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ChemicalBook >> CAS DataBase List >> N-2-Biphenylyl-7-nitro-2,1,3-benzoxadiazol-4-aMine

N-2-Biphenylyl-7-nitro-2,1,3-benzoxadiazol-4-aMine

N-2-Biphenylyl-7-nitro-2,1,3-benzoxadiazol-4-aMine price.
  • $18 - $2841
  • Product name: N-2-Biphenylyl-7-nitro-2,1,3-benzoxadiazol-4-aMine
  • CAS: 413611-93-5
  • MF: C18H12N4O3
  • MW: 332.31
  • EINECS:
  • MDL Number:MFCD00576774
  • Synonyms:N-2-Biphenylyl-7-nitro-2,1,3-benzoxadiazol-4-aMine;Biphenyl-2-yl-(7-nitrobenzo[1,2,5]oxadiazol-4-yl)amine;N-[1,1′-Biphenyl-2-yl]-7-nitro-2,1,3-Benzoxadiazol-4-amine;c-Myc Inhibitor II ;c-Myc Inhibitor II - CAS 413611-93-5 - Calbiochem;10074G5;10074 G5;10074-g;2,1,3-Benzoxadiazol-4-amine, N-[1,1'-biphenyl]-2-yl-7-nitro-
Price46 Properties Safety Information Description
46 prices
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  • aablocks
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  • AK Scientific
  • ApexBio Technology
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Package
  • 2mg
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  • 10mM*1mLinDMSO
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  • 10mM(1mLinDMSO)
  • 1mg
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  • 1G
  • Manufactureraablocks
  • Product numberAA00C0UR
  • Product descriptionN-[1,1'-biphenyl]-2-yl-7-nitro-2,1,3-benzoxadiazol-4-amine 99%
  • Packaging1mg
  • Price$18
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00C0UR
  • Product descriptionN-[1,1'-biphenyl]-2-yl-7-nitro-2,1,3-benzoxadiazol-4-amine 99%
  • Packaging5mg
  • Price$32
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00C0UR
  • Product descriptionN-[1,1'-biphenyl]-2-yl-7-nitro-2,1,3-benzoxadiazol-4-amine 99%
  • Packaging10mg
  • Price$46
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00C0UR
  • Product descriptionN-[1,1'-biphenyl]-2-yl-7-nitro-2,1,3-benzoxadiazol-4-amine 99%
  • Packaging25mg
  • Price$76
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00C0UR
  • Product descriptionN-[1,1'-biphenyl]-2-yl-7-nitro-2,1,3-benzoxadiazol-4-amine 99%
  • Packaging50mg
  • Price$113
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00C0UR
  • Product descriptionN-[1,1'-biphenyl]-2-yl-7-nitro-2,1,3-benzoxadiazol-4-amine 99%
  • Packaging100mg
  • Price$155
  • Updated2026-05-28
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  • ManufacturerACHEMBLOCK
  • Product numberQ65789
  • Product descriptionN-([1,1'-biphenyl]-2-yl)-7-nitrobenzo[c][1,2,5]oxadiazol-4-amine 98%
  • Packaging100MG
  • Price$240
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberQ65789
  • Product descriptionN-([1,1'-biphenyl]-2-yl)-7-nitrobenzo[c][1,2,5]oxadiazol-4-amine 98%
  • Packaging1G
  • Price$760
  • Updated2026-05-27
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  • ManufacturerAK Scientific
  • Product number0685BB
  • Product description4-Nitro-N-(2-phenylphenyl)-2,1,3-benzoxadiazol-7-amine
  • Packaging25mg
  • Price$320
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberC5722
  • Product description10074-G5
  • Packaging25mg
  • Price$185
  • Updated2026-05-06
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  • ManufacturerApexBio Technology
  • Product numberC5722
  • Product description10074-G5
  • Packaging5mg
  • Price$74
  • Updated2026-05-06
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  • ManufacturerApexBio Technology
  • Product numberC5722
  • Product description10074-G5
  • Packaging10mg
  • Price$109
  • Updated2026-05-06
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  • ManufacturerArctom
  • Product numberSLK-S8426
  • Product description10074-G5 99.44%
  • Packaging10mg
  • Price$140
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberSLK-S8426
  • Product description10074-G5 99.44%
  • Packaging10mM(1mLinDMSO)
  • Price$188
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberSLK-S8426
  • Product description10074-G5 99.44%
  • Packaging50mg
  • Price$378
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberSLK-S8426
  • Product description10074-G5 99.44%
  • Packaging200mg
  • Price$922
  • Updated2026-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00C0UR N-[1,1'-biphenyl]-2-yl-7-nitro-2,1,3-benzoxadiazol-4-amine 99% 1mg $18 2026-05-28 Buy
aablocks AA00C0UR N-[1,1'-biphenyl]-2-yl-7-nitro-2,1,3-benzoxadiazol-4-amine 99% 5mg $32 2026-05-28 Buy
aablocks AA00C0UR N-[1,1'-biphenyl]-2-yl-7-nitro-2,1,3-benzoxadiazol-4-amine 99% 10mg $46 2026-05-28 Buy
aablocks AA00C0UR N-[1,1'-biphenyl]-2-yl-7-nitro-2,1,3-benzoxadiazol-4-amine 99% 25mg $76 2026-05-28 Buy
aablocks AA00C0UR N-[1,1'-biphenyl]-2-yl-7-nitro-2,1,3-benzoxadiazol-4-amine 99% 50mg $113 2026-05-28 Buy
aablocks AA00C0UR N-[1,1'-biphenyl]-2-yl-7-nitro-2,1,3-benzoxadiazol-4-amine 99% 100mg $155 2026-05-28 Buy
ACHEMBLOCK Q65789 N-([1,1'-biphenyl]-2-yl)-7-nitrobenzo[c][1,2,5]oxadiazol-4-amine 98% 100MG $240 2026-05-27 Buy
ACHEMBLOCK Q65789 N-([1,1'-biphenyl]-2-yl)-7-nitrobenzo[c][1,2,5]oxadiazol-4-amine 98% 1G $760 2026-05-27 Buy
AK Scientific 0685BB 4-Nitro-N-(2-phenylphenyl)-2,1,3-benzoxadiazol-7-amine 25mg $320 2021-12-16 Buy
ApexBio Technology C5722 10074-G5 25mg $185 2026-05-06 Buy
ApexBio Technology C5722 10074-G5 5mg $74 2026-05-06 Buy
ApexBio Technology C5722 10074-G5 10mg $109 2026-05-06 Buy
Arctom SLK-S8426 10074-G5 99.44% 10mg $140 2026-05-26 Buy
Arctom SLK-S8426 10074-G5 99.44% 10mM(1mLinDMSO) $188 2026-05-26 Buy
Arctom SLK-S8426 10074-G5 99.44% 50mg $378 2026-05-26 Buy
Arctom SLK-S8426 10074-G5 99.44% 200mg $922 2026-05-26 Buy
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Properties

