1,3,5[10]-Estratriene-3,16alpha-diol-17-one
![1,3,5[10]-Estratriene-3,16alpha-diol-17-one price.](/CAS/GIF/566-76-7.gif)
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- $120 - $2960
- Product name: 1,3,5[10]-Estratriene-3,16alpha-diol-17-one
- CAS: 566-76-7
- MF: C18H22O3
- MW: 286.37
- EINECS:
- MDL Number:MFCD00870436
- Synonyms:1,3,5(10)-ESTRATRIEN-3,16-ALPHA-DIOL-17-ONE;3,16ALPHA-DIHYDROXY-1,3,5[10]-ESTRATRIEN-17-ONE;(16R)-3,16α-Dihydroxy-1,3,5(10)-estratriene-17-one;16α-OHE1;3,16α-Dihydroxy-1,3,5(10)-estratrien-17-one;C05300;(16α)-3,16-Dihydroxyestra-1,3,5(10)-trien-17-one;Estra-1,3,5(10)-triene-3,16α-diol-17-one
30 prices
Selected condition：
Brand
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- Biosynth
- Cayman Chemical
- ChemScene
- IsoSciences
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 2mg
- 2.5MG
- 1MG
- 1mL(100ug/mL)
- 5MG
- 10mg
- 25MG
- 50mg
- 100mg
- 1ML
- ManufacturerACHEMBLOCK
- Product numberX211455
- Product description16Alpha-Hydroxyestrone 98%
- Packaging5MG
- Price$625
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberX211455
- Product description16Alpha-Hydroxyestrone 98%
- Packaging25MG
- Price$2015
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberZ1964
- Product description16-HydroxyEstrone
- Packaging10mg
- Price$835
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberSHG0007053
- Product description1,3,5[10]-ESTRATRIENE-3,16-ALPHA-DIOL-17-ONE 95.00%
- Packaging25MG
- Price$1400
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberSHG0007053
- Product description1,3,5[10]-ESTRATRIENE-3,16-ALPHA-DIOL-17-ONE 95.00%
- Packaging1MG
- Price$485
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberSHG0007053
- Product description1,3,5[10]-ESTRATRIENE-3,16-ALPHA-DIOL-17-ONE 95.00%
- Packaging2.5MG
- Price$525
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberFH59537
- Product description16a-Hydroxy estrone
- Packaging1mg
- Price$900
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberFH59537
- Product description16a-Hydroxy estrone
- Packaging2mg
- Price$900
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberFH59537
- Product description16a-Hydroxy estrone
- Packaging5mg
- Price$908.6
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberFH59537
- Product description16a-Hydroxy estrone
- Packaging10mg
- Price$1427.8
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberFH59537
- Product description16a-Hydroxy estrone
- Packaging25mg
- Price$2758.25
- Updated2026-06-04
- Buy
- ManufacturerCayman Chemical
- Product number15208
- Product description16α-hydroxy Estrone ≥98%
- Packaging5mg
- Price$466
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number15208
- Product description16α-hydroxy Estrone ≥98%
- Packaging10mg
- Price$729
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number15208
- Product description16α-hydroxy Estrone ≥98%
- Packaging1mg
- Price$134
- Updated2026-04-30
- Buy
- ManufacturerChemScene
- Product numberCS-0061863
- Product description16α-Hydroxyestrone ≥98%
- Packaging5mg
- Price$360
- Updated2026-06-04
- Buy
- ManufacturerChemScene
- Product numberCS-0061863
- Product description16α-Hydroxyestrone ≥98%
- Packaging1mg
- Price$120
- Updated2026-06-04
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| ACHEMBLOCK | X211455 | 16Alpha-Hydroxyestrone 98% | 5MG | $625 | 2026-05-27 | Buy |
| ACHEMBLOCK | X211455 | 16Alpha-Hydroxyestrone 98% | 25MG | $2015 | 2026-05-27 | Buy |
