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ChemicalBook >> CAS DataBase List >> pamam dendrimer, generation 4.5 solution

pamam dendrimer, generation 4.5 solution

pamam dendrimer, generation 4.5 solution price.
  • $351 - $1532
  • Product name: pamam dendrimer, generation 4.5 solution
  • CAS: 202009-66-3
  • MF: C16H1632N25Na128O38
  • MW: 0
  • EINECS:
  • MDL Number:MFCD00804247
  • Synonyms:PAMAM dendrimer, ethylenediamine core, generation 4.5 solution;PAMAM dendrimer, ethylenediamine core, generation 4.5 solution 5 wt. % in methanol
7 prices
Selected condition:
Brand
  • aablocks
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • Sigma-Aldrich
Package
  • 5MG
  • 500mg
  • 1g
  • 2.5g
  • 10g
  • Manufactureraablocks
  • Product numberAA00BJCO
  • Product descriptionpamam dendrimer, generation 4.5 solution
  • Packaging2.5g
  • Price$437
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00BJCO
  • Product descriptionpamam dendrimer, generation 4.5 solution
  • Packaging10g
  • Price$1532
  • Updated2026-05-28
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberPOL0002876
  • Product descriptionPAMAM DENDRIMER, ETHYLENEDIAMINE CORE, GENERATION 4.5 95.00%
  • Packaging5MG
  • Price$503.03
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number39109
  • Product descriptionPAMAM Dendrimer G4.5 Carboxylate (sodium salt) (water solution)
  • Packaging1g
  • Price$667
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number39109
  • Product descriptionPAMAM Dendrimer G4.5 Carboxylate (sodium salt) (water solution)
  • Packaging500mg
  • Price$351
  • Updated2026-04-30
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number470457
  • Product descriptionPAMAM dendrimer, ethylenediamine core, generation 4.5 solution 5 wt. % in methanol
  • Packaging2.5g
  • Price$374
  • Updated2026-04-30
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number470457
  • Product descriptionPAMAM dendrimer, ethylenediamine core, generation 4.5 solution 5 wt. % in methanol
  • Packaging10g
  • Price$1120
  • Updated2026-04-30
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00BJCO pamam dendrimer, generation 4.5 solution 2.5g $437 2026-05-28 Buy
aablocks AA00BJCO pamam dendrimer, generation 4.5 solution 10g $1532 2026-05-28 Buy
American Custom Chemicals Corporation POL0002876 PAMAM DENDRIMER, ETHYLENEDIAMINE CORE, GENERATION 4.5 95.00% 5MG $503.03 2021-12-16 Buy
Cayman Chemical 39109 PAMAM Dendrimer G4.5 Carboxylate (sodium salt) (water solution) 1g $667 2026-04-30 Buy
Cayman Chemical 39109 PAMAM Dendrimer G4.5 Carboxylate (sodium salt) (water solution) 500mg $351 2026-04-30 Buy
Sigma-Aldrich 470457 PAMAM dendrimer, ethylenediamine core, generation 4.5 solution 5 wt. % in methanol 2.5g $374 2026-04-30 Buy
Sigma-Aldrich 470457 PAMAM dendrimer, ethylenediamine core, generation 4.5 solution 5 wt. % in methanol 10g $1120 2026-04-30 Buy

Properties

Boiling point :65 °C
Density :0.791 g/mL at 25 °C
refractive index :n20/D 1.337
Flash point :11 °C
solubility :Water: soluble
form :5 wt.% in methanol
InChI :1S/C14H24N2O8.4Na/c17-11(18)1-5-15(6-2-12(19)20)9-10-16(7-3-13(21)22)8-4-14(23)24;;;;/h1-10H2,(H,17,18)(H,19,20)(H,21,22)(H,23,24);;;;/q;4*+1/p-4
InChIKey :CJVPOGPEEJPBFT-UHFFFAOYSA-J
SMILES :[Na+].[Na+].[Na+].[Na+].N(CCN(CCC(=O)[O-])CCC(=O)[O-])(CCC(=O)[O-])CCC(=O)[O-]

Safety Information

Symbol(GHS): Flame (GHS02)Skull and Crossbones (GHS06)Health Hazard (GHS08)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger P260, P264, P270, P307+P311, P321,P405, P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

PAMAM dendrimer G4.5 carboxylate (PAMAM G4.5 carboxylate) is a polyamidoamine (PAMAM) dendrimer with carboxylate termini that has been used as a drug delivery system.1 It is approximately 87.9 Å in diameter in water and has 96 surface groups.2 Unlike the amine-terminated PAMAM G5.0 (Item No. 39075), it does not rupture bilayer lipid membranes when used at a concentration of 50 µM.3 PAMAM G4.5 carboxylate disulfur-linked aggregates (10 µg/ml) encapsulating the phenol ferulic acid (Item No. 19871) and the mitotic inhibitor paclitaxel (Item No. 10461) induce apoptosis and decrease the mitochondrial membrane potential in multidrug-resistant KB-8-5 epidermal carcinoma cells.1 Complexes of PAMAM G4.5 carboxylate with the active component of cisplatin are cytotoxic to A2780 ovarian cancer cells (IC50 = 620 nM).4 A fluorescently labeled form of PAMAM G4.5 carboxylate selectively accumulates in tumors and kidneys over liver, spleen, heart, and lungs in a 4T1 murine mammary carcinoma model.5WARNING This product is not for human or veterinary use.

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