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ChemicalBook >> CAS DataBase List >> N-{4-chloro-2-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]phenyl}-2-hydroxybenzamide

N-{4-chloro-2-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]phenyl}-2-hydroxybenzamide

N-{4-chloro-2-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]phenyl}-2-hydroxybenzamide price.
  • $32 - $1800
  • Product name: N-{4-chloro-2-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]phenyl}-2-hydroxybenzamide
  • CAS: 693288-97-0
  • MF: C22H15ClN2O4
  • MW: 406.82
  • EINECS:
  • MDL Number:MFCD12912405
  • Synonyms:N-{4-chloro-2-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]phenyl}-2-hydroxybenzamide;N-[4-Chloro-2-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)methyl]phenyl]-2-hydroxybenzamide;N-[4-Chloro-2-(phthalimidomethyl)phenyl]salicylamide;CPPHA;N-[4-chloro-2-[(1,3-dioxoisoindol-2-yl)methyl]phenyl]-2-hydroxybenzamide;Benzamide, N-[4-chloro-2-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)methyl]phenyl]-2-hydroxy-;CPPHA, 10 mM in DMSO
Price52 Properties Safety Information Description
52 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Tocris
  • TRC
  • Usbiological
Package
  • 1mg
  • 10mg
  • 5mg
  • 10mM*1mLinDMSO(Solution)
  • 10
  • 25mg
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • Manufactureraablocks
  • Product numberAA00FBWX
  • Product descriptionCPPHA 99%
  • Packaging50mg
  • Price$143
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00FBWX
  • Product descriptionCPPHA 99%
  • Packaging100mg
  • Price$245
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00FBWX
  • Product descriptionCPPHA 99%
  • Packaging25mg
  • Price$86
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00FBWX
  • Product descriptionCPPHA
  • Packaging5mg
  • Price$44
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00FBWX
  • Product descriptionCPPHA ≥98%
  • Packaging1mg
  • Price$36
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY226016
  • Product descriptionCPPHA 97.00%
  • Packaging100MG
  • Price$955
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY226016
  • Product descriptionCPPHA 97.00%
  • Packaging25MG
  • Price$365
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number3562AH
  • Product descriptionN-[4-Chloro-2-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]phenyl]-2-hydroxybenzamide
  • Packaging50mg
  • Price$640
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3562AH
  • Product descriptionN-[4-Chloro-2-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]phenyl]-2-hydroxybenzamide
  • Packaging10mg
  • Price$218
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0035901
  • Product descriptionN-[4-CHLORO-2-[(1,3-DIOXO-1,3-DIHYDRO-2H-ISOINDOL-2-YL)METHYL]PHENYL]-2-HYDROXYBENZAMIDE 95.00%
  • Packaging25MG
  • Price$1507.74
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0035901
  • Product descriptionN-[4-CHLORO-2-[(1,3-DIOXO-1,3-DIHYDRO-2H-ISOINDOL-2-YL)METHYL]PHENYL]-2-HYDROXYBENZAMIDE 95.00%
  • Packaging5MG
  • Price$839.86
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3333
  • Product descriptionCPPHA
  • Packaging10mg
  • Price$138
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3333
  • Product descriptionCPPHA
  • Packaging5mg
  • Price$90
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3333
  • Product descriptionCPPHA
  • Packaging50mg
  • Price$501
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3333
  • Product descriptionCPPHA
  • Packaging10mg
  • Price$221
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberHY-14612
  • Product descriptionCPPHA 98.06%
  • Packaging50mg
  • Price$371
  • Updated2026-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00FBWX CPPHA 99% 50mg $143 2026-05-28 Buy
aablocks AA00FBWX CPPHA 99% 100mg $245 2026-05-28 Buy
aablocks AA00FBWX CPPHA 99% 25mg $86 2026-05-28 Buy
aablocks AA00FBWX CPPHA 5mg $44 2026-05-28 Buy
aablocks AA00FBWX CPPHA ≥98% 1mg $36 2026-05-28 Buy
ACHEMBLOCK Y226016 CPPHA 97.00% 100MG $955 2026-05-27 Buy
ACHEMBLOCK Y226016 CPPHA 97.00% 25MG $365 2026-05-27 Buy
AK Scientific 3562AH N-[4-Chloro-2-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]phenyl]-2-hydroxybenzamide 50mg $640 2021-12-16 Buy
AK Scientific 3562AH N-[4-Chloro-2-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]phenyl]-2-hydroxybenzamide 10mg $218 2021-12-16 Buy
American Custom Chemicals Corporation HCH0035901 N-[4-CHLORO-2-[(1,3-DIOXO-1,3-DIHYDRO-2H-ISOINDOL-2-YL)METHYL]PHENYL]-2-HYDROXYBENZAMIDE 95.00% 25MG $1507.74 2021-12-16 Buy
American Custom Chemicals Corporation HCH0035901 N-[4-CHLORO-2-[(1,3-DIOXO-1,3-DIHYDRO-2H-ISOINDOL-2-YL)METHYL]PHENYL]-2-HYDROXYBENZAMIDE 95.00% 5MG $839.86 2021-12-16 Buy
ApexBio Technology A3333 CPPHA 10mg $138 2026-05-06 Buy
ApexBio Technology A3333 CPPHA 5mg $90 2026-05-06 Buy
ApexBio Technology A3333 CPPHA 50mg $501 2026-05-06 Buy
ApexBio Technology A3333 CPPHA 10mg $221 2021-12-16 Buy
Arctom HY-14612 CPPHA 98.06% 50mg $371 2026-05-26 Buy
Next Last

Properties

Boiling point :539.7±50.0 °C(Predicted)
Density :1.505
storage temp. :-20°C
solubility :DMSO: >20mg/mL
form :solid
pka :8.24±0.30(Predicted)
color :Light yellow to yellow

Safety Information

Symbol(GHS): Environment (GHS09)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning P273, P391, P501
Precautionary statements:
P273 Avoid release to the environment.
P501 Dispose of contents/container to..…

Description

CPPHA is a positive allosteric modulator of metabotropic glutamate receptor 5 (mGluR5) that potentiates human and rat mGluR5 activation by glutamate, 3,5-DHPG , and quisqualate (EC50s = 0.316-0.5 and 0.634-1.16 μM for human and rat mGluR5, respectively). It is selective for mGluR5 over other mGluRs but exhibits submicromolar activity at PDE6, δ- and κ-opioid receptors, and the ether-a-go-go related gene (ERG) potassium channel (Kis = 500, 352, 474, and 813 nM, respectively). CPPHA potentiates 3,5-DHPG-induced NMDA currents in CA1 pyramidal cells and the depolarization of rat subthalamic nucleus (STN) neurons.

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