25-Hydroxycholesterol
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- $15 - $1880
- Product name: 25-Hydroxycholesterol
- CAS: 2140-46-7
- MF: C27H46O2
- MW: 402.65
- EINECS:218-362-5
- MDL Number:MFCD00057815
- Synonyms:3BETA,25-DIHYDROXY-5-CHOLESTENE;5-CHOLESTEN-3-BETA, 25-DIOL;5-CHOLESTENE-3BETA,25-DIOL;25-Hydroxycholesterol (not deuterated);Cholest-5-ene-3,25-diol, (3.beta.)-;5-cholestene-3β,25-diol;(3S,8S,9S,10R,13R,14S,17R)-17-[(2R)-6-hydroxy-6-methyl-heptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol;3β,25-Dihydroxycholest-5-ene
59 prices
Selected condition:
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- Arctom
- AvaChem
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Synthonix
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 10
- 1mg
- 5mg
- 10.00mg
- 10mg
- 25mg
- 25.00mg
- 50.00mg
- 50mg
- 100.00mg
- 100mg
- 250MG
- 250.00mg
- 1G
- 5G
- Manufactureraablocks
- Product numberAA0037SC
- Product description25-Hydroxycholesterol 95%
- Packaging1mg
- Price$15
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0037SC
- Product description25-Hydroxycholesterol 95%
- Packaging5mg
- Price$30
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0037SC
- Product description25-Hydroxycholesterol 98%
- Packaging10mg
- Price$40
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0037SC
- Product description25-Hydroxycholesterol 98%
- Packaging50mg
- Price$99
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0037SC
- Product description25-Hydroxycholesterol 95%
- Packaging25mg
- Price$71
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0037SC
- Product description25-Hydroxycholesterol 98%
- Packaging100mg
- Price$128
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberX191909
- Product description(3S,8S,9S,10R,13R,14S,17R)-17-[(R)-6-Hydroxy-6-methyl-2-heptyl]-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 97.00%
- Packaging1G
- Price$470
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberX191909
- Product description(3S,8S,9S,10R,13R,14S,17R)-17-[(R)-6-Hydroxy-6-methyl-2-heptyl]-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 97.00%
- Packaging5G
- Price$1880
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberX191909
- Product description(3S,8S,9S,10R,13R,14S,17R)-17-[(R)-6-Hydroxy-6-methyl-2-heptyl]-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 97.00%
- Packaging250MG
- Price$155
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number1865BA
- Product description25-Hydroxycholesterol
- Packaging1g
- Price$1680
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA185451
- Product description(3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 95+%
- Packaging100mg
- Price$175
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA185451
- Product description(3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 95+%
- Packaging250mg
- Price$288
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA185451
- Product description(3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 95+%
- Packaging25mg
- Price$76
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA185451
- Product description(3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 95+%
- Packaging50mg
- Price$112
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA185451
- Product description(3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 95+%
- Packaging10mg
- Price$53
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA185451
- Product description(3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 95+%
- Packaging5mg
- Price$29
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA0037SC | 25-Hydroxycholesterol 95% | 1mg | $15 | 2026-05-28 | Buy |
| aablocks | AA0037SC | 25-Hydroxycholesterol 95% | 5mg | $30 | 2026-05-28 | Buy |
| aablocks | AA0037SC | 25-Hydroxycholesterol 98% | 10mg | $40 | 2026-05-28 | Buy |
| aablocks | AA0037SC | 25-Hydroxycholesterol 98% | 50mg | $99 | 2026-05-28 | Buy |
| aablocks | AA0037SC | 25-Hydroxycholesterol 95% | 25mg | $71 | 2026-05-28 | Buy |
| aablocks | AA0037SC | 25-Hydroxycholesterol 98% | 100mg | $128 | 2026-05-28 | Buy |
| ACHEMBLOCK | X191909 | (3S,8S,9S,10R,13R,14S,17R)-17-[(R)-6-Hydroxy-6-methyl-2-heptyl]-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 97.00% | 1G | $470 | 2026-05-27 | Buy |
| ACHEMBLOCK | X191909 | (3S,8S,9S,10R,13R,14S,17R)-17-[(R)-6-Hydroxy-6-methyl-2-heptyl]-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 97.00% | 5G | $1880 | 2026-05-27 | Buy |
| ACHEMBLOCK | X191909 | (3S,8S,9S,10R,13R,14S,17R)-17-[(R)-6-Hydroxy-6-methyl-2-heptyl]-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 97.00% | 250MG | $155 | 2026-05-27 | Buy |
| AK Scientific | 1865BA | 25-Hydroxycholesterol | 1g | $1680 | 2021-12-16 | Buy |
| Ambeed | A185451 | (3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 95+% | 100mg | $175 | 2021-12-16 | Buy |
| Ambeed | A185451 | (3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 95+% | 250mg | $288 | 2021-12-16 | Buy |
| Ambeed | A185451 | (3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 95+% | 25mg | $76 | 2021-12-16 | Buy |
| Ambeed | A185451 | (3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 95+% | 50mg | $112 | 2021-12-16 | Buy |
| Ambeed | A185451 | (3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 95+% | 10mg | $53 | 2021-12-16 | Buy |
| Ambeed | A185451 | (3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 95+% | 5mg | $29 | 2021-12-16 | Buy |
Properties
Melting point :177-179 °C
Boiling point :513.1±23.0 °C(Predicted)
Density :1.03±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :chloroform: 50 mg/mL, clear, colorless to slightly yellow
form :solid
pka :15.03±0.70(Predicted)
color :White or pale yellow
biological source :synthetic (organic)
Merck :13,4846
BRN :3161259
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChIKey :INBGSXNNRGWLJU-ZHHJOTBYSA-N
SMILES :[C@@]12([H])CC[C@H]([C@H](C)CCCC(O)(C)C)[C@@]1(C)CC[C@]1([H])[C@@]3(C)CC[C@H](O)CC3=CC[C@@]21[H] |&1:0,4,5,14,18,20,24,30,r|
Boiling point :513.1±23.0 °C(Predicted)
Density :1.03±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :chloroform: 50 mg/mL, clear, colorless to slightly yellow
form :solid
pka :15.03±0.70(Predicted)
color :White or pale yellow
biological source :synthetic (organic)
Merck :13,4846
BRN :3161259
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChIKey :INBGSXNNRGWLJU-ZHHJOTBYSA-N
SMILES :[C@@]12([H])CC[C@H]([C@H](C)CCCC(O)(C)C)[C@@]1(C)CC[C@]1([H])[C@@]3(C)CC[C@H](O)CC3=CC[C@@]21[H] |&1:0,4,5,14,18,20,24,30,r|
Safety Information
| Symbol(GHS): |
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| Signal word: | Warning | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Description
25-hydroxy Cholesterol is a side-chain substituted oxysterol derived from dietary cholesterol that inhibits the cleavage of sterol regulatory element binding proteins (SREBPs) to suppress endogenous cholesterol synthesis in various cell types. It has been implicated in a variety of metabolic events including cholesterol homeostasis and atherosclerosis as well as antitumor activities as it has been shown to induce apoptosis through down-regulation of Bcl-2 expression and activation of caspases. Immunomodulating capabilities have also been observed as the oxysterol can act as a LXR-RXR ligand coupling cholesterol synthesis to T cell proliferation, can reduce (EC50 ~ 65 nM) IgA production by B cells in response to IL-2, and can suppress differentiation of monocytes into macrophages.More related product prices
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