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ChemicalBook >> CAS DataBase List >> N-(5-ADAMANTANE-1-YL-METHOXY)-PENTYL-DEOXYNOJIRIMYCIN

N-(5-ADAMANTANE-1-YL-METHOXY)-PENTYL-DEOXYNOJIRIMYCIN

N-(5-ADAMANTANE-1-YL-METHOXY)-PENTYL-DEOXYNOJIRIMYCIN price.
  • $43 - $2418
  • Product name: N-(5-ADAMANTANE-1-YL-METHOXY)-PENTYL-DEOXYNOJIRIMYCIN
  • CAS: 216758-20-2
  • MF: C22H39NO5
  • MW: 397.55
  • EINECS:
  • MDL Number:MFCD01863330
  • Synonyms:N-(5-ADAMANTANE-1-YL-METHOXY)-PENTYL-DEOXYNOJIRIMYCIN;2R-(HYDROXYMETHYL)-1-[5-(TRICYCLO[3.3.2.13,7]DEC-1-YLMETHOXY)PENTYL]-3R,4R,5S-PIPERIDINETRIOL;ADAMANTANE-PENTYL-DNM;AMP-DEOXYNOJIRIMYCIN;N-(5-AdaMant-1-yl-Methoxy)pentyl DeoxynojiriMycin;AMP-Deoxynojirimycin - Solution in ethanol;AMP-Deoxynojirimycin Exclusive;3,4,5-Piperidinetriol, 2-(hydroxymethyl)-1-[5-(tricyclo[3.3.1.13,7]dec-1-ylmethoxy)pentyl]-, (2R,3R,4R,5S)-
56 prices
Selected condition:
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • American Custom Chemicals Corporation
  • Arctom
  • Biosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Usbiological
Package
  • 10mM*1mLinDMSO(Solution)
  • 500μg
  • 2mg
  • 50mg
  • 250mg
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 1mg
  • 5mg
  • 10MG
  • 25MG
  • 100MG
  • Manufactureraablocks
  • Product numberAA007PDX
  • Product descriptionAMP-Deoxynojirimycin ≥95%
  • Packaging1mg
  • Price$90
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA007PDX
  • Product descriptionAMP-Deoxynojirimycin ≥95%
  • Packaging5mg
  • Price$366
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberAD251470
  • Product descriptionAMP-Deoxynojirimycin 98%
  • Packaging5MG
  • Price$495
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberAD251470
  • Product descriptionAMP-Deoxynojirimycin 98%
  • Packaging10MG
  • Price$705
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberAD251470
  • Product descriptionAMP-Deoxynojirimycin 98%
  • Packaging25MG
  • Price$1125
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberAD251470
  • Product descriptionAMP-Deoxynojirimycin 98%
  • Packaging100MG
  • Price$2015
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number1613AH
  • Product descriptionAMP-Deoxynojirimycin
  • Packaging5mg
  • Price$467
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCCH0005905
  • Product description2R-(HYDROXYMETHYL)-1-(5-(TRICYCLO(3.3.2.13,7)DEC-1-YLMETHOXY)PENTYL)-3R,4R,5S-PIPERIDINETRIOL 95.00%
  • Packaging5MG
  • Price$499.24
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberHY-114615
  • Product descriptionAMP-Deoxynojirimycin 98.0%
  • Packaging5mg
  • Price$559
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-114615
  • Product descriptionAMP-Deoxynojirimycin 98.0%
  • Packaging10mg
  • Price$793
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-114615
  • Product descriptionAMP-Deoxynojirimycin 98.0%
  • Packaging10mM*1mLinDMSO(Solid+Solvent)
  • Price$615
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-114615
  • Product descriptionAMP-Deoxynojirimycin 98.0%
  • Packaging10mM*1mLinDMSO(Solution)
  • Price$615
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-114615
  • Product descriptionAMP-Deoxynojirimycin 98.0%
  • Packaging1mg
  • Price$173
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-114615
  • Product descriptionAMP-Deoxynojirimycin 98.0%
  • Packaging50mg
  • Price$1754
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-114615
  • Product descriptionAMP-Deoxynojirimycin 98.0%
  • Packaging25mg
  • Price$1349
  • Updated2026-05-26
  • Buy
  • ManufacturerBiosynth
  • Product numberMA31098
  • Product descriptionAMP-Deoxynojirimycin - Solution in ethanol
  • Packaging10mg
  • Price$1150
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA007PDX AMP-Deoxynojirimycin ≥95% 1mg $90 2026-05-28 Buy
aablocks AA007PDX AMP-Deoxynojirimycin ≥95% 5mg $366 2026-05-28 Buy
ACHEMBLOCK AD251470 AMP-Deoxynojirimycin 98% 5MG $495 2026-05-27 Buy
ACHEMBLOCK AD251470 AMP-Deoxynojirimycin 98% 10MG $705 2026-05-27 Buy
ACHEMBLOCK AD251470 AMP-Deoxynojirimycin 98% 25MG $1125 2026-05-27 Buy
ACHEMBLOCK AD251470 AMP-Deoxynojirimycin 98% 100MG $2015 2026-05-27 Buy
AK Scientific 1613AH AMP-Deoxynojirimycin 5mg $467 2021-12-16 Buy
American Custom Chemicals Corporation CCH0005905 2R-(HYDROXYMETHYL)-1-(5-(TRICYCLO(3.3.2.13,7)DEC-1-YLMETHOXY)PENTYL)-3R,4R,5S-PIPERIDINETRIOL 95.00% 5MG $499.24 2021-12-16 Buy
Arctom HY-114615 AMP-Deoxynojirimycin 98.0% 5mg $559 2026-05-26 Buy
Arctom HY-114615 AMP-Deoxynojirimycin 98.0% 10mg $793 2026-05-26 Buy
Arctom HY-114615 AMP-Deoxynojirimycin 98.0% 10mM*1mLinDMSO(Solid+Solvent) $615 2026-05-26 Buy
Arctom HY-114615 AMP-Deoxynojirimycin 98.0% 10mM*1mLinDMSO(Solution) $615 2026-05-26 Buy
Arctom HY-114615 AMP-Deoxynojirimycin 98.0% 1mg $173 2026-05-26 Buy
Arctom HY-114615 AMP-Deoxynojirimycin 98.0% 50mg $1754 2026-05-26 Buy
Arctom HY-114615 AMP-Deoxynojirimycin 98.0% 25mg $1349 2026-05-26 Buy
Biosynth MA31098 AMP-Deoxynojirimycin - Solution in ethanol 10mg $1150 2021-12-16 Buy

