4-AMINO-5-CYANO-7-(BETA-D-RIBOFURANOSYL)PYRROLO[2,3-D]PYRIMIDINE
![4-AMINO-5-CYANO-7-(BETA-D-RIBOFURANOSYL)PYRROLO[2,3-D]PYRIMIDINE price.](/CAS/GIF/606-58-6.gif)
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- $20 - $1300
- Product name: 4-AMINO-5-CYANO-7-(BETA-D-RIBOFURANOSYL)PYRROLO[2,3-D]PYRIMIDINE
- CAS: 606-58-6
- MF: C12H13N5O4
- MW: 291.26
- EINECS:
- MDL Number:MFCD00866513
- Synonyms:NSC 63701;NSC 99843;3-d)pyrimidine-5-carbonitrile,4-amino-7-beta-d-ribofuranosyl-7h-pyrrolo( ;4-amino-5-cyano-7-(d-ribofuranosyl)-7h-pyrrolo(2,3-d)pyrimidine ;4-amino-7-beta-d-ribofuranosyl-7h-pyrrolo(2,3-d)pyrimidine-5-carbonitrile ;a-399-y4 ;ahygroscopin-b ;antibiotic1037
69 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10
- 1mg
- 5mg
- 10mg
- 25MG
- 50
- 50mg
- 10mM*1mLinDMSO(Solution)
- 10mM*1mLinDMSO(Solid+Solvent)
- 100MG
- 250mg
- 1g
- Manufactureraablocks
- Product numberAA019FTP
- Product description4-Amino-7-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile 98%LCMS
- Packaging5mg
- Price$29
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA019FTP
- Product description4-Amino-7-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile 98%LCMS
- Packaging10mg
- Price$44
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA019FTP
- Product description4-Amino-7-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile 98%LCMS
- Packaging1mg
- Price$20
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA019FTP
- Product description4-Amino-7-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile 98
- Packaging50mg
- Price$191
- Updated2026-05-29
- Buy
- ManufacturerACHEMBLOCK
- Product numberZ238354
- Product descriptionToyocamycin 98%
- Packaging25MG
- Price$135
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberZ238354
- Product descriptionToyocamycin 98%
- Packaging100MG
- Price$445
- Updated2026-05-27
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0015849
- Product description4-AMINO-7-BETA-D-RIBOFURANOSYL-7H-PYRROLO[2,3-D]PYRIMIDINE-5-CARBONITRILE 95.00%
- Packaging10MG
- Price$197.4
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7795
- Product descriptionToyocamycin
- Packaging50mg
- Price$410
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7795
- Product descriptionToyocamycin
- Packaging10mg
- Price$91
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB7795
- Product descriptionToyocamycin
- Packaging5mg
- Price$60
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB7795
- Product descriptionToyocamycin
- Packaging100mg
- Price$546
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB7795
- Product descriptionToyocamycin
- Packaging50mg
- Price$315
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberHY-103248
- Product descriptionToyocamycin 99.27%
- Packaging25mg
- Price$155
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-103248
- Product descriptionToyocamycin 99.27%
- Packaging10mg
- Price$72
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-103248
- Product descriptionToyocamycin 99.27%
- Packaging10mM*1mLinDMSO(Solid+Solvent)
- Price$50
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-103248
- Product descriptionToyocamycin 99.27%
- Packaging10mM*1mLinDMSO(Solution)
- Price$53
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA019FTP | 4-Amino-7-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile 98%LCMS | 5mg | $29 | 2026-05-29 | Buy |
| aablocks | AA019FTP | 4-Amino-7-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile 98%LCMS | 10mg | $44 | 2026-05-29 | Buy |
