3-(2,4-Dichloro-5-methoxyphenyl)-2,3-dihydro-2-thioxo-4(1H)-quinazolinone
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- $49 - $1200
- Product name: 3-(2,4-Dichloro-5-methoxyphenyl)-2,3-dihydro-2-thioxo-4(1H)-quinazolinone
- CAS: 338967-87-6
- MF: C15H10Cl2N2O2S
- MW: 353.22
- EINECS:
- MDL Number:MFCD00974506
- Synonyms:3-(2,4-Dichloro-5-methoxyphenyl)-2,3-dihydro-2-thioxo-4(1H)-quinazolinone;Mdivi1/Mdivi-1;Mitochondrial division inhibitor 1;3-(2,4-DICHLORO-5-METHOXYPHENYL)-2-THIOXO-2,3-DIHYDROQUINAZOLIN-4(1H)-ONE EXACT;Mitochondrial Division Inhibitor, mdivi-1 ;3-(2,4-Dichloro-5-methoxyphenyl)-2,3-dihydro-2-thioxo-4(1H)-quinazolinone Mdivi-1;Mitochondrial division inhibitor 1 3-(2,4-Dichloro-5-methoxyphenyl)-2,3-dihydro-2-thioxo-4(1H)-quinazolinone;Mdivi-1, 338967-87-6
29 prices
Selected condition：
Brand
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- Chem-Impex
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 20mg
- 10
- 50
- 5MG
- 10MG
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000199
- Product descriptionMDIVI-1 95.00%
- Packaging5MG
- Price$160.6
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000199
- Product descriptionMDIVI-1 95.00%
- Packaging10MG
- Price$624.57
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4472
- Product descriptionMdivi1
- Packaging50mg
- Price$200
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60325
- Product descriptionMdivi-1 ≥98%
- Packaging20mg
- Price$208
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD65075
- Product descriptionMdivi-1
- Packaging10mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD65075
- Product descriptionMdivi-1
- Packaging50mg
- Price$263
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number15559
- Product descriptionMdivi 1 ≥98%
- Packaging5mg
- Price$49
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15559
- Product descriptionMdivi 1 ≥98%
- Packaging10mg
- Price$92
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15559
- Product descriptionMdivi 1 ≥98%
- Packaging25mg
- Price$190
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15559
- Product descriptionMdivi 1 ≥98%
- Packaging50mg
- Price$356
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM142775
- Product description3-(2,4-dichloro-5-methoxyphenyl)-2-mercaptoquinazolin-4(3H)-one 98%
- Packaging100mg
- Price$281
- Updated2021-12-16
- Buy
- ManufacturerChem-Impex
- Product number42201
- Product descriptionMdivi-1,≥98%(HPLC) ≥98%(HPLC)
- Packaging50MG
- Price$421.66
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-2462
- Product descriptionMdivi-1 99.73%
- Packaging5mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-2462
- Product descriptionMdivi-1 99.73%
- Packaging10mg
- Price$65
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-2462
- Product descriptionMdivi-1 99.73%
- Packaging50mg
- Price$190
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-2462
- Product descriptionMdivi-1 99.73%
- Packaging100mg
- Price$290
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | INB0000199 | MDIVI-1 95.00% | 5MG | $160.6 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000199 | MDIVI-1 95.00% | 10MG | $624.57 | 2021-12-16 | Buy |
| ApexBio Technology | A4472 | Mdivi1 | 50mg | $200 | 2021-12-16 | Buy |
| Arctom | CFN60325 | Mdivi-1 ≥98% | 20mg | $208 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD65075 | Mdivi-1 | 10mg | $75 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD65075 | Mdivi-1 | 50mg | $263 | 2021-12-16 | Buy |
| Cayman Chemical | 15559 | Mdivi 1 ≥98% | 5mg | $49 | 2024-03-01 | Buy |
| Cayman Chemical | 15559 | Mdivi 1 ≥98% | 10mg | $92 | 2024-03-01 | Buy |
| Cayman Chemical | 15559 | Mdivi 1 ≥98% | 25mg | $190 | 2024-03-01 | Buy |
| Cayman Chemical | 15559 | Mdivi 1 ≥98% | 50mg | $356 | 2024-03-01 | Buy |
| Chemenu | CM142775 | 3-(2,4-dichloro-5-methoxyphenyl)-2-mercaptoquinazolin-4(3H)-one 98% | 100mg | $281 | 2021-12-16 | Buy |
| Chem-Impex | 42201 | Mdivi-1,≥98%(HPLC) ≥98%(HPLC) | 50MG | $421.66 | 2021-12-16 | Buy |
| ChemScene | CS-2462 | Mdivi-1 99.73% | 5mg | $50 | 2021-12-16 | Buy |
| ChemScene | CS-2462 | Mdivi-1 99.73% | 10mg | $65 | 2021-12-16 | Buy |
| ChemScene | CS-2462 | Mdivi-1 99.73% | 50mg | $190 | 2021-12-16 | Buy |
| ChemScene | CS-2462 | Mdivi-1 99.73% | 100mg | $290 | 2021-12-16 | Buy |
Properties
Melting point :289 °C
Boiling point :522.5±60.0 °C(Predicted)
Density :1.57±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: >20mg/mL
form :White solid
pka :9.91±0.20(Predicted)
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Boiling point :522.5±60.0 °C(Predicted)
Density :1.57±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: >20mg/mL
form :White solid
pka :9.91±0.20(Predicted)
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety Information
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Description
Mitochondrial fusion and division proteins function via self assembly to regulate membrane dynamics during various cellular events. For example, the self assembly of dynamin-1, a mitochondrial protein that facilitates endocytosis, with a dynamin related-GTPase (Dnm1 (yeast)/Drp1(mammals)), a mitochondrial protein that functions during mitochondrial division, is thought to regulate apoptosis. Mdivi 1 is a quinazolinone derivative that selectively inhibits mitochondrial division by blocking dynamin GTPase activity in yeast (IC50 = 1-10 μM) and mammalian cells (IC50 = ~50 μM). It has been shown to prevent apoptosis by inhibiting mitochondrial outer membrane permeabilization in vivo and to block Bid-activated Bax/Bak-dependent cytochrome c release from mitochondria in vitro. It has been used to maintain mitochondrial integrity and to prevent cell death in models of pathological conditions including cancer, heart failure, and ischemia and reperfusion injuries.Related product price
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Suppliers and manufacturers
Henan Fengda Chemical Co., Ltd
$2.00 /1000kg
3-(2,4-Dichloro-5-methoxyphenyl)-2,3-dihydro-2-thioxo-4(1H)-quinazolinone CAS:338967-87-6
3-(2,4-Dichloro-5-methoxyphenyl)-2,3-dihydro-2-thioxo-4(1H)-quinazolinone CAS:338967-87-6
career henan chemical co
ATK CHEMICAL COMPANY LIMITED
Shenzhen Nexconn Pharmatechs Ltd
Hubei Jusheng Technology Co.,Ltd.
TargetMol Chemicals Inc.
Dideu Industries Group Limited
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
Nantong HI-FUTURE Biology Co., Ltd.
$1.00 /1KG
3-(2,4-Dichloro-5-methoxyphenyl)-2,3-dihydro-2-thioxo-4(1H)-quinazolinone CAS:338967-87-6
3-(2,4-Dichloro-5-methoxyphenyl)-2,3-dihydro-2-thioxo-4(1H)-quinazolinone CAS:338967-87-6