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ChemicalBook >> CAS DataBase List >> Cyclohexyl-[2-(3,5-dimethyl-pyrazol-1-yl)-6-methyl-pyrimidin-4-yl]-amine

Cyclohexyl-[2-(3,5-dimethyl-pyrazol-1-yl)-6-methyl-pyrimidin-4-yl]-amine

Cyclohexyl-[2-(3,5-dimethyl-pyrazol-1-yl)-6-methyl-pyrimidin-4-yl]-amine price.
  • $67 - $1219
  • Product name: Cyclohexyl-[2-(3,5-dimethyl-pyrazol-1-yl)-6-methyl-pyrimidin-4-yl]-amine
  • CAS: 73029-73-9
  • MF: C16H23N5
  • MW: 285.39
  • EINECS:
  • MDL Number:MFCD01550586
  • Synonyms:Cyclohexyl-[2-(3,5-dimethyl-pyrazol-1-yl)-6-methyl-pyrimidin-4-yl]-amine;N-Cyclohexyl-N-[2-(3,5-dimethyl-pyrazol-1-yl)-6-methyl-4-pyrimidinamine;N-Cyclohexyl-N-[2-(3,5-diMethyl-pyrazol-1-yl)-6-Methyl-4-pyriMid;4-PyriMidinaMine, N-cyclohexyl-2-(3,5-diMethyl-1H-pyrazol-1-yl)-6-Methyl-;N-Cyclohexyl-N-[2-(3,5-dimethylpyrazol-1-yl)-6-methylpyrimidin-4-yl]amine;N-Cyclohexyl-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4-amine;N-Cyclohexyl-2-(3,5-dimethyl-1H-pyrazol-1-yl);N-cyclohexyl-6-methyl-2-(3,5-dimethyl-1H-pyrazol-1-yl)pyrimidin-4-amine
Price21 Properties Safety Information Description
21 prices
Selected condition：
Brand
  • Activate Scientific
  • AK Scientific
  • ApexBio Technology
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 2mg
  • 5
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 100mg
  • 25
  • 50mg
  • 10mM(in 1mL DMSO)
  • 250mg
  • 1g
  • ManufacturerActivate Scientific
  • Product numberAS13343
  • Product descriptionN-Cyclohexyl-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4-amine 95+%
  • Packaging250mg
  • Price$335
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberX6337
  • Product descriptionN-Cyclohexyl-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4-amine
  • Packaging10mg
  • Price$233
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7231
  • Product descriptionCyPPA
  • Packaging10mM(in 1mL DMSO)
  • Price$67
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7231
  • Product descriptionCyPPA
  • Packaging10mg
  • Price$179
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7231
  • Product descriptionCyPPA
  • Packaging50mg
  • Price$753
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC44203
  • Product descriptionN-Cyclohexyl-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4-amine
  • Packaging1mg
  • Price$96
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC44203
  • Product descriptionN-Cyclohexyl-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4-amine
  • Packaging2mg
  • Price$154
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC44203
  • Product descriptionN-Cyclohexyl-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4-amine
  • Packaging5mg
  • Price$280
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC44203
  • Product descriptionN-Cyclohexyl-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4-amine
  • Packaging10mg
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC44203
  • Product descriptionN-Cyclohexyl-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4-amine
  • Packaging25mg
  • Price$950
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15614
  • Product descriptionCyPPA ≥98%
  • Packaging10mg
  • Price$127
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15614
  • Product descriptionCyPPA ≥98%
  • Packaging50mg
  • Price$601
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM167841
  • Product descriptionN-Cyclohexyl-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4-amine 95+%
  • Packaging100mg
  • Price$392
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM167841
  • Product descriptionN-Cyclohexyl-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4-amine 95+%
  • Packaging250mg
  • Price$610
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM167841
  • Product descriptionN-Cyclohexyl-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4-amine 95+%
  • Packaging1g
  • Price$1219
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberC5493
  • Product descriptionCyPPA ≥98% (HPLC), solid
  • Packaging5mg
  • Price$149
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Activate Scientific AS13343 N-Cyclohexyl-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4-amine 95+% 250mg $335 2021-12-16 Buy
AK Scientific X6337 N-Cyclohexyl-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4-amine 10mg $233 2021-12-16 Buy
ApexBio Technology B7231 CyPPA 10mM(in 1mL DMSO) $67 2021-12-16 Buy
ApexBio Technology B7231 CyPPA 10mg $179 2021-12-16 Buy
ApexBio Technology B7231 CyPPA 50mg $753 2021-12-16 Buy
Biosynth Carbosynth FC44203 N-Cyclohexyl-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4-amine 1mg $96 2021-12-16 Buy
Biosynth Carbosynth FC44203 N-Cyclohexyl-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4-amine 2mg $154 2021-12-16 Buy
Biosynth Carbosynth FC44203 N-Cyclohexyl-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4-amine 5mg $280 2021-12-16 Buy
Biosynth Carbosynth FC44203 N-Cyclohexyl-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4-amine 10mg $450 2021-12-16 Buy
Biosynth Carbosynth FC44203 N-Cyclohexyl-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4-amine 25mg $950 2021-12-16 Buy
Cayman Chemical 15614 CyPPA ≥98% 10mg $127 2024-03-01 Buy
Cayman Chemical 15614 CyPPA ≥98% 50mg $601 2024-03-01 Buy
Chemenu CM167841 N-Cyclohexyl-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4-amine 95+% 100mg $392 2021-12-16 Buy
Chemenu CM167841 N-Cyclohexyl-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4-amine 95+% 250mg $610 2021-12-16 Buy
Chemenu CM167841 N-Cyclohexyl-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4-amine 95+% 1g $1219 2021-12-16 Buy
Sigma-Aldrich C5493 CyPPA ≥98% (HPLC), solid 5mg $149 2024-03-01 Buy
Next Last

Properties

Boiling point :512.2±42.0 °C(Predicted)
Density :1.23
storage temp. :2-8°C
solubility :DMSO: >10mg/mL
pka :4.19±0.10(Predicted)
form :solid
color :white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P273 Avoid release to the environment.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

CyPPA is a positive modulator of the small conductance calcium-activated potassium channels SK2 and SK3 (EC50s = 14 and 5.6 μM, respectively). It is inactive on both SK1 and the intermediate conductance calcium-activated potassium channel, IK. At SK3, CyPPA increases the apparent calcium-sensitivity of channel activation, changing the EC50 value of calcium activation from 429 to 59 nM. CyPPA is used to evaluate the roles of SK2 and SK3 in such diverse processes as memory encoding, uterine muscle contraction, and dopamine signaling.

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