6-[4-(2-Piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine
![6-[4-(2-Piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine price.](/CAS/GIF/866405-64-3.gif)
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- $8 - $2492
- Product name: 6-[4-(2-Piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine
- CAS: 866405-64-3
- MF: C24H25N5O
- MW: 399.49
- EINECS:
- MDL Number:MFCD08705402
- Synonyms:AMPK INHIBITOR;AMPK Inhibitor, Compound C, Dorsomorphin;6-[4-[2-(1-Piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)-pyrazolo[1,5-a]pyrimidinedihydrochloride;Pyrazolo[1,5-a]pyriMidine, 6-[4-[2-(1-piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)-;DorsoMorphin, Free Base, >99%;6-(4-(2-(Piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrrazolo[1,5-a]pyrimidine;6-[4-[2-(1-piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)-pyrazolo[1,5-a]pyrimidine;InSolution? AMPK Inhibitor, Compound C
84 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Ark Pharm
- AvaChem
- Axon Medchem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 10mM*1mLinDMSO
- 2mg
- 10
- 1mg
- 50
- 5mg
- 10mg
- 25MG
- 50mg
- 100.00mg
- 100mg
- 200mg
- 250mg
- 250.00mg
- 500mg
- 1g
- 1.00g
- 5G
- 25 mg
- Manufactureraablocks
- Product numberAA003MWN
- Product description6-[4-[2-(1-Piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)pyrazolo[1,5-a]pyrimidine 99%
- Packaging1mg
- Price$13
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003MWN
- Product description6-[4-[2-(1-Piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)pyrazolo[1,5-a]pyrimidine 99%
- Packaging5mg
- Price$22
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003MWN
- Product description6-[4-[2-(1-Piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)pyrazolo[1,5-a]pyrimidine 99%
- Packaging10mg
- Price$29
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003MWN
- Product description6-[4-[2-(1-Piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)pyrazolo[1,5-a]pyrimidine 99%
- Packaging100mg
- Price$93
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003MWN
- Product description6-[4-[2-(1-Piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)pyrazolo[1,5-a]pyrimidine 99%
- Packaging250mg
- Price$156
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003MWN
- Product description6-[4-[2-(1-Piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)pyrazolo[1,5-a]pyrimidine 99%
- Packaging1g
- Price$400
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product number10314
- Product descriptionDorsomorphin 98%
- Packaging1G
- Price$595
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product number10314
- Product descriptionDorsomorphin 98%
- Packaging5G
- Price$1150
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product number10314
- Product descriptionDorsomorphin 98%
- Packaging25MG
- Price$75
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product number10314
- Product descriptionDorsomorphin 98%
- Packaging100MG
- Price$190
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number3601AC
- Product description6-(4-(2-(Piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine
- Packaging50mg
- Price$460
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA137399
- Product description6-(4-(2-(Piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine 99+%
- Packaging1g
- Price$348
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA137399
- Product description6-(4-(2-(Piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine 99+%
- Packaging1mg
- Price$8
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA137399
- Product description6-(4-(2-(Piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine 99+%
- Packaging100mg
- Price$88
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA137399
- Product description6-(4-(2-(Piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine 99+%
- Packaging250mg
