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ChemicalBook >> CAS DataBase List >> 1H-INDOLE-5-CARBOXAMIDE, 97%

1H-INDOLE-5-CARBOXAMIDE, 97%

1H-INDOLE-5-CARBOXAMIDE, 97% price.
  • $37 - $2148.3
  • Product name: 1H-INDOLE-5-CARBOXAMIDE, 97%
  • CAS: 1670-87-7
  • MF: C9H8N2O
  • MW: 160.17
  • EINECS:
  • MDL Number:MFCD07779486
  • Synonyms:1H-INDOLE-5-CARBOXAMIDE, 97%;SD-169;1H-Indole-5-carboxamide(9CI);5-(AMinocarbonyl)-1H-indole;5-CarbaMoylindole;p38 MAP Kinase Inhibitor VII, SD-169 ;5-(Aminocarbonyl)-1H-indole, 5-Carbamoylindole, 5-Carboxamidoindole;p38 MAP Kinase Inhibitor VII, SD-169 - CAS 1670-87-7 - Calbiochem
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  • Adipogen Life Sciences
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Axon Medchem
  • Cayman Chemical
  • ChemScene
  • CSNpharm
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
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  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1079-M010
  • Product descriptionSD-169 ≥95%
  • Packaging10mg
  • Price$81
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN1079
  • Product descriptionSD169
  • Packaging50mg
  • Price$260
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA538658
  • Product description1H-indole-5-carboxamide 97%
  • Packaging100mg
  • Price$46
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA538658
  • Product description1H-indole-5-carboxamide 97%
  • Packaging250mg
  • Price$71
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA538658
  • Product description1H-indole-5-carboxamide 97%
  • Packaging1g
  • Price$194
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000301
  • Product description1H-INDOLE-5-CARBOXAMIDE 95.00%
  • Packaging1MG
  • Price$166.95
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000301
  • Product description1H-INDOLE-5-CARBOXAMIDE 95.00%
  • Packaging1G
  • Price$716.1
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000301
  • Product description1H-INDOLE-5-CARBOXAMIDE 95.00%
  • Packaging10G
  • Price$2148.3
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC5850
  • Product descriptionSD169
  • Packaging10mg
  • Price$68
  • Updated2021-12-16
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  • ManufacturerAxon Medchem
  • Product numberAxon1357
  • Product descriptionSD169 99%
  • Packaging25mg
  • Price$198
  • Updated2021-12-16
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  • ManufacturerCayman Chemical
  • Product number14156
  • Product descriptionSD 169 ≥97%
  • Packaging5mg
  • Price$37
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14156
  • Product descriptionSD 169 ≥97%
  • Packaging10mg
  • Price$62
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14156
  • Product descriptionSD 169 ≥97%
  • Packaging25mg
  • Price$142
  • Updated2024-03-01
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  • ManufacturerChemScene
  • Product numberCS-W016161
  • Product descriptionSD-169 99.44%
  • Packaging1g
  • Price$120
  • Updated2021-12-16
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  • ManufacturerChemScene
  • Product numberCS-W016161
  • Product descriptionSD-169 99.44%
  • Packaging5g
  • Price$600
  • Updated2021-12-16
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN27555
  • Product descriptionSD-169
  • Packaging50mg
  • Price$140
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences SYN-1079-M010 SD-169 ≥95% 10mg $81 2021-12-16 Buy
AK Scientific SYN1079 SD169 50mg $260 2021-12-16 Buy
Ambeed A538658 1H-indole-5-carboxamide 97% 100mg $46 2021-12-16 Buy
Ambeed A538658 1H-indole-5-carboxamide 97% 250mg $71 2021-12-16 Buy
Ambeed A538658 1H-indole-5-carboxamide 97% 1g $194 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000301 1H-INDOLE-5-CARBOXAMIDE 95.00% 1MG $166.95 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000301 1H-INDOLE-5-CARBOXAMIDE 95.00% 1G $716.1 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000301 1H-INDOLE-5-CARBOXAMIDE 95.00% 10G $2148.3 2021-12-16 Buy
ApexBio Technology C5850 SD169 10mg $68 2021-12-16 Buy
Axon Medchem Axon1357 SD169 99% 25mg $198 2021-12-16 Buy
Cayman Chemical 14156 SD 169 ≥97% 5mg $37 2024-03-01 Buy
Cayman Chemical 14156 SD 169 ≥97% 10mg $62 2024-03-01 Buy
Cayman Chemical 14156 SD 169 ≥97% 25mg $142 2024-03-01 Buy
ChemScene CS-W016161 SD-169 99.44% 1g $120 2021-12-16 Buy
ChemScene CS-W016161 SD-169 99.44% 5g $600 2021-12-16 Buy
CSNpharm CSN27555 SD-169 50mg $140 2021-12-16 Buy

Properties

Melting point :159-163 °C
Boiling point :457.6±18.0 °C(Predicted)
Density :1.328±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :DMSO (Slightly), Methanol (Slightly)
pka :16.25±0.30(Predicted)
form :Off-white solid
color :Off-White to Light Purple

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

SD 169 is a selective ATP competitive inhibitor of the MAP kinases p38α (IC50 = 3.2 nM) and p38β (IC50 = 122 nM). It has no inhibitory effect against a panel of other kinases, including p38γ MAP kinase, ERK2, JNK-1, and MAPKAPK-2, when tested in vitro at 50 μM. SD 169 is orally active, significantly reducing p38 MAP kinase expression in T cells of nonobese diabetic mice when delivered in chow at 600 mg/kg. In this model, SD 169 also reduced the incidence of diabetes, lowered blood glucose, and improved glucose homeostasis. SD 169 also enhances axonal regeneration after sciatic nerve crush injury in rats, when given by gavage (30 mg/kg) before and after nerve damage.

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