3-aminophenoxazone
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- $68 - $4766.8
- Product name: 3-aminophenoxazone
- CAS: 1916-59-2
- MF: C12H8N2O2
- MW: 212.2
- EINECS:
- MDL Number:MFCD00207317
- Synonyms:3-aminophenoxazone;2-Amino-3-oxo-3H-phenoxazine;2-Aminophenoxazon;Phx-3;Questiomycin A;2-AMino-3-phenoxazone;3H-Phenoxazin-3-one, 2-aMino-;2-AMino-3H-phenoxazin-3-one, 2-AMinophenoxazone, AV Toxin C, NSC 94945
15 prices
Selected condition：
Brand
- AK Scientific
- Alichem
- Biorbyt Ltd
- Cayman Chemical
- Crysdot
- DC Chemicals
- TRC
Package
- 1mg
- 5mg
- 10mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number2266BA
- Product description2-Amino-3H-phenoxazin-3-one
- Packaging1mg
- Price$174
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number1916592
- Product description2-Amino-3H-phenoxazin-3-one
- Packaging1g
- Price$498.2
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb611991
- Product descriptionQuestiomycin A >98%
- Packaging100mg
- Price$1431.4
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb611991
- Product descriptionQuestiomycin A >98%
- Packaging250mg
- Price$2395.3
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb611991
- Product descriptionQuestiomycin A >98%
- Packaging1g
- Price$4766.8
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number27623
- Product descriptionQuestiomycin A
- Packaging10mg
- Price$570
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number27623
- Product descriptionQuestiomycin A ≥98%
- Packaging10mg
- Price$627
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number27623
- Product descriptionQuestiomycin A
- Packaging1mg
- Price$68
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number27623
- Product descriptionQuestiomycin A ≥98%
- Packaging1mg
- Price$75
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number27623
- Product descriptionQuestiomycin A
- Packaging5mg
- Price$319
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number27623
- Product descriptionQuestiomycin A ≥98%
- Packaging5mg
- Price$351
- Updated2026-04-30
- Buy
- ManufacturerCrysdot
- Product numberCD11175962
- Product description2-Amino-3H-phenoxazin-3-one 97%
- Packaging1g
- Price$470
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC26061
- Product descriptionQuestiomycinA >98%
- Packaging250mg
- Price$1600
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC26061
- Product descriptionQuestiomycinA >98%
- Packaging1g
- Price$3200
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberQ509800
- Product descriptionQuestiomycinA
- Packaging10mg
- Price$500
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2266BA | 2-Amino-3H-phenoxazin-3-one | 1mg | $174 | 2021-12-16 | Buy |
| Alichem | 1916592 | 2-Amino-3H-phenoxazin-3-one | 1g | $498.2 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611991 | Questiomycin A >98% | 100mg | $1431.4 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611991 | Questiomycin A >98% | 250mg | $2395.3 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611991 | Questiomycin A >98% | 1g | $4766.8 | 2021-12-16 | Buy |
| Cayman Chemical | 27623 | Questiomycin A | 10mg | $570 | 2024-03-01 | Buy |
| Cayman Chemical | 27623 | Questiomycin A ≥98% | 10mg | $627 | 2026-04-30 | Buy |
| Cayman Chemical | 27623 | Questiomycin A | 1mg | $68 | 2024-03-01 | Buy |
| Cayman Chemical | 27623 | Questiomycin A ≥98% | 1mg | $75 | 2026-04-30 | Buy |
| Cayman Chemical | 27623 | Questiomycin A | 5mg | $319 | 2024-03-01 | Buy |
| Cayman Chemical | 27623 | Questiomycin A ≥98% | 5mg | $351 | 2026-04-30 | Buy |
| Crysdot | CD11175962 | 2-Amino-3H-phenoxazin-3-one 97% | 1g | $470 | 2021-12-16 | Buy |
| DC Chemicals | DC26061 | QuestiomycinA >98% | 250mg | $1600 | 2021-12-16 | Buy |
| DC Chemicals | DC26061 | QuestiomycinA >98% | 1g | $3200 | 2021-12-16 | Buy |
| TRC | Q509800 | QuestiomycinA | 10mg | $500 | 2021-12-16 | Buy |
Properties
Melting point :249-250 °C
Boiling point :352.04°C (rough estimate)
Density :1.2399 (rough estimate)
refractive index :1.6000 (estimate)
storage temp. :Store at -20°C
solubility :DMF: 2mg/mL; DMSO: 3mg/mL; DMSO:PBS (pH 7.2) (1:20): 0.04mg/mL
form :A solid
pka :2.73±0.20(Predicted)
color :Brown to black
InChI :InChI=1S/C12H8N2O2/c13-7-5-9-12(6-10(7)15)16-11-4-2-1-3-8(11)14-9/h1-6H,13H2
InChIKey :RDJXPXHQENRCNG-UHFFFAOYSA-N
SMILES :C1C2C(OC3=C(N=2)C=CC=C3)=CC(=O)C=1N
Boiling point :352.04°C (rough estimate)
Density :1.2399 (rough estimate)
refractive index :1.6000 (estimate)
storage temp. :Store at -20°C
solubility :DMF: 2mg/mL; DMSO: 3mg/mL; DMSO:PBS (pH 7.2) (1:20): 0.04mg/mL
form :A solid
pka :2.73±0.20(Predicted)
color :Brown to black
InChI :InChI=1S/C12H8N2O2/c13-7-5-9-12(6-10(7)15)16-11-4-2-1-3-8(11)14-9/h1-6H,13H2
InChIKey :RDJXPXHQENRCNG-UHFFFAOYSA-N
SMILES :C1C2C(OC3=C(N=2)C=CC=C3)=CC(=O)C=1N
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
Questiomycin A is a phenoxazine and a chromophore that has been found in Streptomyces and has antibacterial and anticancer activities. It is active against M. scrofulaceum, M. marinum, and M. intracellulare (MICs = 2.8, 11.3, and 5.6 μg/ml, respectively) but not M. tuberculosis, M. smegmatis, M. kansasii, or M. fortuitum (MICs = >45 μg/ml). It is also inactive against E. coli, P. aeruginosa, S. tymphimurium, S. aureus, or L. monocytogenes. It is cytotoxic to a variety of cancer cells, including MCF-7, A549, MIA PaCa-2, and LoVo-1 cells (IC50s = 1.67, 5.48, 7.16, and 20.03 μM, respectively) as well as human umbilical vein endothelial cells (HUVECs) but not human embryonic lung fibroblast cells (HELs; IC50s = 16.06 and >50 μM, respectively). Questiomycin A reduces the increased intracellular pH in a variety of cancer cell lines, as well as in HUVECs and HELs. It prevents lung metastasis in a B16 mouse melanoma model of metastasis when administered at a dose of 0.5 mg/kg simultaneously with B16 cells or every three days. It is also a chromophore product of the reducing agent 2-aminophenol oxidation (as 2-amino-phenoxazine-3-one) and has been used as a readout in the study of catalytic oxidation of 2-aminophenol by various metal-containing complexes. It has an absorbance of 435 nm in methanol.Suppliers and manufacturers
BOC Sciences
Career Henan Chemica Co
TargetMol Chemicals Inc.
Aladdin Scientific
Shanghai Hanhong Scientific Co., Ltd.
Shanghai Boyners Pharm-Tech Co., Ltd.
Hangzhou Sage Chemical Co., Ltd.
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Chizhou Kailong Import and Export Trade Co., Ltd.
