PAMAM dendrimer generation&
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- $187 - $717
- Product name: PAMAM dendrimer generation&
- CAS: 192948-77-9
- MF: C494H800N122Na64O188
- MW: 12927.69
- EINECS:
- MDL Number:MFCD00197936
- Synonyms:pamam dendrimer, generation 3.5 solution;PAMAM dendrimer, ethylenediamine core, generation 3.5 solution;PAMAM dendriMer, ethylenediaMine core, generation 3.5 solution 10 wt. % in Methanol;STARBURST (PAMAM) DENDRIMER, GENERATION 3.5, 10% SOLUTION IN METHYL ALCOHOL;PAMAM dendrimer generation&
6 prices
Selected condition：
Brand
- aablocks
- Cayman Chemical
- Sigma-Aldrich
Package
- 200mg
- 500mg
- 1g
- 2g
- 2.5g
- 10g
- Manufactureraablocks
- Product numberAA00ASBR
- Product descriptionPAMAM dendrimer, ethylenediamine core generation 3.5 10
- Packaging200mg
- Price$187
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ASBR
- Product descriptionPAMAM dendrimer, ethylenediamine core generation 3.5 10wt.%inmethanol
- Packaging2g
- Price$207
- Updated2026-05-28
- Buy
- ManufacturerCayman Chemical
- Product number39108
- Product descriptionPAMAM Dendrimer G3.5 Carboxylate (sodium salt) (water solution)
- Packaging500mg
- Price$237
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number39108
- Product descriptionPAMAM Dendrimer G3.5 Carboxylate (sodium salt) (water solution)
- Packaging1g
- Price$450
- Updated2026-04-30
- Buy
- ManufacturerSigma-Aldrich
- Product number412430
- Product descriptionPAMAM dendrimer, ethylenediamine core, generation 3.5 solution 10 wt. % in methanol
- Packaging10g
- Price$717
- Updated2026-04-30
- Buy
- ManufacturerSigma-Aldrich
- Product number412430
- Product descriptionPAMAM dendrimer, ethylenediamine core, generation 3.5 solution 10 wt. % in methanol
- Packaging2.5g
- Price$221
- Updated2026-04-30
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00ASBR | PAMAM dendrimer, ethylenediamine core generation 3.5 10 | 200mg | $187 | 2026-05-28 | Buy |
| aablocks | AA00ASBR | PAMAM dendrimer, ethylenediamine core generation 3.5 10wt.%inmethanol | 2g | $207 | 2026-05-28 | Buy |
| Cayman Chemical | 39108 | PAMAM Dendrimer G3.5 Carboxylate (sodium salt) (water solution) | 500mg | $237 | 2026-04-30 | Buy |
| Cayman Chemical | 39108 | PAMAM Dendrimer G3.5 Carboxylate (sodium salt) (water solution) | 1g | $450 | 2026-04-30 | Buy |
| Sigma-Aldrich | 412430 | PAMAM dendrimer, ethylenediamine core, generation 3.5 solution 10 wt. % in methanol | 10g | $717 | 2026-04-30 | Buy |
| Sigma-Aldrich | 412430 | PAMAM dendrimer, ethylenediamine core, generation 3.5 solution 10 wt. % in methanol | 2.5g | $221 | 2026-04-30 | Buy |
Properties
Boiling point :65 °C
Density :0.81 g/mL at 25 °C
refractive index :n20/D 1.346
Flash point :52 °F
storage temp. :2-8°C
solubility :Water: Soluble
form :10 wt.% in methanol
Density :0.81 g/mL at 25 °C
refractive index :n
Flash point :52 °F
storage temp. :2-8°C
solubility :Water: Soluble
form :10 wt.% in methanol
Safety Information
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| Signal word: | Danger | |||||||||||||||||||||
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Description
PAMAM dendrimer G3.5 carboxylate (PAMAM G3.5) is a polyamidoamine (PAMAM) dendrimer with carboxylate termini that has been used as a drug delivery system in vitro and in vivo.1,2 It is approximately 66.1 Å in diameter in water and has 48 surface groups.3 PAMAM G3.5 is active against E. coli (IC50 = 22 mg/ml) and increases the mitochondrial membrane potential of isolated rat liver mitochondria when used at concentrations ranging from 10 to 50 µM.4,5 Unlike amine-terminated PAMAM G4.0, PAMAM G3.5 (20 µM) is not toxic to zebrafish embryos.6 A fluorescently labeled form of PAMAM G3.5 enters Caco-2 cells via dynamin-, clathrin-, and caveolin-mediated endocytosis.7 Conjugates of PAMAM G3.5 with the active fragment of the DNA cross-linking agent oxaliplatin (Item No. 13106) are cytotoxic to A2780 ovarian, MCF-7 breast, and Caco-2 colon cancer cells and BJ fibroblasts (IC50s = 0.08, 4.1, 0.39, and 3 µM, respectively).1 PAMAM G3.5 in complex with the topoisomerase I inhibitor camptothecin (Item No. 11694) increases the oral bioavailability of camptothecin in mice.2WARNING This product is not for human or veterinary use.Related product price
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Suppliers and manufacturers
Shanghai Macklin Biochemical Co.,Ltd.
Sigma-Aldrich
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Zhengzhou Acme Chemical Co., Ltd.
Henan Alpha Chemical Co., Ltd.
Henan Alfa Chemical Co., Ltd
Beijing Aomi Jiade Pharmaceutical Technology Co., Ltd
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd
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Jilin Chinese Academy of Sciences-yanshen Technology