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ChemicalBook >> CAS DataBase List >> Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S,5R,6S)- (9CI)

Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S,5R,6S)- (9CI)

Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S,5R,6S)- (9CI) price.
  • $33 - $9750
  • Product name: Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S,5R,6S)- (9CI)
  • CAS: 176199-48-7
  • MF: C8H11NO4
  • MW: 185.18
  • EINECS:
  • MDL Number:
  • Synonyms:Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S,5R,6S)- (9CI);Eglumegad;Eglumetad;LY 354740;(1S,2S,5R,6S)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid;Bicyclo[3.1.0]hexane-2,6-dicarboxylicacid, 2-aMino-, [1S-(1a,2b,5a,6a)]-;Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid,2-amino-,(1S,2S,5R,6S)-;Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S...
27 prices
Selected condition:
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 2.5MG
  • 10
  • 1mg
  • 5mg
  • 25mg
  • 50
  • 10MG
  • 50MG
  • 500mg
  • 1g
  • ManufacturerAK Scientific
  • Product number3045CB
  • Product descriptionEglumetad
  • Packaging5mg
  • Price$214
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA163426
  • Product description(1S,2S,5R,6S)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylicacid 98+%
  • Packaging1g
  • Price$1405
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0006791
  • Product descriptionLY-354740 95.00%
  • Packaging2.5MG
  • Price$314
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0006791
  • Product descriptionLY-354740 95.00%
  • Packaging10MG
  • Price$794.36
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0006791
  • Product descriptionLY-354740 95.00%
  • Packaging50MG
  • Price$1441.97
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7328
  • Product descriptionLY354740
  • Packaging5mg
  • Price$118
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7328
  • Product descriptionLY354740
  • Packaging10mg
  • Price$181
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS458570
  • Product description(1S,2S,5R,6S)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylicacid ≥98%
  • Packaging1g
  • Price$1391
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number24215
  • Product descriptionLY354740 ≥95%
  • Packaging1mg
  • Price$33
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number24215
  • Product descriptionLY354740 ≥95%
  • Packaging5mg
  • Price$106
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number24215
  • Product descriptionLY354740 ≥95%
  • Packaging10mg
  • Price$160
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5052
  • Product descriptionEglumegad >98.0%
  • Packaging5mg
  • Price$102
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5052
  • Product descriptionEglumegad >98.0%
  • Packaging10mg
  • Price$144
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5052
  • Product descriptionEglumegad >98.0%
  • Packaging50mg
  • Price$600
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002954
  • Product descriptionLY354740 98+%
  • Packaging5mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002954
  • Product descriptionLY354740 98+%
  • Packaging10mg
  • Price$84
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3045CB Eglumetad 5mg $214 2021-12-16 Buy
Ambeed A163426 (1S,2S,5R,6S)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylicacid 98+% 1g $1405 2021-12-16 Buy
American Custom Chemicals Corporation API0006791 LY-354740 95.00% 2.5MG $314 2021-12-16 Buy
American Custom Chemicals Corporation API0006791 LY-354740 95.00% 10MG $794.36 2021-12-16 Buy
American Custom Chemicals Corporation API0006791 LY-354740 95.00% 50MG $1441.97 2021-12-16 Buy
ApexBio Technology B7328 LY354740 5mg $118 2021-12-16 Buy
ApexBio Technology B7328 LY354740 10mg $181 2021-12-16 Buy
Arctom AS458570 (1S,2S,5R,6S)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylicacid ≥98% 1g $1391 2021-12-16 Buy
Cayman Chemical 24215 LY354740 ≥95% 1mg $33 2024-03-01 Buy
Cayman Chemical 24215 LY354740 ≥95% 5mg $106 2024-03-01 Buy
Cayman Chemical 24215 LY354740 ≥95% 10mg $160 2024-03-01 Buy
ChemScene CS-5052 Eglumegad >98.0% 5mg $102 2021-12-16 Buy
ChemScene CS-5052 Eglumegad >98.0% 10mg $144 2021-12-16 Buy
ChemScene CS-5052 Eglumegad >98.0% 50mg $600 2021-12-16 Buy
Crysdot CD31002954 LY354740 98+% 5mg $60 2021-12-16 Buy
Crysdot CD31002954 LY354740 98+% 10mg $84 2021-12-16 Buy

Properties

Melting point :270-271 °C
Boiling point :376.4±32.0 °C(Predicted)
Density :1.569
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :H2O : 6.33 mg/mL (34.18 mM; Need ultrasonic and warming)
form :Powder
pka :2.06±0.40(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

LY 354740 is a highly selective and potent mGluR-2/3 (group II mGlu receptor) agonist. LY 354740 has been shown to be a conformationally constrained analog of glutamate with the ability to decrease forskolin-stimulated cAMP formation by more than 90%. Recent studies have found that activation of presynaptic metabotropic mGluR-2/3 induces long lasting inhibition of P/Q-type Ca2+ channels and the cAMP/protein kinase A pathway.

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