| aablocks | AA019FTP | 4-Amino-7-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile 98%LCMS | 1mg | $20 | 2026-05-29 | Buy |
| aablocks | AA019FTP | 4-Amino-7-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile 98 | 50mg | $191 | 2026-05-29 | Buy |
| ACHEMBLOCK | Z238354 | Toyocamycin 98% | 25MG | $135 | 2026-05-27 | Buy |
| ACHEMBLOCK | Z238354 | Toyocamycin 98% | 100MG | $445 | 2026-05-27 | Buy |
| American Custom Chemicals Corporation | API0015849 | 4-AMINO-7-BETA-D-RIBOFURANOSYL-7H-PYRROLO[2,3-D]PYRIMIDINE-5-CARBONITRILE 95.00% | 10MG | $197.4 | 2021-12-16 | Buy |
| ApexBio Technology | B7795 | Toyocamycin | 50mg | $410 | 2021-12-16 | Buy |
| ApexBio Technology | B7795 | Toyocamycin | 10mg | $91 | 2026-05-06 | Buy |
| ApexBio Technology | B7795 | Toyocamycin | 5mg | $60 | 2026-05-06 | Buy |
| ApexBio Technology | B7795 | Toyocamycin | 100mg | $546 | 2026-05-06 | Buy |
| ApexBio Technology | B7795 | Toyocamycin | 50mg | $315 | 2026-05-06 | Buy |
| Arctom | HY-103248 | Toyocamycin 99.27% | 25mg | $155 | 2026-05-26 | Buy |
| Arctom | HY-103248 | Toyocamycin 99.27% | 10mg | $72 | 2026-05-26 | Buy |
| Arctom | HY-103248 | Toyocamycin 99.27% | 10mM*1mLinDMSO(Solid+Solvent) | $50 | 2026-05-26 | Buy |
| Arctom | HY-103248 | Toyocamycin 99.27% | 10mM*1mLinDMSO(Solution) | $53 | 2026-05-26 | Buy |
Properties
Melting point :243°; mp 239-243°
alpha :D16 -45.7° (c = 1.05 in 0.1N HCl)
Boiling point :433.28°C (rough estimate)
Density :1.3067 (rough estimate)
refractive index :1.7000 (estimate)
storage temp. :2-8°C
solubility :DMSO: soluble0.90 - 1.10mg/mL, clear, colorless
form :solid
pka :12.31±0.70(Predicted)
color :White or off-white
biological source :Streptomyces rimosus
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChI :InChI=1/C12H13N5O4/c13-1-5-2-17(11-7(5)10(14)15-4-16-11)12-9(20)8(19)6(3-18)21-12/h2,4,6,8-9,12,18-20H,3H2,(H2,14,15,16)/t6-,8-,9-,12-/s3
InChIKey :XOKJUSAYZUAMGJ-SMUHWEKINA-N
SMILES :N1(C=C(C#N)C2C(N)=NC=NC1=2)[C@H]1[C@H](O)[C@H](O)[C@@H](CO)O1 |&1:12,13,15,17,r|
alpha :D16 -45.7° (c = 1.05 in 0.1N HCl)
Boiling point :433.28°C (rough estimate)
Density :1.3067 (rough estimate)
refractive index :1.7000 (estimate)
storage temp. :2-8°C
solubility :DMSO: soluble0.90 - 1.10mg/mL, clear, colorless
form :solid
pka :12.31±0.70(Predicted)
color :White or off-white
biological source :Streptomyces rimosus
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChI :InChI=1/C12H13N5O4/c13-1-5-2-17(11-7(5)10(14)15-4-16-11)12-9(20)8(19)6(3-18)21-12/h2,4,6,8-9,12,18-20H,3H2,(H2,14,15,16)/t6-,8-,9-,12-/s3
InChIKey :XOKJUSAYZUAMGJ-SMUHWEKINA-N
SMILES :N1(C=C(C#N)C2C(N)=NC=NC1=2)[C@H]1[C@H](O)[C@H](O)[C@@H](CO)O1 |&1:12,13,15,17,r|
Safety Information
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Description
Toyocamycin is a natural adenosine analog first isolated from Streptomyces and shown in early studies to be cytotoxic to bacteria, fungi, and cancer cells and to have antiviral activities. Toyocamycin prevents IRE1α-induced mRNA cleavage (IC50 = 80 nM) and inhibits constitutive activation of XBP1 in multiple myeloma cell lines. It is used to study IRE1α action in the endoplasmic reticulum stress response, particularly in the context of cancer. It also inhibits phosphatidylinositol kinase in vitro (IC50 = 3.3 μg/ml), but not in cells, and blocks the ribosomal RNA-processing kinase Rio1 (IC50 = ~30 nM).More related product prices
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