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ChemicalBook >> CAS DataBase List >> (S)-1-((5-chloropyridin-3-yl)methyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one

(S)-1-((5-chloropyridin-3-yl)methyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one

(S)-1-((5-chloropyridin-3-yl)methyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one price.
  • $46 - $8880
  • Product name: (S)-1-((5-chloropyridin-3-yl)methyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one
  • CAS: 1523406-39-4
  • MF: C19H21ClF3N5O2
  • MW: 443.85
  • EINECS:
  • MDL Number:MFCD28411361
  • Synonyms:(S)-1-((5-chloropyridin-3-yl)methyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one;SAR-405;(S)-1-((5-Chloropyridin-3-yl)methyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydr;SAR-405;SAR 405;CS-2552;4H-Pyrimido[1,2-a]pyrimidin-4-one, 9-[(5-chloro-3-pyridinyl)methyl]-6,7,8,9-tetrahydro-2-[(3R)-3-methyl-4-morpholinyl]-8-(trifluoromethyl)-, (8S)-;(8S)-9-[(5-Chloro-3-pyridinyl)methyl]-6,7,8,9-tetrahydro-2-[(3R)-3-methyl-4-morpholinyl]-8-(trifluoromethyl)-4H-pyrimido[1,2-a]pyrimidin-4-one;(S)-9-((5-Chloropyridin-3-yl)methyl)-2-((R)-3-methylmorpholino)-8-(trifluoromethyl)-6,7,8,9-tetrahydro-4H-pyrimido[1,2-a]pyrimidin-4-one
26 prices
Selected condition:
Brand
  • AK Scientific
  • ApexBio Technology
  • Apolloscientific
  • Axon Medchem
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • TRC
Package
  • 500μg
  • 1mg
  • 10mM(in 1mL DMSO)
  • 2mg
  • 2.5mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number3901DW
  • Product descriptionCID72709209
  • Packaging1mg
  • Price$209
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3901DW
  • Product descriptionCID72709209
  • Packaging5mg
  • Price$313
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8883
  • Product descriptionSAR405
  • Packaging10mM(in 1mL DMSO)
  • Price$127
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0016
  • Product descriptionSAR405 98%
  • Packaging5mg
  • Price$174
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0016
  • Product descriptionSAR405 98%
  • Packaging10mg
  • Price$305
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0016
  • Product descriptionSAR405 98%
  • Packaging25mg
  • Price$595
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2716
  • Product descriptionSAR405 98%
  • Packaging5mg
  • Price$137.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb611421
  • Product descriptionSAR405
  • Packaging5mg
  • Price$314.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb611421
  • Product descriptionSAR405
  • Packaging10mg
  • Price$462.4
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb611421
  • Product descriptionSAR405
  • Packaging25mg
  • Price$652.8
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number16979
  • Product descriptionSAR405 ≥98%
  • Packaging500μg
  • Price$46
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16979
  • Product descriptionSAR405 ≥98%
  • Packaging1mg
  • Price$83
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16979
  • Product descriptionSAR405 ≥98%
  • Packaging5mg
  • Price$162
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5756
  • Product descriptionSAR405 99.52%
  • Packaging2mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5756
  • Product descriptionSAR405 99.52%
  • Packaging5mg
  • Price$130
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5756
  • Product descriptionSAR405 99.52%
  • Packaging10mg
  • Price$230
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3901DW CID72709209 1mg $209 2021-12-16 Buy
AK Scientific 3901DW CID72709209 5mg $313 2021-12-16 Buy
ApexBio Technology A8883 SAR405 10mM(in 1mL DMSO) $127 2021-12-16 Buy
Apolloscientific BISN0016 SAR405 98% 5mg $174 2021-12-16 Buy
Apolloscientific BISN0016 SAR405 98% 10mg $305 2021-12-16 Buy
Apolloscientific BISN0016 SAR405 98% 25mg $595 2021-12-16 Buy
Axon Medchem Axon2716 SAR405 98% 5mg $137.5 2021-12-16 Buy
Biorbyt Ltd orb611421 SAR405 5mg $314.5 2021-12-16 Buy
Biorbyt Ltd orb611421 SAR405 10mg $462.4 2021-12-16 Buy
Biorbyt Ltd orb611421 SAR405 25mg $652.8 2021-12-16 Buy
Cayman Chemical 16979 SAR405 ≥98% 500μg $46 2024-03-01 Buy
Cayman Chemical 16979 SAR405 ≥98% 1mg $83 2024-03-01 Buy
Cayman Chemical 16979 SAR405 ≥98% 5mg $162 2024-03-01 Buy
ChemScene CS-5756 SAR405 99.52% 2mg $90 2021-12-16 Buy
ChemScene CS-5756 SAR405 99.52% 5mg $130 2021-12-16 Buy
ChemScene CS-5756 SAR405 99.52% 10mg $230 2021-12-16 Buy

Properties

Boiling point :526.5±60.0 °C(Predicted)
Density :1.51±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥22.19 mg/mL in DMSO; insoluble in H2O; ≥32.25 mg/mL in EtOH with ultrasonic
form :Powder
pka :3.29±0.20(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

SAR 405 is an anticancer agent and a phosphoinositide 3-kinase (PI3K) inhibitor.