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ChemicalBook >> CAS DataBase List >> 1-(4-Aminophenyl)-4-methyl-7,8-methylenedioxy-5H-2,3-benzodiazepine hydrochloride

1-(4-Aminophenyl)-4-methyl-7,8-methylenedioxy-5H-2,3-benzodiazepine hydrochloride

1-(4-Aminophenyl)-4-methyl-7,8-methylenedioxy-5H-2,3-benzodiazepine hydrochloride price.
  • $146 - $1526.4
  • Product name: 1-(4-Aminophenyl)-4-methyl-7,8-methylenedioxy-5H-2,3-benzodiazepine hydrochloride
  • CAS: 192065-56-8
  • MF: C17H15N3O2HCl
  • MW: 329.78
  • EINECS:
  • MDL Number:MFCD00153803
  • Synonyms:GYKI 52466 (HCl salt);GYKI 52466 hydrochloride,1-(4-Aminophenyl)-4-methyl-7,8-methylenedioxy-5H-2,3-benzodiazepine hydrochloride;4-(8-Methyl-9H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d][1,2]diazepin-5-yl)aniline hydrochloride;1-(4-AMINOPHENYL)-4-METHYL-7,8-METHYLENEDIOXY-5H-2,3-BENZODIAZEPINE HYDROCHLORIDE;GYKI 52466 hydrochloride solid;Benzenamine, 4-(8-methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)-, hydrochloride (1:1)
Price16 Properties Safety Information Description
16 prices
Selected condition：
Brand
  • aablocks
  • Alichem
  • American Custom Chemicals Corporation
  • Biosynth
  • Cayman Chemical
  • Crysdot
  • Sigma-Aldrich
Package
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • Manufactureraablocks
  • Product numberAA002FJK
  • Product description4-(8-Methyl-9H-[1，3]dioxolo[4'，5':4，5]benzo[1，2-d][1，2]diazepin-5-yl)aniline hydrochloride ≥98%
  • Packaging10mg
  • Price$146
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA002FJK
  • Product description4-(8-Methyl-9H-[1，3]dioxolo[4'，5':4，5]benzo[1，2-d][1，2]diazepin-5-yl)aniline hydrochloride ≥98%
  • Packaging50mg
  • Price$614
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA002FJK
  • Product description4-(8-Methyl-9H-[1，3]dioxolo[4'，5':4，5]benzo[1，2-d][1，2]diazepin-5-yl)aniline hydrochloride ≥98%
  • Packaging25mg
  • Price$345
  • Updated2026-05-28
  • Buy
  • ManufacturerAlichem
  • Product number192065568
  • Product description4-(8-Methyl-9H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d][1,2]diazepin-5-yl)anilinehydrochloride
  • Packaging100mg
  • Price$1526.4
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCBL0000325
  • Product descriptionGYKI 52466 HYDROCHLORIDE 95.00%
  • Packaging100MG
  • Price$1517.16
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCBL0000325
  • Product descriptionGYKI 52466 HYDROCHLORIDE 95.00%
  • Packaging10MG
  • Price$680.36
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCBL0000325
  • Product descriptionGYKI 52466 HYDROCHLORIDE 95.00%
  • Packaging25MG
  • Price$866.51
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth
  • Product numberSHA06556
  • Product descriptionGyki 52466 hydrochloride
  • Packaging50mg
  • Price$953
  • Updated2026-06-05
  • Buy
  • ManufacturerBiosynth
  • Product numberSHA06556
  • Product descriptionGyki 52466 hydrochloride
  • Packaging100mg
  • Price$1325
  • Updated2026-06-05
  • Buy
  • ManufacturerCayman Chemical
  • Product number34418
  • Product descriptionGYKI 52466 (hydrochloride) ≥98%
  • Packaging50mg
  • Price$614
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number34418
  • Product descriptionGYKI 52466 (hydrochloride) ≥98%
  • Packaging10mg
  • Price$146
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number34418
  • Product descriptionGYKI 52466 (hydrochloride) ≥98%
  • Packaging25mg
  • Price$345
  • Updated2026-04-30
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11175825
  • Product description4-(8-Methyl-9H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d][1,2]diazepin-5-yl)anilinehydrochloride 95+%
  • Packaging100mg
  • Price$1429
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberG119
  • Product descriptionGYKI 52466 hydrochloride solid
  • Packaging25mg
  • Price$482
  • Updated2026-04-30
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberG119
  • Product descriptionGYKI 52466 hydrochloride solid
  • Packaging10mg
  • Price$192
  • Updated2026-04-30
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberG119
  • Product descriptionGYKI 52466 hydrochloride solid
  • Packaging100mg
  • Price$1050
  • Updated2026-04-30
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA002FJK 4-(8-Methyl-9H-[1，3]dioxolo[4'，5':4，5]benzo[1，2-d][1，2]diazepin-5-yl)aniline hydrochloride ≥98% 10mg $146 2026-05-28 Buy
aablocks AA002FJK 4-(8-Methyl-9H-[1，3]dioxolo[4'，5':4，5]benzo[1，2-d][1，2]diazepin-5-yl)aniline hydrochloride ≥98% 50mg $614 2026-05-28 Buy
aablocks AA002FJK 4-(8-Methyl-9H-[1，3]dioxolo[4'，5':4，5]benzo[1，2-d][1，2]diazepin-5-yl)aniline hydrochloride ≥98% 25mg $345 2026-05-28 Buy
Alichem 192065568 4-(8-Methyl-9H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d][1,2]diazepin-5-yl)anilinehydrochloride 100mg $1526.4 2021-12-16 Buy
American Custom Chemicals Corporation CBL0000325 GYKI 52466 HYDROCHLORIDE 95.00% 100MG $1517.16 2021-12-16 Buy
American Custom Chemicals Corporation CBL0000325 GYKI 52466 HYDROCHLORIDE 95.00% 10MG $680.36 2021-12-16 Buy
American Custom Chemicals Corporation CBL0000325 GYKI 52466 HYDROCHLORIDE 95.00% 25MG $866.51 2021-12-16 Buy
Biosynth SHA06556 Gyki 52466 hydrochloride 50mg $953 2026-06-05 Buy
Biosynth SHA06556 Gyki 52466 hydrochloride 100mg $1325 2026-06-05 Buy
Cayman Chemical 34418 GYKI 52466 (hydrochloride) ≥98% 50mg $614 2026-04-30 Buy
Cayman Chemical 34418 GYKI 52466 (hydrochloride) ≥98% 10mg $146 2026-04-30 Buy
Cayman Chemical 34418 GYKI 52466 (hydrochloride) ≥98% 25mg $345 2026-04-30 Buy
Crysdot CD11175825 4-(8-Methyl-9H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d][1,2]diazepin-5-yl)anilinehydrochloride 95+% 100mg $1429 2021-12-16 Buy
Sigma-Aldrich G119 GYKI 52466 hydrochloride solid 25mg $482 2026-04-30 Buy
Sigma-Aldrich G119 GYKI 52466 hydrochloride solid 10mg $192 2026-04-30 Buy
Sigma-Aldrich G119 GYKI 52466 hydrochloride solid 100mg $1050 2026-04-30 Buy

