Ripasudil hydrochloride dihydrate
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- $93 - $1920
- Product name: Ripasudil hydrochloride dihydrate
- CAS: 887375-67-9
- MF: C15H21ClFN3O3S
- MW: 377.86
- EINECS:
- MDL Number:MFCD26960897
- Synonyms:K-115 HCL;Ripasudil free base;RipasudilHCl Hydrate;K115 HCl Dihydrate;RIPASUDIL HYDROCHLORIDE HYDRATE;(2S)-1-[(4-Fluoro-5-isoquinolinyl)sulfonyl]hexahydro-2-methyl-1H-1,4-diazepine monohydrochloride dihydrate;K-115 (HCl H2O);Ripasudil HCl Dihydrate
25 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- ApexBio Technology
- Biosynth Carbosynth
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- TRC
Package
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number3757AH
- Product descriptionK-115
- Packaging5mg
- Price$200
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA130094
- Product descriptionK-115HydrochlorideDihydrate 98+%
- Packaging2mg
- Price$93
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA130094
- Product descriptionK-115HydrochlorideDihydrate 98+%
- Packaging5mg
- Price$139
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA130094
- Product descriptionK-115HydrochlorideDihydrate 98+%
- Packaging10mg
- Price$186
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA130094
- Product descriptionK-115HydrochlorideDihydrate 98+%
- Packaging25mg
- Price$242
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA130094
- Product descriptionK-115HydrochlorideDihydrate 98+%
- Packaging50mg
- Price$315
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA130094
- Product descriptionK-115HydrochlorideDihydrate 98+%
- Packaging100mg
- Price$410
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA130094
- Product descriptionK-115HydrochlorideDihydrate 98+%
- Packaging250mg
- Price$590
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA130094
- Product descriptionK-115HydrochlorideDihydrate 98+%
- Packaging1g
- Price$1480
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4809
- Product descriptionK-115
- Packaging5mg
- Price$135
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4809
- Product descriptionK-115
- Packaging25mg
- Price$485
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFR162274
- Product descriptionRipasudil HCl hydrate
- Packaging50mg
- Price$700
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFR162274
- Product descriptionRipasudil HCl hydrate
- Packaging25mg
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFR162274
- Product descriptionRipasudil HCl hydrate
- Packaging10mg
- Price$300
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFR162274
- Product descriptionRipasudil HCl hydrate
- Packaging5mg
- Price$200
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFR162274
- Product descriptionRipasudil HCl hydrate
- Packaging2mg
- Price$125
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 3757AH | K-115 | 5mg | $200 | 2021-12-16 | Buy |
| Ambeed | A130094 | K-115HydrochlorideDihydrate 98+% | 2mg | $93 | 2021-12-16 | Buy |
| Ambeed | A130094 | K-115HydrochlorideDihydrate 98+% | 5mg | $139 | 2021-12-16 | Buy |
| Ambeed | A130094 | K-115HydrochlorideDihydrate 98+% | 10mg | $186 | 2021-12-16 | Buy |
| Ambeed | A130094 | K-115HydrochlorideDihydrate 98+% | 25mg | $242 | 2021-12-16 | Buy |
| Ambeed | A130094 | K-115HydrochlorideDihydrate 98+% | 50mg | $315 | 2021-12-16 | Buy |
| Ambeed | A130094 | K-115HydrochlorideDihydrate 98+% | 100mg | $410 | 2021-12-16 | Buy |
| Ambeed | A130094 | K-115HydrochlorideDihydrate 98+% | 250mg | $590 | 2021-12-16 | Buy |
| Ambeed | A130094 | K-115HydrochlorideDihydrate 98+% | 1g | $1480 | 2021-12-16 | Buy |
| ApexBio Technology | B4809 | K-115 | 5mg | $135 | 2021-12-16 | Buy |
| ApexBio Technology | B4809 | K-115 | 25mg | $485 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FR162274 | Ripasudil HCl hydrate | 50mg | $700 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FR162274 | Ripasudil HCl hydrate | 25mg | $450 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FR162274 | Ripasudil HCl hydrate | 10mg | $300 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FR162274 | Ripasudil HCl hydrate | 5mg | $200 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FR162274 | Ripasudil HCl hydrate | 2mg | $125 | 2021-12-16 | Buy |
Properties
storage temp. :Store at -20°C
solubility :insoluble in EtOH; ≥123.2 mg/mL in DMSO; ≥41.7 mg/mL in H2O
form :solid
Stability :Hygroscopic
solubility :insoluble in EtOH; ≥123.2 mg/mL in DMSO; ≥41.7 mg/mL in H2O
form :solid
Stability :Hygroscopic
Safety Information
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Description
Ripasudil hydrochloride hydrate (Glanatec®) was approved in Japan in 2014 for the treatment of glaucoma and ocular hypertension. Originally discovered by D. Western Therapeutics Institute, Inc. and licensed by the Kowa Company, Ltd, ripasudil functions as a selective Rho-kinase inhibitor and reduces intraocular pressure by stimulation of aqueous humour drainage of the trabecular meshwork. While this recent approval allows for use of ripasudil as a twice-daily monotherapy treatment when other drugs cannot be used or are not effective, clinical trials using ripasudil as a combination therapy with other glaucoma drugs have shown promising results in the treatment of primary open-angle glaucoma or ocular hypertension. Currently, the Kowa Company is also pursuing trials focused on the use of ripasudil for the treatment of diabetic retinopathy and diabetic macular edema.More related product prices
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