- Price$135
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA137399
- Product description6-(4-(2-(Piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine 99+%
- Packaging10mg
- Price$24
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA003MWN | 6-[4-[2-(1-Piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)pyrazolo[1,5-a]pyrimidine 99% | 1mg | $13 | 2026-05-28 | Buy |
| aablocks | AA003MWN | 6-[4-[2-(1-Piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)pyrazolo[1,5-a]pyrimidine 99% | 5mg | $22 | 2026-05-28 | Buy |
| aablocks | AA003MWN | 6-[4-[2-(1-Piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)pyrazolo[1,5-a]pyrimidine 99% | 10mg | $29 | 2026-05-28 | Buy |
| aablocks | AA003MWN | 6-[4-[2-(1-Piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)pyrazolo[1,5-a]pyrimidine 99% | 100mg | $93 | 2026-05-28 | Buy |
| aablocks | AA003MWN | 6-[4-[2-(1-Piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)pyrazolo[1,5-a]pyrimidine 99% | 250mg | $156 | 2026-05-28 | Buy |
| aablocks | AA003MWN | 6-[4-[2-(1-Piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)pyrazolo[1,5-a]pyrimidine 99% | 1g | $400 | 2026-05-28 | Buy |
| ACHEMBLOCK | 10314 | Dorsomorphin 98% | 1G | $595 | 2026-05-27 | Buy |
| ACHEMBLOCK | 10314 | Dorsomorphin 98% | 5G | $1150 | 2026-05-27 | Buy |
| ACHEMBLOCK | 10314 | Dorsomorphin 98% | 25MG | $75 | 2026-05-27 | Buy |
| ACHEMBLOCK | 10314 | Dorsomorphin 98% | 100MG | $190 | 2026-05-27 | Buy |
| AK Scientific | 3601AC | 6-(4-(2-(Piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine | 50mg | $460 | 2021-12-16 | Buy |
| Ambeed | A137399 | 6-(4-(2-(Piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine 99+% | 1g | $348 | 2021-12-16 | Buy |
| Ambeed | A137399 | 6-(4-(2-(Piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine 99+% | 1mg | $8 | 2021-12-16 | Buy |
| Ambeed | A137399 | 6-(4-(2-(Piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine 99+% | 100mg | $88 | 2021-12-16 | Buy |
| Ambeed | A137399 | 6-(4-(2-(Piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine 99+% | 250mg | $135 | 2021-12-16 | Buy |
| Ambeed | A137399 | 6-(4-(2-(Piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine 99+% | 10mg | $24 | 2021-12-16 | Buy |
Properties
Melting point :>228°C(dec.)
Density :1.25±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >2mg/mL (warmed)
pka :8.53±0.10(Predicted)
form :powder
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChI :InChI=1S/C24H25N5O/c1-2-12-28(13-3-1)14-15-30-22-6-4-19(5-7-22)21-16-26-24-23(17-27-29(24)18-21)20-8-10-25-11-9-20/h4-11,16-18H,1-3,12-15H2
InChIKey :XHBVYDAKJHETMP-UHFFFAOYSA-N
SMILES :C12=C(C3C=CN=CC=3)C=NN1C=C(C1=CC=C(OCCN3CCCCC3)C=C1)C=N2
Density :1.25±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >2mg/mL (warmed)
pka :8.53±0.10(Predicted)
form :powder
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChI :InChI=1S/C24H25N5O/c1-2-12-28(13-3-1)14-15-30-22-6-4-19(5-7-22)21-16-26-24-23(17-27-29(24)18-21)20-8-10-25-11-9-20/h4-11,16-18H,1-3,12-15H2
InChIKey :XHBVYDAKJHETMP-UHFFFAOYSA-N
SMILES :C12=C(C3C=CN=CC=3)C=NN1C=C(C1=CC=C(OCCN3CCCCC3)C=C1)C=N2
Safety Information
| Symbol(GHS): |
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| Signal word: | Warning | ||||||||||||||
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Description
Dorsomorphin is a potent, reversible inhibitor of AMPK (Ki = 109 nM) that does not exhibit significant activity on structurally related kinases, including ZAPK, SYK, PKCθ, PKA, and JAK3. Dorsomorphin can also dose-dependently inhibit the bone morphogenetic protein type 1 receptors ACTR-I (ALK2), BMPR-IA (ALK3), and BMPR-IB (ALK6). Independent of AMPK inhibition, dorsomorphin at 10 μM has additionally been shown to downregulate the Akt/mTOR pathway to induce autophagy in U251 human glioma cells.Related product price
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