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ChemicalBook >> CAS DataBase List >> Cholan-24-oic acid, 3,7-dihydroxy-, MonosodiuM salt, (3a,5b,7b)-

Cholan-24-oic acid, 3,7-dihydroxy-, MonosodiuM salt, (3a,5b,7b)-

Cholan-24-oic acid, 3,7-dihydroxy-, MonosodiuM salt, (3a,5b,7b)- price.
  • $79 - $774
  • Product name: Cholan-24-oic acid, 3,7-dihydroxy-, MonosodiuM salt, (3a,5b,7b)-
  • CAS: 2898-95-5
  • MF: C24H39NaO4
  • MW: 414.55383
  • EINECS:
  • MDL Number:
  • Synonyms:Cholan-24-oic acid, 3,7-dihydroxy-, MonosodiuM salt, (3a,5b,7b)-;(3alpha,5beta,7beta)-3,7-Dihydroxycholan-24-oic acid monosodium salt;Sodium ursodesoxycholate;URSODEOXYCHOLIC ACID SODIUM SALT USP/EP/BP;UDCA Na;Ursodeoxycholate sodium;Ursodeoxycholic acid sodium;gastrointestinal diseases,lipid metabolism,Ursodeoxycholate,GPBAR1,Ursodeoxycholic acid sodium,intestinal barrier integrity,NR1H4,Ursodeoxycholic acid,G-protein coupled receptor 19,hepatic,UCDA,inhibit,oral,GPCR19,Inhibitor,G protein-coupled Bile Acid Receptor 1,Endogenous Metabolite,Ursodiol,FXR,secondary bile acid,TGR5
6 prices
Selected condition:
Brand
  • AK Scientific
  • Cayman Chemical
  • TRC
Package
  • 250mg
  • 500mg
  • 1g
  • 5g
  • 25g
  • ManufacturerAK Scientific
  • Product numberJ11394
  • Product descriptionSodiumursodeoxycholatehydrate
  • Packaging5g
  • Price$651
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15121
  • Product descriptionUrsodeoxycholic Acid (sodium salt) ≥98%
  • Packaging250mg
  • Price$79
  • Updated2023-06-20
  • Buy
  • ManufacturerCayman Chemical
  • Product number15121
  • Product descriptionUrsodeoxycholic Acid (sodium salt) ≥98%
  • Packaging500mg
  • Price$126
  • Updated2023-06-20
  • Buy
  • ManufacturerCayman Chemical
  • Product number15121
  • Product descriptionUrsodeoxycholic Acid (sodium salt) ≥98%
  • Packaging1g
  • Price$218
  • Updated2023-06-20
  • Buy
  • ManufacturerCayman Chemical
  • Product number15121
  • Product descriptionUrsodeoxycholic Acid (sodium salt) ≥98%
  • Packaging5g
  • Price$774
  • Updated2023-06-20
  • Buy
  • ManufacturerTRC
  • Product numberS080833
  • Product descriptionSodiumUrsodeoxycholate
  • Packaging25g
  • Price$255
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J11394 Sodiumursodeoxycholatehydrate 5g $651 2021-12-16 Buy
Cayman Chemical 15121 Ursodeoxycholic Acid (sodium salt) ≥98% 250mg $79 2023-06-20 Buy
Cayman Chemical 15121 Ursodeoxycholic Acid (sodium salt) ≥98% 500mg $126 2023-06-20 Buy
Cayman Chemical 15121 Ursodeoxycholic Acid (sodium salt) ≥98% 1g $218 2023-06-20 Buy
Cayman Chemical 15121 Ursodeoxycholic Acid (sodium salt) ≥98% 5g $774 2023-06-20 Buy
TRC S080833 SodiumUrsodeoxycholate 25g $255 2021-12-16 Buy

Properties

storage temp. :Store at -20°C
solubility :DMF: 5 mg/ml; DMSO: 10 mg/ml; Ethanol: 15 mg/ml
form :A crystalline solid
color :White to off-white
InChIKey :WDFRNBJHDMUMBL-LEMNXDLSNA-M
SMILES :[Na+].[C@H]1(O)C[C@]2([H])[C@](C)(CC1)C1C(C3[C@@](CC1)(C)[C@@H]([C@H](C)CCC([O-])=O)CC3)[C@@H](O)C2 |&1:1,4,6,13,17,18,27,r|

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.

Description

Ursodeoxycholic acid (UDCA) is a hydrophilic bile acid best known for its role in cholesterol gallstone dissolution and the treatment of several liver diseases, including primary biliary cirrhosis. It interferes with the transport activity of the sodium taurocholate cotransporting polypeptide with an IC50 value of 3.6 μM. UDCA also inhibits apoptosis in liver cells by preventing formation of reactive oxygen species and the translocation of the pro-apoptotic protein Bax from the cytosol to the mitochondria.

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