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ChemicalBook >> CAS DataBase List >> 680C91

680C91

680C91 price.
  • $47 - $3120
  • Product name: 680C91
  • CAS: 163239-22-3
  • MF: C15H11FN2
  • MW: 238.26
  • EINECS:
  • MDL Number:MFCD20926361
  • Synonyms:680C91;1H-Indole, 6-fluoro-3-[(1E)-2-(3-pyridinyl)ethenyl]-;6-Fluoro-3-[(1E)-2-(3-pyridinyl)ethenyl)-1H-indole;680C91 >=98% (HPLC);6-fluoro-3-[(E)-2-(pyridin-3-yl)ethenyl]-1H-indole;inhibit,Inhibitor,680C91,tryptophan 2,3-dioxygenasetryptophan catabolismAlzheimer’s Disease,680C-91;(E)-6-fluoro-3-(2-(pyridin-3-yl)vinyl)-1H-indole;680C91, tryptophan 2,3-dioxygenase inhibitor
Price38 Properties Safety Information Description
38 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 2.5mg
  • 10mM(1mLinDMSO)
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250MG
  • 500mg
  • 1000mg
  • 1g
  • Manufactureraablocks
  • Product numberAA001TUR
  • Product description(E)-6-Fluoro-3-(2-(pyridin-3-yl)vinyl)-1H-indole
  • Packaging2mg
  • Price$47
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001TUR
  • Product description(E)-6-Fluoro-3-(2-(pyridin-3-yl)vinyl)-1H-indole
  • Packaging5mg
  • Price$61
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001TUR
  • Product description(E)-6-Fluoro-3-(2-(pyridin-3-yl)vinyl)-1H-indole
  • Packaging10mg
  • Price$88
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001TUR
  • Product description(E)-6-Fluoro-3-(2-(pyridin-3-yl)vinyl)-1H-indole
  • Packaging25mg
  • Price$155
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001TUR
  • Product description(E)-6-Fluoro-3-(2-(pyridin-3-yl)vinyl)-1H-indole
  • Packaging50mg
  • Price$238
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001TUR
  • Product description(E)-6-Fluoro-3-(2-(pyridin-3-yl)vinyl)-1H-indole
  • Packaging100mg
  • Price$337
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberU131869
  • Product description6-Fluoro-3-[(E)-2-(3-pyridinyl)vinyl]-1H-indole 95%
  • Packaging100MG
  • Price$475
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberU131869
  • Product description6-Fluoro-3-[(E)-2-(3-pyridinyl)vinyl]-1H-indole 95%
  • Packaging250MG
  • Price$950
  • Updated2026-05-27
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0001271
  • Product description6-FLUORO-3-[(1E)-2-(3-PYRIDINYL)ETHENYL]-1H-INDOLE 95.00%
  • Packaging50MG
  • Price$1269.35
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0001271
  • Product description6-FLUORO-3-[(1E)-2-(3-PYRIDINYL)ETHENYL]-1H-INDOLE 95.00%
  • Packaging10MG
  • Price$744.98
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5573
  • Product description680C91
  • Packaging25mg
  • Price$736
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5573
  • Product description680C91
  • Packaging50mg
  • Price$1329
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5573
  • Product description680C91
  • Packaging10mg
  • Price$308
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5573
  • Product description680C91
  • Packaging5mg
  • Price$200
  • Updated2026-05-06
  • Buy
  • ManufacturerArctom
  • Product numberSLK-S8997
  • Product description680C91 99.64%
  • Packaging10mM(1mLinDMSO)
  • Price$188
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberSLK-S8997
  • Product description680C91 99.64%
  • Packaging5mg
  • Price$140
  • Updated2026-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA001TUR (E)-6-Fluoro-3-(2-(pyridin-3-yl)vinyl)-1H-indole 2mg $47 2026-05-28 Buy
aablocks AA001TUR (E)-6-Fluoro-3-(2-(pyridin-3-yl)vinyl)-1H-indole 5mg $61 2026-05-28 Buy
aablocks AA001TUR (E)-6-Fluoro-3-(2-(pyridin-3-yl)vinyl)-1H-indole 10mg $88 2026-05-28 Buy
aablocks AA001TUR (E)-6-Fluoro-3-(2-(pyridin-3-yl)vinyl)-1H-indole 25mg $155 2026-05-28 Buy
aablocks AA001TUR (E)-6-Fluoro-3-(2-(pyridin-3-yl)vinyl)-1H-indole 50mg $238 2026-05-28 Buy
aablocks AA001TUR (E)-6-Fluoro-3-(2-(pyridin-3-yl)vinyl)-1H-indole 100mg $337 2026-05-28 Buy
ACHEMBLOCK U131869 6-Fluoro-3-[(E)-2-(3-pyridinyl)vinyl]-1H-indole 95% 100MG $475 2026-05-27 Buy
ACHEMBLOCK U131869 6-Fluoro-3-[(E)-2-(3-pyridinyl)vinyl]-1H-indole 95% 250MG $950 2026-05-27 Buy
American Custom Chemicals Corporation INB0001271 6-FLUORO-3-[(1E)-2-(3-PYRIDINYL)ETHENYL]-1H-INDOLE 95.00% 50MG $1269.35 2021-12-16 Buy
American Custom Chemicals Corporation INB0001271 6-FLUORO-3-[(1E)-2-(3-PYRIDINYL)ETHENYL]-1H-INDOLE 95.00% 10MG $744.98 2021-12-16 Buy
ApexBio Technology B5573 680C91 25mg $736 2026-05-06 Buy
ApexBio Technology B5573 680C91 50mg $1329 2021-12-16 Buy
ApexBio Technology B5573 680C91 10mg $308 2021-12-16 Buy
ApexBio Technology B5573 680C91 5mg $200 2026-05-06 Buy
Arctom SLK-S8997 680C91 99.64% 10mM(1mLinDMSO) $188 2026-05-26 Buy
Arctom SLK-S8997 680C91 99.64% 5mg $140 2026-05-26 Buy
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Properties

Boiling point :431.2±35.0 °C(Predicted)
Density :1.305±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥10mg/mL
pka :15.92±0.30(Predicted)
form :powder
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChI :1S/C15H11FN2/c16-13-5-6-14-12(10-18-15(14)8-13)4-3-11-2-1-7-17-9-11/h1-10,18H/b4-3+
InChIKey :YBSDQTBCNYWBMX-ONEGZZNKSA-N
SMILES :Fc1ccc2c(\C=C\c3cccnc3)c[nH]c2c1

Safety Information

Symbol(GHS): Corrosion (GHS05)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger P280, P305+P351+P338, P310
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

680C91 (163239-22-3) is a potent and selective inhibitor of tryptophan 2,3-dioxygenase (TDO) Ki=42 nM).1,2Displays no activity against indoleamine 2,3-dioxygenase, MAO-A and B and does not effect serotonin uptake. Elevates CSF tryptophan by up to 260% and CSF serotonin by 170% of basal.2TDO inhibition by 680C91 in glioma cells blocked the release of kynurenine (Cat.# 10-2666), an endogenous tumor promoting AHR ligand.4

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Suppliers and manufacturers

Nanjing Chemlin Chemical Co., Ltd Nanjing Dulai Biotechnology Co., Ltd. Hangzhou J&H Chemical Co., Ltd. Sigma-Aldrich Shanghai Lollane Biological Technology Co.,Ltd. Shanghai Beckham Medical Technology Co., Ltd EMMX Biotechnology LLC Shanghai YuanYe Biotechnology Co., Ltd. Tianjin Kailiqi Biotechnology Co., Ltd. Shanghai Chaolan Chemical Technology Center