3-AP
|
- $12 - $2395.3
- Product name: 3-AP
- CAS: 143621-35-6
- MF: C7H9N5S
- MW: 195.25
- EINECS:
- MDL Number:MFCD00924747
- Synonyms:3-Apct;C078157;Pan 811;Pan811;Pan-811;2-((3-AMinopyridin-2-yl)Methylene)hydrazinecarbothioaMide;NSC 663249;OCX 0191
49 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- TCI Chemical
- TRC
Package
- 10mM(in1mLDMSO)
- 5mg
- 10mg
- 1mg
- 25.00mg
- 10mM*1mLinDMSO
- 25mg
- 50.00mg
- 50mg
- 100.00mg
- 100mg
- 250mg
- 1000mg
- 1g
- Manufactureraablocks
- Product numberAA007YMG
- Product descriptionTRIAPINE 98%
- Packaging25mg
- Price$52
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007YMG
- Product descriptionTRIAPINE 98%
- Packaging50mg
- Price$82
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007YMG
- Product descriptionTRIAPINE 98%
- Packaging100mg
- Price$131
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007YMG
- Product descriptionTRIAPINE 98%
- Packaging250mg
- Price$230
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007YMG
- Product descriptionTRIAPINE 98%
- Packaging10mg
- Price$32
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007YMG
- Product descriptionTRIAPINE 98%
- Packaging5mg
- Price$23
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007YMG
- Product descriptionTRIAPINE 98%
- Packaging1mg
- Price$12
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberY227012
- Product description3-AP 97.00%
- Packaging250MG
- Price$350
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY227012
- Product description3-AP 97.00%
- Packaging100MG
- Price$180
- Updated2026-05-27
- Buy
- ManufacturerApexBio Technology
- Product numberB3209
- Product descriptionTriapine
- Packaging25mg
- Price$166
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberC4564
- Product description3-AP
- Packaging10mg
- Price$137
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC4564
- Product description3-AP
- Packaging5mg
- Price$78
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC4564
- Product description3-AP
- Packaging25mg
- Price$303
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB3209
- Product descriptionTriapine
- Packaging10mg
- Price$68
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB3209
- Product descriptionTriapine
- Packaging10mM(in1mLDMSO)
- Price$55
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberAS528850
- Product descriptionTriapine ≥98%
- Packaging1g
- Price$640
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA007YMG | TRIAPINE 98% | 25mg | $52 | 2026-05-28 | Buy |
| aablocks | AA007YMG | TRIAPINE 98% | 50mg | $82 | 2026-05-28 | Buy |
| aablocks | AA007YMG | TRIAPINE 98% | 100mg | $131 | 2026-05-28 | Buy |
| aablocks | AA007YMG | TRIAPINE 98% | 250mg | $230 | 2026-05-28 | Buy |
| aablocks | AA007YMG | TRIAPINE 98% | 10mg | $32 | 2026-05-28 | Buy |
| aablocks | AA007YMG | TRIAPINE 98% | 5mg | $23 | 2026-05-28 | Buy |
| aablocks | AA007YMG | TRIAPINE 98% | 1mg | $12 | 2026-05-28 | Buy |
| ACHEMBLOCK | Y227012 | 3-AP 97.00% | 250MG | $350 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y227012 | 3-AP 97.00% | 100MG | $180 | 2026-05-27 | Buy |
| ApexBio Technology | B3209 | Triapine | 25mg | $166 | 2026-05-06 | Buy |
| ApexBio Technology | C4564 | 3-AP | 10mg | $137 | 2021-12-16 | Buy |
| ApexBio Technology | C4564 | 3-AP | 5mg | $78 | 2021-12-16 | Buy |
| ApexBio Technology | C4564 | 3-AP | 25mg | $303 | 2021-12-16 | Buy |
| ApexBio Technology | B3209 | Triapine | 10mg | $68 | 2026-05-06 | Buy |
| ApexBio Technology | B3209 | Triapine | 10mM(in1mLDMSO) | $55 | 2026-05-06 | Buy |
| Arctom | AS528850 | Triapine ≥98% | 1g | $640 | 2021-12-16 | Buy |
Properties
Melting point :234 °C
Boiling point :436.0±55.0 °C(Predicted)
Density :1.46±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble10Meq/mL, clear
pka :10.93±0.70(Predicted)
form :powder
color :white to light brown
InChI :1S/C7H9N5S/c8-5-2-1-3-10-6(5)4-11-12-7(9)13/h1-4H,8H2,(H3,9,12,13)/b11-4+
InChIKey :XMYKNCNAZKMVQN-NYYWCZLTSA-N
SMILES :S=C(N\N=C\c1ncccc1N)N
CAS DataBase Reference :143621-35-6
Boiling point :436.0±55.0 °C(Predicted)
Density :1.46±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble10Meq/mL, clear
pka :10.93±0.70(Predicted)
form :powder
color :white to light brown
InChI :1S/C7H9N5S/c8-5-2-1-3-10-6(5)4-11-12-7(9)13/h1-4H,8H2,(H3,9,12,13)/b11-4+
InChIKey :XMYKNCNAZKMVQN-NYYWCZLTSA-N
SMILES :S=C(N\N=C\c1ncccc1N)N
CAS DataBase Reference :143621-35-6
Safety Information
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Description
Ribonucleotide reductase, the rate-limiting enzyme for de novo DNA synthesis, is an excellent target for chemotherapy. Its increased activity in cancer cells is associated with malignant transformation and proliferation. 3-AP is a ribonucleotide reductase inhibitor and iron chelator with antitumor activity. At 5 μM it can enhance DU145, U251, and PSN1 tumor cell radiosensitivity in vitro, inhibiting DNA synthesis and repair. It destroys the tyrosine free radical in the R2/p53R2 subunits of ribonucleotide reductase by forming a redox active complex with iron, thus producing reactive oxygen species. Furthermore, 3-AP has been shown to activate an endoplasmic reticulum stress pathway, leading to the unfolded protein response and apoptosis.More related product prices
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