3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-TRIFLUOROMETHYLISOXAZOLE
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- $23 - $1050
- Product name: 3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-TRIFLUOROMETHYLISOXAZOLE
- CAS: 340267-36-9
- MF: C17H12F3NO3S
- MW: 367.34
- EINECS:
- MDL Number:MFCD05863975
- Synonyms:CAY10404;3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-TRIFLUOROMETHYLISOXAZOLE;3-(4-methylsulfonylphenyl)-4-phenyl-5-(trifluoromethyl)-1,2-oxazole;Isoxazole, 3-[4-(methylsulfonyl)phenyl]-4-phenyl-5-(trifluoromethyl)-;3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T;Bcl-XL,CAY10404,cancer,COX,anti-inflammatory,Bcl-2,Apoptosis,Akt,H-1703,Cyclooxygenase,NSCLC,CAY 10404,H-358,inhibit,cell,pGSK-3β,H-460,analgesic,MAPK,CAY-10404,cyclooxygenase-2,lung,anti-cancer,Inhibitor,Non-small,Protein kinase B,pAkt,PKB
10 prices
Selected condition：
Brand
- AK Scientific
- Cayman Chemical
- ChemScene
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- ManufacturerAK Scientific
- Product number7493CR
- Product description3-(4-Methylsulfonylphenyl)-4-phenyl-5-(trifluoromethyl)-1,2-oxazole
- Packaging50mg
- Price$950
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number70210
- Product descriptionCAY10404 ≥98%
- Packaging1mg
- Price$23
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number70210
- Product descriptionCAY10404 ≥98%
- Packaging5mg
- Price$100
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number70210
- Product descriptionCAY10404 ≥98%
- Packaging10mg
- Price$177
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number70210
- Product descriptionCAY10404 ≥98%
- Packaging50mg
- Price$765
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0082717
- Product descriptionCAY10404 99.79%
- Packaging5mg
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0082717
- Product descriptionCAY10404 99.79%
- Packaging10mg
- Price$180
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0082717
- Product descriptionCAY10404 99.79%
- Packaging25mg
- Price$380
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0082717
- Product descriptionCAY10404 99.79%
- Packaging50mg
- Price$650
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0082717
- Product descriptionCAY10404 99.79%
- Packaging100mg
- Price$1050
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 7493CR | 3-(4-Methylsulfonylphenyl)-4-phenyl-5-(trifluoromethyl)-1,2-oxazole | 50mg | $950 | 2021-12-16 | Buy |
| Cayman Chemical | 70210 | CAY10404 ≥98% | 1mg | $23 | 2024-03-01 | Buy |
| Cayman Chemical | 70210 | CAY10404 ≥98% | 5mg | $100 | 2024-03-01 | Buy |
| Cayman Chemical | 70210 | CAY10404 ≥98% | 10mg | $177 | 2024-03-01 | Buy |
| Cayman Chemical | 70210 | CAY10404 ≥98% | 50mg | $765 | 2024-03-01 | Buy |
| ChemScene | CS-0082717 | CAY10404 99.79% | 5mg | $100 | 2021-12-16 | Buy |
| ChemScene | CS-0082717 | CAY10404 99.79% | 10mg | $180 | 2021-12-16 | Buy |
| ChemScene | CS-0082717 | CAY10404 99.79% | 25mg | $380 | 2021-12-16 | Buy |
| ChemScene | CS-0082717 | CAY10404 99.79% | 50mg | $650 | 2021-12-16 | Buy |
| ChemScene | CS-0082717 | CAY10404 99.79% | 100mg | $1050 | 2021-12-16 | Buy |
Properties
storage temp. :Store at -20°C
solubility :DMSO:100.0(Max Conc. mg/mL);272.23(Max Conc. mM)
form :A crystalline solid
solubility :DMSO:100.0(Max Conc. mg/mL);272.23(Max Conc. mM)
form :A crystalline solid
Safety Information
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Description
Many non-steroidal anti-inflammatory drugs (NSAIDs) are potent but non-selective inhibitors of both COX-1 and COX-2 in humans. CAY10404 is one of the most selective inhibitors of COX-2 which has been reported to date, with a selectivity index (SI; SI = IC50 COX-1/IC50 COX-2) of >500,000. (The COX-1 IC50 is >500 mM, and COX-2 IC50 is <1 nM.) As a reference point, the SI of celecoxib is about 400. Thus, CAY10404 has an SI which is several logs greater than the first generation of selective COX-2 inhibitors, and is comparable to the SI of second generation selective COX-2 inhibitors, such as valdecoxib and etoricoxib.Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
InvivoChem
TargetMol Chemicals Inc.
Aladdin Scientific
Sichuan Wei Keqi Biological Technology Co., Ltd.
Shanghai Chaolan Chemical Technology Center
Beijing Solarbio Science & Tecnology Co., Ltd.
Beijing Jin Ming Biotechnology Co., Ltd.
Shanghai Hongye Biotechnology Co. Ltd
Hangzhou Synstar pharmaceutical Technology CO.,Ltd