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ChemicalBook >> CAS DataBase List >> DEACETYLNORGESTIMATE (25 MG) ((E)- AND (Z)-17-DEACETYL NORGESTIMATE MIXTURE)

DEACETYLNORGESTIMATE (25 MG) ((E)- AND (Z)-17-DEACETYL NORGESTIMATE MIXTURE)

DEACETYLNORGESTIMATE (25 MG) ((E)- AND (Z)-17-DEACETYL NORGESTIMATE MIXTURE) price.
  • $120 - $1732.5
  • Product name: DEACETYLNORGESTIMATE (25 MG) ((E)- AND (Z)-17-DEACETYL NORGESTIMATE MIXTURE)
  • CAS: 53016-31-2
  • MF: C21H29NO2
  • MW: 327.46
  • EINECS:
  • MDL Number:MFCD03695603
  • Synonyms:(17α)-13-Ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one OxiMe;(17α)-13-Ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one-d6 OxiMe;(-)-NorelgestroMin-d6;(17alpha)-13-Ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one oxime;(E)- and (Z)-17-Deacetylnorgestimate mixture;Norgestimate metabolite Norelgestromin;17-Desacetyl Norgestimate ((E)- AND (Z)-17-DEACETYL NORGESTIMATE MIXTURE);Deacetylnorgestimate (Mixture of (E)- And (Z)-17-Deacetyl Norgestimate)
10 prices
Selected condition:
Brand
  • American Custom Chemicals Corporation
  • ChemScene
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
Package
  • 5MG
  • 10MG
  • 25mg
  • 50mg
  • 100MG
  • 200mg
  • 250mg
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberMTB0002492
  • Product description18-METHYLNORETHINDRONE OXIME 95.00%
  • Packaging5MG
  • Price$452.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0000144
  • Product description17-DESACETYL NORGESTIMATE 95.00%
  • Packaging10MG
  • Price$721.88
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0000144
  • Product description17-DESACETYL NORGESTIMATE 95.00%
  • Packaging100MG
  • Price$1732.5
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4097
  • Product descriptionNorgestimatemetaboliteNorelgestromin 99.79%
  • Packaging5mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4097
  • Product descriptionNorgestimatemetaboliteNorelgestromin 99.79%
  • Packaging10mg
  • Price$168
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4097
  • Product descriptionNorgestimatemetaboliteNorelgestromin 99.79%
  • Packaging50mg
  • Price$720
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number8887
  • Product description17-Desacetyl norgestimate
  • Packaging50mg
  • Price$290
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number1468454
  • Product descriptionDeacetylnorgestimate
  • Packaging200mg
  • Price$710
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number1471958
  • Product descriptionDeacetylnorgestimate
  • Packaging25mg
  • Price$1240
  • Updated2022-05-15
  • Buy
  • ManufacturerTRC
  • Product numberD288721
  • Product description(E/Z)-17-Deacetylnorgestimate
  • Packaging250mg
  • Price$1260
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation MTB0002492 18-METHYLNORETHINDRONE OXIME 95.00% 5MG $452.5 2021-12-16 Buy
American Custom Chemicals Corporation API0000144 17-DESACETYL NORGESTIMATE 95.00% 10MG $721.88 2021-12-16 Buy
American Custom Chemicals Corporation API0000144 17-DESACETYL NORGESTIMATE 95.00% 100MG $1732.5 2021-12-16 Buy
ChemScene CS-4097 NorgestimatemetaboliteNorelgestromin 99.79% 5mg $120 2021-12-16 Buy
ChemScene CS-4097 NorgestimatemetaboliteNorelgestromin 99.79% 10mg $168 2021-12-16 Buy
ChemScene CS-4097 NorgestimatemetaboliteNorelgestromin 99.79% 50mg $720 2021-12-16 Buy
Medical Isotopes, Inc. 8887 17-Desacetyl norgestimate 50mg $290 2021-12-16 Buy
Sigma-Aldrich 1468454 Deacetylnorgestimate 200mg $710 2024-03-01 Buy
Sigma-Aldrich 1471958 Deacetylnorgestimate 25mg $1240 2022-05-15 Buy
TRC D288721 (E/Z)-17-Deacetylnorgestimate 250mg $1260 2021-12-16 Buy

Properties

Melting point :107-109°C
Boiling point :491.9±45.0 °C(Predicted)
Density :1.23±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :DMF: 11 mg/ml; DMSO: 10 mg/ml; Ethanol: 12 mg/ml; PBS (pH 7.2): 0.25 mg/ml
form :A solid
pka :12.22±0.60(Predicted)
CAS DataBase Reference :53016-31-2

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P201 Obtain special instructions before use.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Ortho Evra@ is the first birth control transdermal patch and contains a combination of norelgestromin and ethinylestradiol. The patch can be applied to the buttocks, lower abdomen, upper torso or arms; changed weekly for 3 weeks, followed by a patch-free week. Norelgestromin is the active metabolite produced following oral administration of norgestimate, the progestin component of the contraceptive, Ortho-Cyclen?. The half-life value of norelgestromin was approximately 28 h. Following application, norelgestromin rapidly appeared in the serum, reached a plateau by approximately 48h and was maintained at an approximate steady state throughout the wear period. Hepatic metabolites of norelgestromin included norgestrel and various hydroxylated and conjugated metabolites that were eliminated by renal and fecal pathways. Ortho Evra produced ovarian suppression and cycle control. It was significantly more effective in suppressing follicular development than the leading oral contraceptive Triphasil? (ethinyl estradiol/levomorgestrel); was as effective in preventing pregnancies and had similar tolerability profile. The patch offers 99% efficacy when used appropriately, as shown by three clinical trials. However, a statistically significantly greater proportion of pregnancies occurred among women weighing 90 kg or more. Ortho Evra? was well tolerated, with 2.6% of women discontinuing treatment due to mild to moderate reactions at the site of application. Thus, the patch combined the efficacy of oral contraceptives with the convenience of just once-weekly dosing.

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