Osteocalcin fragment 1-49 Human ≥94%(HPLC),solid | 500μg | $878 | 2025-07-31 | Buy |
| Sigma-Aldrich | O5761 | Osteocalcin fragment 1-49 Human ≥94% (HPLC), solid | 1mg | $1690 | 2025-07-31 | Buy |
Properties
storage temp. :-20°C
solubility :Formic Acid: 1 mg/ml
form :solid
Sequence :Tyr-Leu-Tyr-Gln-Trp-Leu-Gly-Ala-Pro-Val-Pro-Tyr-Pro-Asp-Pro-Leu-{Gla}- Pro-Arg-Arg-{Gla}-Val-Cys-{Gla}-Leu-Asn-Pro-Asp-Cys-Asp-Glu-Leu-Ala-Asp-His-Ile-Gly-Phe-Gln-Glu-Ala-Tyr-Arg-Arg-Phe-Tyr-Gly-Pro-Val (Disulfide bridge:Cys23-Cys29)
solubility :Formic Acid: 1 mg/ml
form :solid
Sequence :Tyr-Leu-Tyr-Gln-Trp-Leu-Gly-Ala-Pro-Val-Pro-Tyr-Pro-Asp-Pro-Leu-{Gla}- Pro-Arg-Arg-{Gla}-Val-Cys-{Gla}-Leu-Asn-Pro-Asp-Cys-Asp-Glu-Leu-Ala-Asp-His-Ile-Gly-Phe-Gln-Glu-Ala-Tyr-Arg-Arg-Phe-Tyr-Gly-Pro-Val (Disulfide bridge:Cys23-Cys29)
Safety Information
| Symbol(GHS): | ||||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | ||||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
Osteocalcin (1-49) is a non-collagenous peptide that is secreted by osteoblasts and odontoblasts and comprises 1-2% of the total protein in bone. Secretion of osteocalcin (1-49) is stimulated by 1,25-dihydroxy vitamin D and plasma levels increase in diseases that induce dysregulated bone turnover such as osteoporosis, Paget''s disease, and primary hyperparathyroidism. Osteocalcin (1-49) is positively correlated with insulin sensitivity and negatively correlated with high blood glucose levels in women. In vitro, osteocalcin induces chemotaxis of MDA-MB-231 breast cancer cells, human peripheral blood monocytes, and rat osteosarcoma cells with osteoblast-like characteristics. It is also expressed by vascular smooth muscle cells (VSMCs) displaying an osteoblast-like phenotype and has been positively associated with calcification of aortic tissue and heart valves in humans.Related product price
- H-PHE-TYR-GLY-PRO-VAL-OH
$44.9-863.3 - H-GLY-PHE-GLN-GLU-ALA-TYR-ARG-ARG-PHE-TYR-GLY-PRO-VAL-OH
$612.44 - BENZYL ISOCYANIDE
$81.65-2194.5