Properties

storage temp. :Sealed in dry,Room Temperature
solubility :DMSO: soluble0.39mg/mL
form :solid
color :yellow
InChI :1S/C17H15N3O2.ClH/c1-10-6-12-7-15-16(22-9-21-15)8-14(12)17(20-19-10)11-2-4-13(18)5-3-11;/h2-5,7-8H,6,9,18H2,1H3;1H
InChIKey :RUBSCPARMVJNKX-UHFFFAOYSA-N
SMILES :Cl[H].CC1=NN=C(c2ccc(N)cc2)c3cc4OCOc4cc3C1

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

GYKI 52466 hydrochloride has been used as an α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor selective antagonist in cell viability assays to evaluate the specificity of kainate (KA) effect on cerebellar granule cells (CGCs). It has also been used as an AMPA blocker to study the function of glutamate in neuroadapted sindbis virus (NSV) -induced motor neuron death.

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Suppliers and manufacturers

BOC Sciences Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. Sigma-Aldrich Shanghai EFE Biological Technology Co., Ltd. Shanghai Han-Xiang Chemical Co., Ltd. HUNAN CHEMFISH SCIENTIFIC CO.,LTD Energy Chemical TargetMol Chemicals Inc. Huai Hua Binfengchem Co., Ltd Chengdu Peter-like Biotechnology Co., Ltd.