27-Hydroxycholesterol
|
- $54 - $759
- Product name: 27-Hydroxycholesterol
- CAS: 20380-11-4
- MF: C27H46O2
- MW: 402.65
- EINECS:200-001-8
- MDL Number:MFCD00272990
- Synonyms:(3S,8S,9S,10R,13R,14S,17R)-17-[(2R)-7-hydroxy-6-methyl-heptan-2-yl]-10,13-d;26-Hydroxycholesterol (not deuterated);26-Hydroxycholesterol-26,26,27,27,27-D5;(25R)-Cholest-5-en-3β,26β-diol;5,25R-Cholesten-3beta,26-diol;cholest-(25R)-5-ene-3,27-diol;25(R)-27-hydroxy Cholesterol;(25R)-cholest-5-ene-3beta,26-diol
27 prices
Selected condition：
Brand
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 1mg
- 2mg
- 5MG
- 10mg
- 25mg
- 50mg
- 5 mg
- 25 mg
- 48Tests
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberLIP0020820
- Product description5,25R-CHOLESTEN-3-BETA,26-DIOL 95.00%
- Packaging5MG
- Price$456.96
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC4104
- Product description25(R)-27-hydroxyCholesterol
- Packaging10mg
- Price$468
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC4104
- Product description25(R)-27-hydroxy Cholesterol
- Packaging10mg
- Price$676
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberCFN90609
- Product description27-Hydroxycholesterol ≥98%
- Packaging10mg
- Price$218
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1296084
- Product description27-Hydroxycholesterol 99.45%
- Packaging5mg
- Price$220
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1296084
- Product description27-Hydroxycholesterol 99.45%
- Packaging10mg
- Price$270
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1296084
- Product description27-Hydroxycholesterol 99.45%
- Packaging1mg
- Price$90
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1296084
- Product description27-Hydroxycholesterol 99.45%
- Packaging50mg
- Price$670
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1296084
- Product description27-Hydroxycholesterol 99.45%
- Packaging25mg
- Price$430
- Updated2026-05-06
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC146890
- Product description5,25r-Cholesten-3beta,26-diol
- Packaging25mg
- Price$376
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC146890
- Product description5,25r-Cholesten-3beta,26-diol
- Packaging50mg
- Price$654
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC146890
- Product description5,25r-Cholesten-3beta,26-diol
- Packaging5mg
- Price$108
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC146890
- Product description5,25r-Cholesten-3beta,26-diol
- Packaging10mg
- Price$188
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC146890
- Product description5,25r-Cholesten-3beta,26-diol
- Packaging2mg
- Price$54
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number14790
- Product description25(R)-27-hydroxy Cholesterol ≥95%
- Packaging1mg
- Price$57
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14790
- Product description25(R)-27-hydroxy Cholesterol ≥95%
- Packaging1mg
- Price$63
- Updated2026-04-30
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | LIP0020820 | 5,25R-CHOLESTEN-3-BETA,26-DIOL 95.00% | 5MG | $456.96 | 2021-12-16 | Buy |
| ApexBio Technology | C4104 | 25(R)-27-hydroxyCholesterol | 10mg | $468 | 2021-12-16 | Buy |
| ApexBio Technology | C4104 | 25(R)-27-hydroxy Cholesterol | 10mg | $676 | 2026-05-06 | Buy |
| Arctom | CFN90609 | 27-Hydroxycholesterol ≥98% | 10mg | $218 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb1296084 | 27-Hydroxycholesterol 99.45% | 5mg | $220 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1296084 | 27-Hydroxycholesterol 99.45% | 10mg | $270 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1296084 | 27-Hydroxycholesterol 99.45% | 1mg | $90 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1296084 | 27-Hydroxycholesterol 99.45% | 50mg | $670 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1296084 | 27-Hydroxycholesterol 99.45% | 25mg | $430 | 2026-05-06 | Buy |
| Biosynth Carbosynth | FC146890 | 5,25r-Cholesten-3beta,26-diol | 25mg | $376 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC146890 | 5,25r-Cholesten-3beta,26-diol | 50mg | $654 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC146890 | 5,25r-Cholesten-3beta,26-diol | 5mg | $108 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC146890 | 5,25r-Cholesten-3beta,26-diol | 10mg | $188 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC146890 | 5,25r-Cholesten-3beta,26-diol | 2mg | $54 | 2021-12-16 | Buy |
| Cayman Chemical | 14790 | 25(R)-27-hydroxy Cholesterol ≥95% | 1mg | $57 | 2024-03-01 | Buy |
| Cayman Chemical | 14790 | 25(R)-27-hydroxy Cholesterol ≥95% | 1mg | $63 | 2026-04-30 | Buy |
Properties
Melting point :172-174 °C(Solv: hexane (110-54-3); ethyl acetate (141-78-6))
Boiling point :517.1±23.0 °C(Predicted)
Density :1.03
storage temp. :-20°
solubility :Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to 10 mg/ml).
form :White solid.
pka :15.03±0.70(Predicted)
color :White
optical activity :[α]/D -25 to -35°, c =0.5 in chloroform-d
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
InChIKey :FYHRJWMENCALJY-LGIODXKMNA-N
SMILES :[C@@]12([H])CC[C@H]([C@H](C)CCC[C@@H](C)CO)[C@@]1(C)CC[C@]1([H])[C@@]3(C)CC[C@H](O)CC3=CC[C@@]21[H] |&1:0,4,5,10,14,18,20,24,30,r|
Boiling point :517.1±23.0 °C(Predicted)
Density :1.03
storage temp. :-20°
solubility :Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to 10 mg/ml).
form :White solid.
pka :15.03±0.70(Predicted)
color :White
optical activity :[α]/D -25 to -35°, c =0.5 in chloroform-d
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
InChIKey :FYHRJWMENCALJY-LGIODXKMNA-N
SMILES :[C@@]12([H])CC[C@H]([C@H](C)CCC[C@@H](C)CO)[C@@]1(C)CC[C@]1([H])[C@@]3(C)CC[C@H](O)CC3=CC[C@@]21[H] |&1:0,4,5,10,14,18,20,24,30,r|
Safety Information
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Description
The liver x receptors (LXRα and LXRβ) are nuclear hormone receptors whose native ligands, oxysterols, induce the expression of genes involved in cholesterol and fatty acid metabolism. 27-hydroxy Cholesterol, a sterol 27-hydroxylase-mediated cholesterol hydroxylation product, activates LXRα and LXRβ in vitro with EC50 values of 85 and 71 nM, respectively, and is a potent suppressor of cholesterol biosynthesis. 25(R)-27-hydroxy Cholesterol is the more predominant-occurring (~80%) stereoisomer of the endogenous oxysterol 27-hydroxy cholesterol.Related product price
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