| AK Scientific | Z1964 | 16-HydroxyEstrone | 10mg | $835 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | SHG0007053 | 1,3,5[10]-ESTRATRIENE-3,16-ALPHA-DIOL-17-ONE 95.00% | 25MG | $1400 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | SHG0007053 | 1,3,5[10]-ESTRATRIENE-3,16-ALPHA-DIOL-17-ONE 95.00% | 1MG | $485 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | SHG0007053 | 1,3,5[10]-ESTRATRIENE-3,16-ALPHA-DIOL-17-ONE 95.00% | 2.5MG | $525 | 2021-12-16 | Buy |
| Biosynth | FH59537 | 16a-Hydroxy estrone | 1mg | $900 | 2026-06-04 | Buy |
| Biosynth | FH59537 | 16a-Hydroxy estrone | 2mg | $900 | 2026-06-04 | Buy |
| Biosynth | FH59537 | 16a-Hydroxy estrone | 5mg | $908.6 | 2026-06-04 | Buy |
| Biosynth | FH59537 | 16a-Hydroxy estrone | 10mg | $1427.8 | 2026-06-04 | Buy |
| Biosynth | FH59537 | 16a-Hydroxy estrone | 25mg | $2758.25 | 2026-06-04 | Buy |
| Cayman Chemical | 15208 | 16α-hydroxy Estrone ≥98% | 5mg | $466 | 2026-04-30 | Buy |
| Cayman Chemical | 15208 | 16α-hydroxy Estrone ≥98% | 10mg | $729 | 2026-04-30 | Buy |
| Cayman Chemical | 15208 | 16α-hydroxy Estrone ≥98% | 1mg | $134 | 2026-04-30 | Buy |
| ChemScene | CS-0061863 | 16α-Hydroxyestrone ≥98% | 5mg | $360 | 2026-06-04 | Buy |
| ChemScene | CS-0061863 | 16α-Hydroxyestrone ≥98% | 1mg | $120 | 2026-06-04 | Buy |
Properties
Melting point :209-211°C
Boiling point :493.2±45.0 °C(Predicted)
Density :1.249±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
form :Solid
pka :10.23±0.60(Predicted)
color :White to Light Beige
Boiling point :493.2±45.0 °C(Predicted)
Density :1.249±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
form :Solid
pka :10.23±0.60(Predicted)
color :White to Light Beige
Safety Information
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| Signal word: | Danger | |||||||||||||||||||||
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Description
The naturally-occurring estrogens are estrone (E1, ), estradiol (E2, ), and estriol (E3, ). 16α-hydroxy Estrone (16α-OHE1) is a hydroxylated metabolite of E1 as well as an interconversion product with E2. E1 is 16α-hydroxylated by cytochrome P450 (CYP) isoforms, including CYP1A1, CYP3A5, CYP3A4, and CYP3A7, with CYP3A5 being breast-specific. 16α-OHE1 is sulphatized or glucuronidated before excretion. It is increased in rheumatoid arthritis and decreased by physical activity. Unlike the parent estrogens and other hydroxylated metabolites of E1, 16α-OHE1 binds covalently and persistently activates estrogen receptors. In addition, this metabolite increases cell proliferation and does not suppress TNF-α secretion, whereas other estrogen metabolites are not pro-proliferative and have marked effects on TNF-α secretion. The levels of 16α-OHE1 are increased in some forms of hormone therapy. Because hormone therapy increases breast cancer risk, 16α-OHE1 has been implicated as a risk factor for breast cancer, although supportive data remains elusive.Related product price
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Suppliers and manufacturers
J & K SCIENTIFIC LTD.
Chemsky（shanghai）International Co.,Ltd.
Clearsynth Labs Limited
Alta Scientific Co., Ltd.
Shanghai YuanYe Biotechnology Co., Ltd.
Shanghai Hongye Biotechnology Co. Ltd
Shenzhen Polymeri Biochemical Technology Co., Ltd.
BOC Sciences
Dayang Chem (Hangzhou) Co.,Ltd.
Yangzhou Changhua Biotechnology Co., Ltd.