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ChemicalBook >> CAS DataBase List >> α,α-Diphenyl-4-[(3-pyridinylmethylene)amino]-1-piperazinepentanenitrile

α,α-Diphenyl-4-[(3-pyridinylmethylene)amino]-1-piperazinepentanenitrile

$32 - $2839
Product name: α,α-Diphenyl-4-[(3-pyridinylmethylene)amino]-1-piperazinepentanenitrile
CAS: 218136-59-5
MF: C27H29N5
MW: 423.55
EINECS:
MDL Number:MFCD11226148
Synonyms:SC 26196;α,α-Diphenyl-4-[(3-pyridinylmethylene)amino]-1-piperazinepentanenitrile;alpha,alpha-Diphenyl-4-[(3-pyridinylmethylene)amino]-1-piperazinepentanenitrile;α,α-Diphenyl-4-[(3-pyridinylMethylene)aMino]-1-piperazine;2,2-diphenyl-5-{4-[(E)-(pyridin-3-ylMethylidene)aMino]piperazin-1-yl}pentanenitrile;PF-o6341724;(E)-2,2-diphenyl-5-(4-((pyridin-3-ylMethylene)aMino)piperazin-1-yl)pentanenitrile;2,2-diphenyl-5-(4-[[(1 E)-pyridin-3-yl-methylidene]amino]piperazin-1-yl)pentanenitrile

Price50 Properties Safety Information Description

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Brand

aablocks
ACHEMBLOCK
American Custom Chemicals Corporation
ApexBio Technology
Axon Medchem
Biorbyt Ltd
Cayman Chemical
Chemenu
CSNpharm
DC Chemicals
Matrix Scientific
Medical Isotopes, Inc.
Sigma-Aldrich
Tocris
TRC
Usbiological

Package

10
1mg
50
5mg
10mg
25mg
50mg
100.00mg
100MG
250.00mg
250mg
1000mg
10mM*1mLinDMSO
1.00g
1g

Manufactureraablocks
Product numberAA00C2O4
Product description2,2-Diphenyl-5-(4-((Pyridin-3-Ylmethylene)Amino)Piperazin-1-Yl)Pentanenitrile ≥98%
Packaging1mg
Price$36
Updated2026-05-28
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Manufactureraablocks
Product numberAA00C2O4
Product description2,2-Diphenyl-5-(4-((Pyridin-3-Ylmethylene)Amino)Piperazin-1-Yl)Pentanenitrile ≥98%
Packaging5mg
Price$40
Updated2026-05-28
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Manufactureraablocks
Product numberAA00C2O4
Product description2,2-Diphenyl-5-(4-((Pyridin-3-Ylmethylene)Amino)Piperazin-1-Yl)Pentanenitrile ≥98%
Packaging10mg
Price$71
Updated2026-05-28
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Manufactureraablocks
Product numberAA00C2O4
Product description2,2-Diphenyl-5-(4-((Pyridin-3-Ylmethylene)Amino)Piperazin-1-Yl)Pentanenitrile ≥98%
Packaging25mg
Price$155
Updated2026-05-28
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Manufactureraablocks
Product numberAA00C2O4
Product description2,2-Diphenyl-5-(4-((Pyridin-3-Ylmethylene)Amino)Piperazin-1-Yl)Pentanenitrile ≥98%
Packaging50mg
Price$203
Updated2026-05-28
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ManufacturerACHEMBLOCK
Product numberX203397
Product descriptionSC-26196 98.00%
Packaging100MG
Price$365
Updated2026-05-25
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ManufacturerACHEMBLOCK
Product numberX203397
Product descriptionSC-26196 98.00%
Packaging100MG
Price$365
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberX203397
Product descriptionSC-26196 98.00%
Packaging25MG
Price$130
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberX203397
Product descriptionSC-26196 98.00%
Packaging25MG
Price$130
Updated2026-05-25
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ManufacturerAmerican Custom Chemicals Corporation
Product numberAPI0010312
Product descriptionALPHA,ALPHA-DIPHENYL-4-[(3-PYRIDINYLMETHYLENE)AMINO]-1-PIPERAZINEPENTANENITRILE 95.00%
Packaging100MG
Price$1686.3
Updated2021-12-16
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ManufacturerAmerican Custom Chemicals Corporation
Product numberAPI0010312
Product descriptionALPHA,ALPHA-DIPHENYL-4-[(3-PYRIDINYLMETHYLENE)AMINO]-1-PIPERAZINEPENTANENITRILE 95.00%
Packaging10MG
Price$716.1
Updated2021-12-16
Buy