Properties

Boiling point :569.9±50.0 °C(Predicted)
Density :1.214±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
pka :13.72±0.70(Predicted)
form :powder
color :white to beige
InChI :1S/C22H39NO5/c24-13-18-20(26)21(27)19(25)12-23(18)4-2-1-3-5-28-14-22-9-15-6-16(10-22)8-17(7-15)11-22/h15-21,24-27H,1-14H2/t15-,16+,17-,18-,19+,20-,21-,22/m1/s1
InChIKey :XVYLNHVEAOOEGI-OIPNBASOSA-N
SMILES :O[C@@H]1[C@H](N(C[C@@H]([C@H]1O)O)CCCCCOCC2(C3)C[C@@H](C4)C[C@H]3C[C@@H]4C2)CO

Safety Information

Symbol(GHS): Flame (GHS02)Exclamation Mark (GHS07)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 Keep container tightly closed.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P403+P235 Store in a well-ventilated place. Keep cool.
P501 Dispose of contents/container to..…

Description

AMP-Deoxynojirimycin (AMP-dNM) is a hydrophobic derivative of dNM that potently inhibits β-glucosidase 2 (BGD, IC50 = 0.3 nM), less potently antagonizes glucosylceramide synthase (GCS, IC50 = 25 nM), and only poorly inhibits other GCase isoforms. The lipid messenger ceramide is converted to glucosylceramide by GCS. In the reverse direction, BGD cleaves the glucosyl moiety from glucosylceramide, liberating ceramide, which can be converted into sphingomyelin. AMP-dNM has been shown to induce sterol regulatory element-binding protein-regulated gene expression and cholesterol synthesis in Hep-G2 cells, strongly suppress inflammation in a murine model of hapten-induced colitis, and enhance insulin sensitivity in murine and rat models of insulin resistance.

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