3-aminophenoxazone
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- $68 - $4766.8
- Product name: 3-aminophenoxazone
- CAS: 1916-59-2
- MF: C12H8N2O2
- MW: 212.2
- EINECS:
- MDL Number:MFCD00207317
- Synonyms:3-aminophenoxazone;2-Amino-3-oxo-3H-phenoxazine;2-Aminophenoxazon;Phx-3;Questiomycin A;2-AMino-3-phenoxazone;3H-Phenoxazin-3-one, 2-aMino-;2-AMino-3H-phenoxazin-3-one, 2-AMinophenoxazone, AV Toxin C, NSC 94945
12 prices
Selected condition：
Brand
- AK Scientific
- Alichem
- Biorbyt Ltd
- Cayman Chemical
- Crysdot
- DC Chemicals
- TRC
Package
- 1mg
- 5mg
- 10mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number2266BA
- Product description2-Amino-3H-phenoxazin-3-one
- Packaging1mg
- Price$174
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number1916592
- Product description2-Amino-3H-phenoxazin-3-one
- Packaging1g
- Price$498.2
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb611991
- Product descriptionQuestiomycin A >98%
- Packaging100mg
- Price$1431.4
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb611991
- Product descriptionQuestiomycin A >98%
- Packaging250mg
- Price$2395.3
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb611991
- Product descriptionQuestiomycin A >98%
- Packaging1g
- Price$4766.8
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number27623
- Product descriptionQuestiomycin A
- Packaging1mg
- Price$68
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number27623
- Product descriptionQuestiomycin A
- Packaging5mg
- Price$319
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number27623
- Product descriptionQuestiomycin A
- Packaging10mg
- Price$570
- Updated2024-03-01
- Buy
- ManufacturerCrysdot
- Product numberCD11175962
- Product description2-Amino-3H-phenoxazin-3-one 97%
- Packaging1g
- Price$470
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC26061
- Product descriptionQuestiomycinA >98%
- Packaging250mg
- Price$1600
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC26061
- Product descriptionQuestiomycinA >98%
- Packaging1g
- Price$3200
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberQ509800
- Product descriptionQuestiomycinA
- Packaging10mg
- Price$500
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2266BA | 2-Amino-3H-phenoxazin-3-one | 1mg | $174 | 2021-12-16 | Buy |
| Alichem | 1916592 | 2-Amino-3H-phenoxazin-3-one | 1g | $498.2 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611991 | Questiomycin A >98% | 100mg | $1431.4 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611991 | Questiomycin A >98% | 250mg | $2395.3 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611991 | Questiomycin A >98% | 1g | $4766.8 | 2021-12-16 | Buy |
| Cayman Chemical | 27623 | Questiomycin A | 1mg | $68 | 2024-03-01 | Buy |
| Cayman Chemical | 27623 | Questiomycin A | 5mg | $319 | 2024-03-01 | Buy |
| Cayman Chemical | 27623 | Questiomycin A | 10mg | $570 | 2024-03-01 | Buy |
| Crysdot | CD11175962 | 2-Amino-3H-phenoxazin-3-one 97% | 1g | $470 | 2021-12-16 | Buy |
| DC Chemicals | DC26061 | QuestiomycinA >98% | 250mg | $1600 | 2021-12-16 | Buy |
| DC Chemicals | DC26061 | QuestiomycinA >98% | 1g | $3200 | 2021-12-16 | Buy |
| TRC | Q509800 | QuestiomycinA | 10mg | $500 | 2021-12-16 | Buy |
Properties
Melting point :249-250 °C
Boiling point :352.04°C (rough estimate)
Density :1.2399 (rough estimate)
refractive index :1.6000 (estimate)
storage temp. :Store at -20°C
solubility :DMF: 2mg/mL; DMSO: 3mg/mL; DMSO:PBS (pH 7.2) (1:20): 0.04mg/mL
form :A solid
pka :2.73±0.20(Predicted)
color :Brown to black
Boiling point :352.04°C (rough estimate)
Density :1.2399 (rough estimate)
refractive index :1.6000 (estimate)
storage temp. :Store at -20°C
solubility :DMF: 2mg/mL; DMSO: 3mg/mL; DMSO:PBS (pH 7.2) (1:20): 0.04mg/mL
form :A solid
pka :2.73±0.20(Predicted)
color :Brown to black
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
Questiomycin A is a phenoxazine and a chromophore that has been found in Streptomyces and has antibacterial and anticancer activities. It is active against M. scrofulaceum, M. marinum, and M. intracellulare (MICs = 2.8, 11.3, and 5.6 μg/ml, respectively) but not M. tuberculosis, M. smegmatis, M. kansasii, or M. fortuitum (MICs = >45 μg/ml). It is also inactive against E. coli, P. aeruginosa, S. tymphimurium, S. aureus, or L. monocytogenes. It is cytotoxic to a variety of cancer cells, including MCF-7, A549, MIA PaCa-2, and LoVo-1 cells (IC50s = 1.67, 5.48, 7.16, and 20.03 μM, respectively) as well as human umbilical vein endothelial cells (HUVECs) but not human embryonic lung fibroblast cells (HELs; IC50s = 16.06 and >50 μM, respectively). Questiomycin A reduces the increased intracellular pH in a variety of cancer cell lines, as well as in HUVECs and HELs. It prevents lung metastasis in a B16 mouse melanoma model of metastasis when administered at a dose of 0.5 mg/kg simultaneously with B16 cells or every three days. It is also a chromophore product of the reducing agent 2-aminophenol oxidation (as 2-amino-phenoxazine-3-one) and has been used as a readout in the study of catalytic oxidation of 2-aminophenol by various metal-containing complexes. It has an absorbance of 435 nm in methanol.Suppliers and manufacturers
BOC Sciences
Career Henan Chemica Co
TargetMol Chemicals Inc.
Aladdin Scientific
Shanghai Boyners Pharm-Tech Co., Ltd.
Hangzhou Sage Chemical Co., Ltd.
Chizhou Kailong Import and Export Trade Co., Ltd.
Shanghai EFE Biological Technology Co., Ltd.
Shanghai YuanYe Biotechnology Co., Ltd.