ManufacturerAmerican Custom Chemicals Corporation
Product numberAPI0010312
Product descriptionALPHA,ALPHA-DIPHENYL-4-[(3-PYRIDINYLMETHYLENE)AMINO]-1-PIPERAZINEPENTANENITRILE 95.00%
Packaging5MG
Price$242
Updated2021-12-16
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ManufacturerApexBio Technology
Product numberB7608
Product descriptionSC 26196
Packaging10mg
Price$165
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberB7608
Product descriptionSC26196
Packaging10mg
Price$202
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberB7608
Product descriptionSC26196
Packaging50mg
Price$852
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberB7608
Product descriptionSC 26196
Packaging50mg
Price$471
Updated2026-05-06
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA00C2O4	2,2-Diphenyl-5-(4-((Pyridin-3-Ylmethylene)Amino)Piperazin-1-Yl)Pentanenitrile ≥98%	1mg	$36	2026-05-28	Buy
aablocks	AA00C2O4	2,2-Diphenyl-5-(4-((Pyridin-3-Ylmethylene)Amino)Piperazin-1-Yl)Pentanenitrile ≥98%	5mg	$40	2026-05-28	Buy
aablocks	AA00C2O4	2,2-Diphenyl-5-(4-((Pyridin-3-Ylmethylene)Amino)Piperazin-1-Yl)Pentanenitrile ≥98%	10mg	$71	2026-05-28	Buy
aablocks	AA00C2O4	2,2-Diphenyl-5-(4-((Pyridin-3-Ylmethylene)Amino)Piperazin-1-Yl)Pentanenitrile ≥98%	25mg	$155	2026-05-28	Buy
aablocks	AA00C2O4	2,2-Diphenyl-5-(4-((Pyridin-3-Ylmethylene)Amino)Piperazin-1-Yl)Pentanenitrile ≥98%	50mg	$203	2026-05-28	Buy
ACHEMBLOCK	X203397	SC-26196 98.00%	100MG	$365	2026-05-25	Buy
ACHEMBLOCK	X203397	SC-26196 98.00%	100MG	$365	2026-05-27	Buy
ACHEMBLOCK	X203397	SC-26196 98.00%	25MG	$130	2026-05-27	Buy
ACHEMBLOCK	X203397	SC-26196 98.00%	25MG	$130	2026-05-25	Buy
American Custom Chemicals Corporation	API0010312	ALPHA,ALPHA-DIPHENYL-4-[(3-PYRIDINYLMETHYLENE)AMINO]-1-PIPERAZINEPENTANENITRILE 95.00%	100MG	$1686.3	2021-12-16	Buy
American Custom Chemicals Corporation	API0010312	ALPHA,ALPHA-DIPHENYL-4-[(3-PYRIDINYLMETHYLENE)AMINO]-1-PIPERAZINEPENTANENITRILE 95.00%	10MG	$716.1	2021-12-16	Buy
American Custom Chemicals Corporation	API0010312	ALPHA,ALPHA-DIPHENYL-4-[(3-PYRIDINYLMETHYLENE)AMINO]-1-PIPERAZINEPENTANENITRILE 95.00%	5MG	$242	2021-12-16	Buy
ApexBio Technology	B7608	SC 26196	10mg	$165	2026-05-06	Buy
ApexBio Technology	B7608	SC26196	10mg	$202	2021-12-16	Buy
ApexBio Technology	B7608	SC26196	50mg	$852	2021-12-16	Buy
ApexBio Technology	B7608	SC 26196	50mg	$471	2026-05-06	Buy

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Properties

storage temp. :2-8°C
solubility :DMSO: ≥10mg/mL
form :powder
color :white to tan
InChI :1S/C27H29N5/c28-23-27(25-10-3-1-4-11-25,26-12-5-2-6-13-26)14-8-16-31-17-19-32(20-18-31)30-22-24-9-7-15-29-21-24/h1-7,9-13,15,21-22H,8,14,16-20H2/b30-22+
InChIKey :QFYKXKMYVYOUNJ-JBASAIQMSA-N
SMILES :N#CC(CCCN1CCN(CC1)\N=C\c2cccnc2)(c3ccccc3)c4ccccc4

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312	IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352	IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

SC 26196 is an inhibitor of Δ6 desaturase (IC50 = 0.2 μM in a rat liver microsomal assay) that completely blocks the conversion of linoleic acid to arachidonic acid (AA). It is selective for Δ6 desaturase, as IC50 values for Δ5 and Δ9 desaturases exceed 200 μM and it has no effect on the conversion of dihomo-γ-linolenic acid to AA. SC 26196 is orally active in vivo, decreasing edema in the carrageenan paw edema model in mice. It also blocks aging-related increases in AA in myocardial cardiolipin in mice, attenuating contractile dysfunction without impacting mitochondrial oxidative stress.

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α,α-Diphenyl-4-[(3-pyridinylmethylene)amino]-1-piperazinepentanenitrile

Properties

Safety Information

Description

Related product price

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