Boiling point :538.6±60.0 °C(Predicted)
Density :1.408±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: >10mg/mL
pka :-2.06±0.50(Predicted)
form :powder
color :red
InChI :1S/C18H12N4O3/c23-22(24)16-11-10-15(17-18(16)21-25-20-17)19-14-9-5-4-8-13(14)12-6-2-1-3-7-12/h1-11,19H
InChIKey :KMJPYSQOCBYMCF-UHFFFAOYSA-N
SMILES :[O-][N+](=O)c1ccc(Nc2ccccc2-c3ccccc3)c4nonc14

Safety Information

Symbol(GHS): Skull and Crossbones (GHS06)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger P264, P270, P301+P310, P321, P330,P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

The c-Myc oncoprotein is overexpressed in many tumors and is essential for maintaining the proliferation of transformed cells. To function as a transcription factor, c-Myc must dimerize with Max via the basic helix-loop-helix leucine zipper protein (bHLH-ZIP) domains in each protein. 10074-G5 is a c-Myc inhibitor that binds to and distorts the bHLH-ZIP domain of c-Myc (Kd = 2.8 μM), thereby inhibiting c-Myc/Max heterodimer formation and inhibiting its transcriptional activity (IC50 = 146 μM). 10074-G5 is cytotoxic to c-Myc-overexpressing cells lines with IC50 values of 15.6 and 13.5 μM for Daudi Burkitt lymphoma cells and HL60 promyelocytic leukemia cells, respectively. 10074-G5 can also interfere with N-Myc/Max interactions (Kd = 19.2 μM for binding the bHLH-Zip of N-Myc), inducing apoptosis in N-Myc amplified neuroblastoma Kelly cells (IC50 = 22.5 μM).

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Shanghai Boyle Chemical Co., Ltd. Tianjin heowns Biochemical Technology Co., Ltd. Guangzhou Isun Pharmaceutical Co., Ltd Sigma-Aldrich Shanghai Lollane Biological Technology Co.,Ltd. Struchem Co., Ltd. Shanghai YuanYe Biotechnology Co., Ltd. Target molecule Corp. Tianjin Kailiqi Biotechnology Co., Ltd. Shanghai SuperLan Chemcial Technique Centre